Functional Annotation
Mostrando 1-12 de 229 artigos, teses e dissertações.
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1. Urethral reconstruction and genitoplasty highlighted in International Brazilian Journal of Urology
ABSTRACT Objective: Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a chronic inflammatory disease that can cause bladder pain and accompanying symptoms, such as long-term urinary frequency and urgency. IC/BPS can be ulcerative or non-ulcerative. The aim of this study was to explore the core genes involved in the pathogenesis of ulcerative IC, and
Int. braz j urol.. Publicado em: 2021-08
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2. Exploration of the core genes in ulcerative interstitial cystitis/bladder pain syndrome
ABSTRACT Objective: Interstitial cystitis (IC)/bladder pain syndrome (BPS) is a chronic inflammatory disease that can cause bladder pain and accompanying symptoms, such as long-term urinary frequency and urgency. IC/BPS can be ulcerative or non-ulcerative. The aim of this study was to explore the core genes involved in the pathogenesis of ulcerative IC, and
Int. braz j urol.. Publicado em: 2021-08
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3. Determining the pathogenicity of CFTR missense variants: Multiple comparisons of in silico predictors and variant annotation databases
Abstract Pathogenic variants in the Cystic Fibrosis Transmembrane Conductance Regulator gene (CFTR) are responsible for cystic fibrosis (CF), the commonest monogenic autosomal recessive disease, and CFTR-related disorders in infants and youth. Diagnosis of such diseases relies on clinical, functional, and molecular studies. To date, over 2,000 variants have
Genet. Mol. Biol.. Publicado em: 14/11/2019
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4. Identification of the molecular mechanisms associated with acute type A aortic dissection through bioinformatics methods
Aortic dissection is characterized by the redirection of blood flow, which flows through an intimal tear into the aortic media. The purpose of this study was to find potential acute type A aortic dissection (AAAD)-related genes and molecular mechanisms by bioinformatics. The gene expression profiles of GSE52093 were obtained from Gene Expression Omnibus (GEO
Braz J Med Biol Res. Publicado em: 07/11/2019
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5. [PROVISIONAL] Genome sequence of Shewanella corallii strain A687 isolated from pufferfish (Sphoeroides spengleri)
Abstract We present here the genome sequence of Shewanella corallii strain A687 isolated from pufferfish Sphoeroides spengleri (Family Tetraodontidae). The assembly consists of 5,215,037 bp and contains 284 contigs, with a G+C content of 50.3%. The genus Shewanella comprises 67 recognized species. These bacteria are Gram-negative, rod-shaped, facultatively a
Genet. Mol. Biol.. Publicado em: 02/09/2019
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6. Modelagem de processos de negócio: efeito do método de notação no nível de ambiguidade
Resumo A proposta deste estudo experimental controlado e aleatorizado foi analisar a especificação de requisitos funcionais. Avaliaram-se os possíveis impactos do método de notação de modelagem de processo no nível de ambiguidade presente na especificação em linguagem natural. As notações foram utilizadas como instrumento para manifestar as nece
Gest. Prod.. Publicado em: 18/03/2019
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7. Deep sequencing analysis of toad Rhinella schneideri skin glands and partial biochemical characterization of its cutaneous secretion
Abstract Background: Animal poisons and venoms are sources of biomolecules naturally selected. Rhinella schneideri toads are widespread in the whole Brazilian territory and they have poison glands and mucous gland. Recently, protein from toads’ secretion has gaining attention. Frog skin is widely known to present great number of host defense peptides and
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 17/12/2018
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8. Verbal and Verbal-Visual Logico-Semantic Relations in Picturebooks: an English-Brazilian Portuguese Parallel Corpus Study
Abstract: This article presents a methodology to analyze verbal and verbal-visual logico-semantic relations in picturebooks originally written in English and their translations into Brazilian Portuguese. Drawing on systemic-functional theory (Halliday & Matthiessen, 2014) and on Visual Grammar (Kress & van Leeuwen, 2006), verbal and visual texts in picturebo
Ilha Desterro. Publicado em: 2018-01
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9. The search for novel insecticide targets in the post-genomics era, with a specific focus on G-protein coupled receptors
Insects are considered pests globally, implicated in the destruction of agricultural fields and transmission of pathogens that cause deadly human diseases, such as dengue, Zika and malaria. The diversity of the insecticide arsenal has remained stagnant for decades, but the recent rise of insecticide resistance fueled the discovery of novel modes of action, a
Mem. Inst. Oswaldo Cruz. Publicado em: 2017-01
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10. Gene expression profile analysis of human intervertebral disc degeneration
In this study, we used microarray analysis to investigate the biogenesis and progression of intervertebral disc degeneration. The gene expression profiles of 37 disc tissue samples obtained from patients with herniated discs and degenerative disc disease collected by the National Cancer Institute Cooperative Tissue Network were analyzed. Differentially expre
Genet. Mol. Biol.. Publicado em: 2013
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11. Development of EGene platform for functional annotation and database integration: application and validation on transcript sequences of Eimeria spp. of domestic fowl. / Desenvolvimento da plataforma EGene para anotação funcional e integração com banco de dados: aplicação e validação em transcritos de Eimeria spp. de galinha doméstica.
Parasitas protozoários do gênero Eimeria causam doenças entéricas na galinha doméstica. Nosso grupo gerou 15.000 sequências ORESTES para cada uma das três mais importantes espécies: E. tenella, E. maxima e E. acervulina. Nesse trabalho relatamos o desenvolvimento de alguns componentes da plataforma EGene (Durham et al. Bioinformatics 21: 2812-2813, 2
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/01/2012
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12. Xylella fastidiosa comparative genomic database is an information resource to explore the annotation, genomic features, and biology of different strains
The Xylella fastidiosa comparative genomic database is a scientific resource with the aim to provide a user-friendly interface for accessing high-quality manually curated genomic annotation and comparative sequence analysis, as well as for identifying and mapping prophage-like elements, a marked feature of Xylella genomes. Here we describe a database and too
Genetics and Molecular Biology. Publicado em: 16/02/2012