Gastroprotective Action
Mostrando 1-12 de 19 artigos, teses e dissertações.
-
1. Antinociceptive and anti-inflammatory activities of a triterpene-rich fraction from Himatanthus drasticus
Himatanthus drasticus (Mart.) Plumel belongs to the Apocynaceae family and the latex from its trunk bark (Hd) is known as “janaguba milk”. This latex is widely used in Northeast Brazil, mainly in the Cariri region, for its gastroprotective, anti-inflammatory, and antitumor properties. The objective of this study was to investigate a triterpene-rich fract
Braz J Med Biol Res. Publicado em: 16/05/2019
-
2. Himatanthus drasticus: a chemical and pharmacological review of this medicinal species, commonly found in the Brazilian Northeastern region
ABSTRACT In order to compile the empirical use, as well as the chemical, pharmacological and biological aspects of Himatanthus drasticus (Mart.) Plumel, Apocynaceae, a review was carried out by searching PubMed, Google Scholar, Scientific Electronic Online Library, Web of Science, Science Direct, Scopus and Cochrane. For that, works in English, Spanish and P
Rev. bras. farmacogn.. Publicado em: 2017-12
-
3. InvestigaÃÃo dos mecanismos de aÃÃo da atividade gastroprotetora de 1,4-cineol em modelos de Ãlcera gÃstrica em camundongos. / Investigation of mechanisms of action of gastroprotective activity of 1,4-cineole in gastric ulcer models in mice.
1,4-Cineol à um monoterpeno Ãter amplamente distribuido, o qual à um dos constituintes responsÃveis pelo odor do limÃo. O objetivo deste trabalho foi avaliar o efeito gastroprotetor de 1,4-Cineol (CIN 100 e 200 mg/Kg) nos modelos de lesÃo induzidas por etanol ou piroxicam em camundongos e, posteriormente, investigar os possÃveis mecanismos de aÃÃo f
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/08/2012
-
4. Gastroprotective effect of leaf extracts of Basella alba var. alba against experimental gastric ulcers in rats
The aqueous and ethanol extracts of the leaves of Basella alba L. var. alba Wight, Basellaceae, were investigated for antiulcer activity on rats employing the pylorus ligation and ethanol induced ulcer models. The various gastric secretion parameters such as total acidity, free acidity, gastric acid volume, pH and histopathological parameters such as ulcer i
Revista Brasileira de Farmacognosia. Publicado em: 08/03/2012
-
5. Gastroprotective effect of Byrsonima sericea DC leaf extract against ethanol-induced gastric injury and its possible mechanisms of action
Folhas de Byrsonima sericea são amplamente utilizadas na medicina popular no Brasil no tratamento de distúrbios gástricos. Este estudo investigou os constituintes químicos do extrato etanólico das folhas de B. sericea (BSLE) e sua atividade gastroprotetora com seus possíveis mecanismos de ação utilizando o modelo de lesão gástrica induzida por etan
Anais da Academia Brasileira de Ciências. Publicado em: 29/02/2012
-
6. AvaliaÃÃo do efeito do (-)-α-bisabolol em parÃmetros de estresse oxidativo em camundongos submetido ao tratamento agudo com etanol absoluto. / EVALUATION OF THE EFFECT OF (-)-α-BISABOLOL IN PARAMETERS OF OXIDATIVE STRESS IN MICE SUBMITTED TO ABSOLUTE ETHANOL ACUTE TREATMENT.
The (-)-α-bisabolol, at doses of 100 and 200 mg / kg, is an alcohol commonly obtained from Matricaria chamomilla and species of the genus (Vanillosmopsis), it was tested in ethanol-induced gastric injury model for research gastroprotective effect microscopically of this drug, the influence of neutrophil migration in this effect, as well as THE involveme
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/01/2011
-
7. Antiulcerogenic activity of the extracts of Struthanthus marginatus
The gastroprotective action of the aqueous extract (AE) and the hydroalcoholic extract obtained from the leaves of Struthanthus marginatus (Desr.) Blume, Loranthaceae, were performed with in vivo models in rodents using: ethanol, indomethacin or stress-induced ulcers, determination of gastric secretion and the mucus production. The scavenger activity of AE i
Revista Brasileira de Farmacognosia. Publicado em: 26/08/2011
-
8. Gastroprotective effects of essential oil from Protium heptaphyllum on experimental gastric ulcer models in rats
Peptic ulcers are a common disorder of the entire gastrointestinal tract, its etiology has not been completely elucidated. The basic physiopathological of peptic ulcers result from an imbalance between some endogenous aggressive factor and cytoprotective factors. The treatment of this disease is usually done with antacids or proton pump, but are currently be
Revista Brasileira de Farmacognosia. Publicado em: 08/07/2011
-
9. PRELIMINARY PHYTOCHEMICAL PROFILE AND EVALUATION OF GASTROPROCTIVE ACTIVE OF HIDROALCOHOLIC EXTRACT, FRACTIONS AND SUBFRACTIONS OF KALE LEAVES (Brassica oleracea L. var. acephala DC.) / Estudo do perfil fitoquímico e avaliação da atividade gastroprotetora do extrato hidroalcoólico, frações e subfrações das folhas de couve: Brassica oleracea L. var. acephala DC.
P opular reports indicate that kale, Brassica oleracea L. var. acephala DC., when taken while fasting, in the form of a juice, relieves the symptoms of gastric disorders. Studies show that some compounds present in plants of this genus exhibit antioxidant, wound healing, antimicrobial, anti-inflammatory and anticancer activity. Thus, this study investigates
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/07/2010
-
10. AvaliaÃÃo dos efeitos farmacolÃgicos de (-)- mentol em modelos comportamentais e de gastroproteÃÃo em camundongos / Assessment of the effects of (-)-menthol on behavioral and gastroprotective models in mice.
O mentol, constituinte majoritÃrio da hortelÃ-pimenta, foi avaliado em modelos animais para investigar sua atividade no sistema nervoso central atravÃs de modelos experimentais animais para depressÃo, ansiedade, sedaÃÃo e convulsÃo, tais como, nado forÃado (NF), suspensÃo da cauda (SC), campo aberto, labirinto em cruz elevado (LCE), rota rod, tempo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/11/2009
-
11. InvestigaÃÃo dos efeitos centrais e gastroprotetores do isopulegol em camundongos / Evaluation of the central nervous system and gastroprotective effects of isopulegol in mice.
Isopulegol is a monoterpene alcohol present in the essential oils of various plants, and has been used in the manufacture of fragrances with blossom compositions. In order to investigate its effects on animal models of CNS actions, isopulegol was administered to male Swiss mice at single doses of 25 and 50 mg/kg 30 (i.p.) or 60 min (p.o.) before the experime
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/08/2009
-
12. GASTROPROTECTIVE AND ANTIMICROBIAL ACTIVITIES OF MATRICARIA RECUTITA (CAMOMILA) FLOWER EXTRACT AND ALPHA-BISABOLOL: POSSIBLE MECHANISMS OF ACTION / Potencial farmacolÃgico do extrato seco de matricaria recutita (Chamomilla) e do Alfa-Bisabolol
Matricaria recutita, commonly known as chamomile, is a plant species used in medicine due to its sedative properties, anti-inflammatory and healing, among others. Alpha-bisabolol, a sesquiterpene present in essential oil, also has several pharmacological activities recognized. This work evaluated the gastroprotective activity, antioxidant, antimicrobial and
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/08/2009