Gene Expression Programming
Mostrando 1-12 de 27 artigos, teses e dissertações.
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1. Prediction the effects of ZnO2 nanoparticles on splitting tensile strength and water absorption of high strength concrete
In the present paper, two models based on artificial neural networks (ANN) and gene expression programming (GEP) for predicting splitting tensile strength and water absorption of concretes containing ZnO2 nanoparticles at different ages of curing have been developed. To build these models, training and testing using experimental results for 144 specimens pro
Materials Research. Publicado em: 07/06/2012
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2. Efeito da restrição protéica materna durante a lactação sobre a resposta de timócitos da prole jovem de ratos Wistar / Maternal protein deprivation during lactation increases leptin activity and inhibits apoptosis of thymic cells from young offspring
In this study, we investigated the consequences of maternal protein deprivation during lactation on thymocyte responses of the offspring Wistar rats (PD group) and the role of leptin in these alterations. Compared to group C, PD animals showed at 30 days of age, lower body and thymus weights, with no alteration in the thymocyte number or any difference in th
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/03/2011
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3. D-MaPs - DNA-microarray projects: web-based software for multi-platform microarray analysis
The web application D-Maps provides a user-friendly interface to researchers performing studies based on microarrays. The program was developed to manage and process one- or two-color microarray data obtained from several platforms (currently, GeneTAC, ScanArray, CodeLink, NimbleGen and Affymetrix). Despite the availability of many algorithms and many softwa
Genetics and Molecular Biology. Publicado em: 2009
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4. Pipeline for macro- and microarray analyses
The pipeline for macro- and microarray analyses (PMmA) is a set of scripts with a web interface developed to analyze DNA array data generated by array image quantification software. PMmA is designed for use with single- or double-color array data and to work as a pipeline in five classes (data format, normalization, data analysis, clustering, and array maps)
Brazilian Journal of Medical and Biological Research. Publicado em: 13/04/2007
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5. RegressÃo simbÃlica via programaÃÃo genÃtica: um estudo de caso com modelagem geofÃsica
Symbolic regression, which is in principal the handling of mathematical expressions for finding a function that describes a data set, was until recently carried out exclusively by humans. But now, several computational techniques of symbolic regression automatization have appeared. One of these techniques is genetic programming, a subarea of evolutive comput
Publicado em: 2006
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6. Regressão simbólica via programação genética: um estudo de caso com modelagem geofísica
A regressão simbólica, que consiste na manipulação de expressões matemáticas para descoberta de funções que descrevam um conjunto de dados, foi uma tarefa exclusivamente humana até pouco tempo atrás. Recentemente, foram desenvolvidas várias técnicas computacionais para automatizar a regressão simbólica. Uma dessas técnicas é a programação g
Publicado em: 2006
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7. MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2.
During their lifespan, immature cells normally pass through sequential transitions to a differentiated state and eventually undergo cell death. This progression is aberrant in cancer, although the transition to differentiation can be reestablished in inducible leukemia cell lines. This report describes a gene, MCL1, that we isolated from the ML-1 human myelo
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8. Hypermethylation of Homeobox A10 by in Utero Diethylstilbestrol Exposure: An Epigenetic Mechanism for Altered Developmental Programming
Diethylstilbestrol (DES) is a nonsteroidal estrogen that induces developmental anomalies of the female reproductive tract. The homeobox gene HOXA10 controls uterine organogenesis, and its expression is altered after in utero DES exposure. We hypothesized that an epigenetic mechanism underlies DES-mediated alterations in HOXA10 expression. We analyzed the exp
The Endocrine Society.
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9. Telomere interactions may condition the programming of antigen expression in Trypanosoma brucei.
The AnTat 1.1 antigen type typically occurs late in a chronic infection by the EATRO 1125 stock of Trypanosoma brucei. The AnTat 1.1 gene, which is located 24 kb from a chromosome end, seems exclusively expressed by acting as a donor in gene conversion events targeted to the telomeric expression site. We report that this gene is sufficiently provided with th
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10. Differential gene-expression patterns in genital fibroblasts of normal males and 46,XY females with androgen insensitivity syndrome: evidence for early programming involving the androgen receptor
Most individuals with androgen insensitivity syndrome (AIS) carry germline mutations of the androgen receptor (AR) that interfere with or ablate its function. As genital fibroblasts retain expression of the AR in vitro, genital skin fibroblasts from normal males and 46,XY females with complete AIS due to known AR mutations were analysed using microarrays to
BioMed Central.
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11. Use of recombinant DNA technology to program eukaryotic cells to synthesize rat proinsulin: a rapid expression assay for cloned genes.
To use recombinant DNA technology to functionally analyze mutations introduced into cloned eukaryotic genes, a rapid procedure is necessary to assay the steps along the gene expression pathway. Since cloned rat insulin genes are not transcribed efficiently after transfection into various cell lines, I have asked whether one could drive expression by placing
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12. General and Specific Alterations in Programming of Global Viral Gene Expression during Infection by VP16 Activation-Deficient Mutants of Herpes Simplex Virus Type 1
During productive infection by herpes simplex virus 1 (HSV-1), viral gene expression occurs in a temporally regulated cascade in which transcription of the viral immediate-early (IE) genes is strongly stimulated by the virion protein VP16. We have employed an oligonucleotide microarray to examine the effect of VP16 mutations on the overall pattern of viral g
American Society for Microbiology.