Gene Igfbp7 Humano
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1. Bone marrow stroma modulates the expression of several drug resistance/sensitivity genes in pediatric acute limphoblastic leukemia / O estroma da medula ossea e a sua influencia na expressão de genes de resistencia e sensibilidade a quimioterapicos na leucemia linfoide aguda (LLA) pediatrica
The intrinsic or acquired chemotherapy resistance composites one of the most important causes of failures in the treatment of pediatric ALL. The ALL and bone marrow microenvironment nteraction contributes for the proliferation and resistance to the chemotherapy regimen of leukemic cells probably through a great variety of cellular mechanisms, including incre
Publicado em: 2007