Genetic Effects
Mostrando 1-12 de 2590 artigos, teses e dissertações.
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1. The effect of alpha-2A adrenergic receptor (ADRA2A) genetic polymorphisms on the depth of sedation of dexmedetomidine: a genetic observational pilot study
Abstract Background: The genetic polymorphisms of the alpha-2A adrenergic receptor (ADRA2A), which plays a significant role in sedation, anxiety relief, and antinociception, particularly in dexmedetomidine, may differ in the degree of sedation. This study aimed to investigate the effect of the genetic polymorphisms of ADRA2A (rs11195418, rs1800544, rs248451
Brazilian Journal of Anesthesiology. Publicado em: 2022
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2. Heritability of resistance to potato late blight in an F1 population of elite potato cultivars
ABSTRACT Phytophthora infestans is the most important disease in potato crops. Its control is based on the use of chemical products that have developed pathogen resistance and high economic and environmental impacts. To reduce these effects, the use of plant varieties or cultivars resistant to this pathogen has been proposed. The aim of this study was to eva
Revista Ceres. Publicado em: 2022
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3. The impact of the genetic background in a patient with papillary thyroid cancer and familial adenomatous polyposis
SUMMARY Thyroid cancer is the most common endocrine malignancy, and papillary thyroid carcinoma (PTC) is the main subtype. The cribriform morular variant is a histological phenotype of PTC characterized by its relationship with familial adenomatous polyposis (FAP). Description of the case: We report the genetic assessment of a 20-year-old female patient diag
Archives of Endocrinology and Metabolism. Publicado em: 2022
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4. Expansion of cord blood stem cells in fibronectin-coated microfluidic bioreactor
ABSTRACT Background: Hematopoietic stem/progenitor cell transplantation is the main treatment option for hematological malignancies and disorders. One strategy to solve the problem of low stem cell doses used in transplantation is pre-transplant expansion. We hypothesized that using fibronectin-coated microfluidic channels would expand HSPCs and keep self-r
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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5. EFFECTS OF GENETIC VARIATIONS OF MLCK2, AMPD1, AND COL5A1 ON MUSCLE ENDURANCE
RESUMO Introdução: Embora tenham sido detectadas possíveis relações entre variantes genéticas de MLCK2, AMPD1 e COL5A1 em estudos moleculares que avaliam o desempenho esportivo do ponto de vista genético, os dados são limitados no que diz respeito à resistência muscular e à aptidão física. Materiais e Métodos: Este estudo objetivou avaliar es
Revista Brasileira de Medicina do Esporte. Publicado em: 2022
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6. Interstitial lung disease due to anti-TNF use in the treatment of psoriasis
Abstract Psoriasis is a chronic inflammatory disease that affects the skin variably, according to genetic and environmental factors. Some patients may benefit from systemic treatment with immunobiological agents, drugs that can be accompanied by several adverse effects. A case of a 58-year-old patient undergoing treatment for psoriasis with adalimumab for fi
An. Bras. Dermatol.. Publicado em: 2021-08
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7. GROWTH PROMOTION OF GENETICALLY IMPROVED Pinus taeda SEEDLINGS BY INOCULATION WITH SPECIES OF Bacillus.
ABSTRACT This study was carried on evaluating effects of inoculation with Bacillus species and generations of genetically improved seeds on Pinus taeda growth in nursery conditions. Two experiments, based on distinct inoculation methods (sowing and post-emergence) were performed under a 3 x 2 factorial, completely randomized block design (3 levels of inocula
CERNE. Publicado em: 2020-12
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8. Quantifying individual variation in reaction norms using random regression models fitted through Legendre polynomials: application in eucalyptus breeding
ABSTRACT An accurate, efficient and informative statistical method for analyses of genotype × environment (G × E) interactions is a key requirement for progress in any breeding program. Thus, the objective of this study was to quantify individual variation in reaction norms using random regression models fitted through Legendre polynomials in eucalyptus (E
Bragantia. Publicado em: 2020-12
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9. EFEITOS DA CANOAGEM NAS HABILIDADES MOTORAS DE CRIANÇAS E ADOLESCENTES COM SÍNDROME DE DOWN
RESUMO Introduction Down syndrome (DS) is a genetic condition characterized by an inadequate numerical distribution in chromosome pairing, with extra genetic material related to pair 21 leading to alterations that affect the development of several motor components. Objective To analyze the effects of kayak training for eight weeks on the gross motor skills
Rev Bras Med Esporte. Publicado em: 2020-08
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10. Prader-Willi syndrome: endocrine manifestations and management
ABSTRACT Prader-Willi syndrome (PWS) is a genetic disorder caused by the absence of gene expression in the 15q11.2-q13 paternal chromosome. Patients with PWS develop hypothalamic dysfunction that can lead to various endocrine changes such as: obesity, growth hormone deficiency, hypogonadism, hypothyroidism, adrenal insufficiency and low bone mineral density.
Arch. Endocrinol. Metab.. Publicado em: 2020-06
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11. Type 2 diabetes as a major risk factor for COVID-19 severity: a meta-analysis
ABSTRACT Prader-Willi syndrome (PWS) is a genetic disorder caused by the absence of gene expression in the 15q11.2-q13 paternal chromosome. Patients with PWS develop hypothalamic dysfunction that can lead to various endocrine changes such as: obesity, growth hormone deficiency, hypogonadism, hypothyroidism, adrenal insufficiency and low bone mineral density.
Arch. Endocrinol. Metab.. Publicado em: 2020-06
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12. Poisoning by Brachiaria spp. in various lamb breeds at increasing levels of supplementation during growth
RESUMO: O objetivo deste estudo foi avaliar a frequência da intoxicação por Brachiaria spp. nas fases de recria, crescimento e terminação em várias raças de cordeiros em níveis crescentes de suplementação. Quarenta e cinco cordeiros foram utilizados na fase de crescimento em pastagens de Brachiaria spp. com história de intoxicação, distribuídos
Pesq. Vet. Bras.. Publicado em: 10/01/2020