Genetic Study
Mostrando 1-12 de 6656 artigos, teses e dissertações.
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1. Systematic review on fecal calprotectin in cystic fibrosis
Abstract Objectives: Fecal calprotectin is an inflammatory marker used for monitoring intestinal diseases. It has been studied as a marker of intestinal inflammation in cystic fibrosis (CF), a multi-systemic genetic disease caused by alterations to the CFTR gene. Manifestations of the disease favor a systemic inflammation not limited to the respiratory trac
Jornal de Pediatria. Publicado em: 2023
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2. The effect of alpha-2A adrenergic receptor (ADRA2A) genetic polymorphisms on the depth of sedation of dexmedetomidine: a genetic observational pilot study
Abstract Background: The genetic polymorphisms of the alpha-2A adrenergic receptor (ADRA2A), which plays a significant role in sedation, anxiety relief, and antinociception, particularly in dexmedetomidine, may differ in the degree of sedation. This study aimed to investigate the effect of the genetic polymorphisms of ADRA2A (rs11195418, rs1800544, rs248451
Brazilian Journal of Anesthesiology. Publicado em: 2022
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3. Whole-Exome Sequencing (WES) results of 50 patients with chronic kidney diseases: a perspective of Alport syndrome
SUMMARY OBJECTIVE: Chronic kidney disease (CKD) remains one of the major common health problems, and the number of people affected by the disease is progressively increasing in Turkey and worldwide. This study aimed to investigate molecular defects in Alport syndrome (AS) and other genes in patients with clinically suspected CKD using whole-exome sequencing
Revista da Associação Médica Brasileira. Publicado em: 2022
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4. Morpho-agronomic characterization and genetic divergence among pepper accessions
ABSTRACT The germplasm characterization and the analysis of genetic divergence are fundamental requirements to determine the genetic diversity available and peppers have considerable variability not most explored and quantified. Thus, the aim of this study was to characterize morphological and agronomically pepper accessions and their genetic divergence. The
Revista Ceres. Publicado em: 2022
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5. Genetic diversity and correlation network approach on cotton genotypes in southern of Minas Gerais
ABSTRACT The cultivation of Cotton (Gossypium hirsutum) is trending in an upward expansion at Minas Gerais state, Brazil. Due this growth, the breeding program has been demanded for the knowledge about the genetic diversity and correlation between morpho-agronomic traits, to start interesting crosses. The objective of this work was to study the genetic diver
Revista Ceres. Publicado em: 2022
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6. Inbreeding depression and genetic variability of populations for green maize production
ABSTRACT The production of green maize is considerable important for various regions of Brazil. It is vital that breeding programs of public institutions seek to meet the needs of this market sector, which has a relevant social role, mainly on small properties. The aim of this study was to estimate the inbreeding depression and the genetic components (m + a
Revista Ceres. Publicado em: 2022
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7. Investigation of maternal polymorphisms in genes related to glucose homeostasis and the influence on birth weight: a cohort study
Abstract Objectives: To contribute to a better understanding of the maternal genetic mechanisms that influence obstetric outcomes and that are involved in maternal and child health, this study aimed to evaluate the association between maternal genetic variants and the offspring birth weight by analyzing single-nucleotide polymorphisms (SNPs) in genes relate
Jornal de Pediatria. Publicado em: 2022
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8. Cannabinoid receptor gene polymorphisms and cognitive performance in patients with schizophrenia and controls
Objective: To test the hypothesis that genetic variations of cannabinoid receptors contribute to the pathophysiology of cognitive deficits in schizophrenia. Methods: In this genetic association case-control study, cannabinoid receptor polymorphisms CNR1 rs12720071 and CNR2 rs2229579 were tested for association with neurocognitive performance in 69 patients
Brazilian Journal of Psychiatry. Publicado em: 2022
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9. Metabolomic and Histological Response of Passiflora cincinnata Infected with Cowpea aphid-borne mosaic virus (CABMV) Reveals Changes in Asymptomatic and Symptomatic Phases
Passion fruit woodiness disease, caused by the Cowpea aphid-borne mosaic virus (CABMV), is one of the leading phytosanitary challenges of passion fruit production. Passiflora cincinnata has been recognized for its potential in genetic improvement due to its highest resistance to CABMV and other phytopathogens. Metabolomic and histological alterations of P. c
Journal of the Brazilian Chemical Society. Publicado em: 2022
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10. Pediatric population with cystic fibrosis in the centre of Portugal: candidates for new therapies
Abstract Objectives: Cystic fibrosis (CF) is a severe autosomal recessive disease that results from mutations in a gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, a chloride channel. This study aims to characterize the clinical and genetic features of a cohort of pediatric people with CF (PwCF) in the center of Portugal
Jornal de Pediatria. Publicado em: 2022
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11. Genetic variability in Capsicum spp. accessions through multicategorical traits
ABSTRACT Capsicum peppers originate from the American continent. Their culinary and medicinal potential, first exploited by indigenous peoples over 7000 years ago is vast, however more studies are needed. Despite the existence of germplasm banks that house hundreds of accessions of the genus, only a little of this diversity is seen in large markets. In this
Revista Ceres. Publicado em: 2022
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12. Genetic divergence and combined selection for traits that provide high agronomic performance in common bean lines
ABSTRACT The selection of common bean lines with intermediate cycle, upright plant architecture and high grain yield is an important goal of breeding programs. This study proposes to examine the genetic diversity of common bean genotypes for agronomic traits, select superior genotypes for traits that provide high agronomic performance and define promising cr
Revista Ceres. Publicado em: 2022