Genetics Of Resistance
Mostrando 1-12 de 212 artigos, teses e dissertações.
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1. Liaisons dangereuses: cross-border gene flow and dispersal of insecticide resistance-associated genes in the mosquito Aedes aegypti from Brazil and French Guiana
BACKGROUND In recent years, South America has suffered the burden of continuous high impact outbreaks of dengue, chikungunya and Zika. Aedes aegypti is the main mosquito vector of these arboviruses and its control is the only solution to reduce transmission. OBJECTIVES In order to improve vector control it is essential to study mosquito population geneti
Mem. Inst. Oswaldo Cruz. Publicado em: 23/09/2019
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2. Mathematical modelling of vector-borne diseases and insecticide resistance evolution
Abstract Background: Vector-borne diseases are important public health issues and, consequently, in silico models that simulate them can be useful. The susceptible-infected-recovered (SIR) model simulates the population dynamics of an epidemic and can be easily adapted to vector-borne diseases, whereas the Hardy-Weinberg model simulates allele frequencies a
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 08/02/2018
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3. Transcriptome Analysis of Chicken Embryo Fibroblast Cell Infected with Marek’s Disease Virus of GX0101 ∆ LTR
ABSTRACT Marek’s disease (MD), a lymphoproliferative disorder of chickens caused by the MD virus (MDV), is economically significant. The resistance/susceptibility to MD is controlled by host genetics. The host response to different virus strains varies. The pathogenicity of REV-LTR deleted GX0101∆LTR MDV has been previously reported. However, the precise
Rev. Bras. Cienc. Avic.. Publicado em: 2017-06
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4. Genetics of chloroquine-resistant malaria: a haplotypic view
The development and rapid spread of chloroquine resistance (CQR) in Plasmodium falciparum have triggered the identification of several genetic target(s) in the P. falciparum genome. In particular, mutations in the Pfcrt gene, specifically, K76T and mutations in three other amino acids in the region adjoining K76 (residues 72, 74, 75 and 76), are considered t
Mem. Inst. Oswaldo Cruz. Publicado em: 06/12/2013
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5. Herança da resistência da soja à podridão radicular de fitóftora, em variedades comerciais brasileiras
The phytophthora root rot (PRR), caused by Phytophthora sojae (Kaufman &Gerdman), is one of the most destructive soybean diseases and can provoke yield losses of up to 100%. PRR has occurred more frequently in Brazil since the season 2005/06, mainly in the South region. There are some resistant commercial varieties but their inheritance remains unknown. All
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/02/2012
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6. O papel modulador do receptor símile a TOLL 2 (TLR2) e da microbiota intestinal na sensibilidade e sinalização da insulina em camundongos / The modulatory role of the Toll-like receptor (TLR)2 and of the gut microbiota in the modulation of the insulin sensitivity and signaling
Environmental factors and host genetics interact to control the gut microbiota, which may have a role in the development of obesity and insulin resistance. TLR2 deficient mice, under germ-free conditions are protected from diet-induced insulin resistance. Diet-induced obese mice, acutely treated with TLR2 oligonucleotide antisense during 4 days showed increa
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/02/2012
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7. Genetics of leprosy reactions: an overview
Type-1 (T1R) and Type-2 (T2R) leprosy reactions (LR), which affect up to 50% of leprosy patients, are aggressive inflammatory episodes of sudden onset and highly variable incidence across populations. LR are often diagnosed concurrently with leprosy, but more frequently occur several months after treatment onset. It is not uncommon for leprosy patients to de
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-12
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8. Genetic approaches for studying transgene inheritance and genetic recombination in three successive generations of transformed tobacco
Transgene integration into plant genomes is a complex process accompanied by molecular rearrangements. Classic methods that are normally used to study transgenic population genetics are generally inadequate for assessing such integration. Two major characteristics of transgenic populations are that a transgenic genome may harbor many copies of the transgene
Genetics and Molecular Biology. Publicado em: 2012
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9. Simulação Computacional e Análise de um Modelo Fenotípico de Evolução Viral. / Computer Simulation and Analysis of a Phenotypic Model of Viral Evolution
A large amount of viruses of medical importance such as HIV, respiratory syncytial virus, the hepatitis C virus, influenza A (H1N1) and polio virus, has RNA genome. These viruses exhibit extremely high mutational rate, fast replicative kinetics, large population of particles and high genetic diversity. Manifested during the infectious process, these features
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/01/2011
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10. Molecular markers and genetic diversity of Plasmodium vivax
Enhanced understanding of the transmission dynamics and population genetics for Plasmodium vivax is crucial in predicting the emergence and spread of novel parasite phenotypes with major public health implications, such as new relapsing patterns, drug resistance and increased virulence. Suitable molecular markers are required for these population genetic stu
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-08
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11. Sequence analysis of coding DNA fragments of pfcrt and pfmdr-1 genes in Plasmodium falciparum isolates from Odisha, India
The global emergence and spread of malaria parasites resistant to antimalarial drugs is the major problem in malaria control. The genetic basis of the parasite's resistance to the antimalarial drug chloroquine (CQ) is well-documented, allowing for the analysis of field isolates of malaria parasites to address evolutionary questions concerning the origin and
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-02
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12. Interação molecular planta-nematóide.
ABSTRACT: The endoparasitic sedentary phytonematodes of genera Heterodera, Globodera (known as cyst nematodes, CN) and Meloidogyne (the root-knot nematodes, RKN) are major crop phytopathogens, causing estimated losses of US$ 125 billion annually in the world. These plant-parasitic nematodes share some parasitism mechanisms, which ensure host-tissue invasion
Planaltina. Publicado em: 2011