Genic Control
Mostrando 1-12 de 29 artigos, teses e dissertações.
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1. Effect of hyperbaric oxygenation on the expression of glutathione peroxidase 4 and lactoperoxidase genes in the lung of isogenic mice after ischemia/reperfusion injury in the small bowel
Abstract Purpose: To evaluate the effect of hyperbaric oxygenation (HBO) on the expression of the genes antioxidant glutathione peroxidase 4 (Gpx4) and lactoperoxidase (Lpo) in the lung of mice subjected to intestinal ischemia and reperfusion (IIR). Methods: Control group (CG) in which were subjected to anesthesia, laparotomy and observation for 120 minu
Acta Cir. Bras.. Publicado em: 2018-05
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2. Hyperbaric oxygenation and the genic expression related to oxidative stress in the heart of mice during intestinal ischemia and reperfusion
Abstract Purpose: To investigate the effects of hyperbaric oxygenation (HBO) on intestinal ischemia and reperfusion (IR) injury, we evaluated the expression of 84 genes related to oxidative stress and the antioxidant response in mouse hearts. Methods: Four groups were subjected to 60 minutes of intestinal ischemia followed by 60 minutes of reperfusion: IR
Acta Cir. Bras.. Publicado em: 2017-11
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3. Caracterização do gene LmHUS1 e de sua participação no fenômeno de amplificação gênica em Leishmania spp. / LmHUS1 gene characterization and its participation in the gene amplification in Leishmania spp.
The protozoan parasite Leishmania presents a dynamic and plastic genome in which gene amplification and chromosome translocations are common phenomena. Such plasticity hints at the necessity of dependable genome maintenance pathways. Eukaryotic cells have evolved checkpoint control systems that recognize altered DNA structures and halt cell cycle progression
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/09/2011
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4. Efeito da restrição protéica materna durante a lactação sobre a resposta de timócitos da prole jovem de ratos Wistar / Maternal protein deprivation during lactation increases leptin activity and inhibits apoptosis of thymic cells from young offspring
In this study, we investigated the consequences of maternal protein deprivation during lactation on thymocyte responses of the offspring Wistar rats (PD group) and the role of leptin in these alterations. Compared to group C, PD animals showed at 30 days of age, lower body and thymus weights, with no alteration in the thymocyte number or any difference in th
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/03/2011
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5. Mapping of quantitative trait loci for thermosensitive genic male sterility in indica rice.
The objective of this work was to select and use microsatellite markers, to map genomic regions associated with the genetic control of thermosensitive genic male sterility (TGMS) in rice. An F2 population, derived from the cross between fertile and TGMS indica lines, was used to construct a microsatellite-based genetic map of rice. The TGMS phenotype showed
Pesquisa Agropecuária Brasileira. Publicado em: 2011
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6. Estudo comparativo do efeito da Echinácea purpúrea e sorafenibe em células de adenocarcinoma renal humano em cultura / Comparative study of the effect of Echinacea purpurea and sorafenib in human renal adenocarcinoma cells in culture
Introduction: The renal cell carcinoma (CR) is relatively rare compared to other cancers. One of the most potent tumor mitogen, vascular endothelial growth factor, VEGF is regulated by numerous pathways, especially Ras and Akt, which are targets of many therapeutic agents, among them sorafenib. These signaling pathways play an important role in the developme
Publicado em: 2010
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7. Avaliação do estresse oxidativo, genotoxicidade e mutagenicidade em trabalhadores expostos a tintas
Organic solvents and metals, widely used in paints, can lead to DNA damages and reactives species (RS) generation. The aim of this study was to evaluate possibles oxidative, genotoxic and mutagenic damages in 33 male workers exposed for at least six months to paint. To constitute the control group 29 healthy individuals were choosen, without paint exposure,
Publicado em: 2009
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8. Genic expression alterations in the tolerance to LPS : B lymphocyte in the genic regulation of the tolerance / Alterações de expressão gênica na tolerância ao LPS: análise da participação dos linfócitos B na regulação gênica da tolerância
Sepses are caused by microorganisms such as: Gram-negative bacteria, Gram-positive bacteria, fungus and virus. Several sepses and the septic shock have been associated with the mortality rates from 40 to 60%. One of the most important events for the septic evolution is the apoptosis cells of the immune system. The cells immune system elimination compromises
Publicado em: 2008
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9. Toxicidade da polimixina B em células LLC-PK1 e a enzima heme oxigenase-1 / Polymyxin B toxicity in LLC-PK1 cells and the heme oxygenase-1 enzyme
In the acute kidney injury, the mechanisms of defense act as protector genes, as the protein heat shock 32 (HSP 32), also known as heme oxygenase-1 (HO-1). The polymyxin B (PmxB) is a nephrotoxic antimicrobial. The aim of this study was to distinguish the role of the HO-1 enzyme in the PmxB toxicity in LLC-PK1 cells. The cells were submitted to the following
Publicado em: 2008
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10. Estudo do sistema neuroimunoendócrino na caquexia neoplásica e da resposta ao tratamento com esteróides
The anorexia-cachexia syndrome (ACS), of multifactorial source and complex, is common in chronic diseases, like advanced cancer. Is associated with weight loss and decrease food intake, sometimes causing death. The objective of the present study was to evaluate the influence of neoplastic cachexia over the hypothalamus-pituitary-adrenal axis and immune syste
Publicado em: 2008
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11. POLIMORFISMO DO GENE TP53 EM SARCOMAS DE PARTES MOLES NO ADULTO
Soft tissue sarcomas (STS) are tumors with mesodermical origin, comprising about 1% of all adult neoplasms. Because of its effect on the p53 protein coding sequence, and its association with an increased risk for some cancer types, TP53 codon 72 polymorphism has been investigated in several studies. TP53 codon 72 codes for either Arginine (p53Arg), or Prolin
Publicado em: 2008
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12. Estudo in silico de genes que codificam fatores de transcriÃÃo responsivos Ãseca, salinidade e congelamento nos genomas do eucalipto, cana e arroz
Abiotic stresses are the most responsable for causing changes in plant growth and development. The plants, in counterpart, make use of a variety of responses in order to maintain their metabolic and physiological processes. One of the main plants responses to environmental conditions alterations is the additional regulation of expression. Moreover, the biosy
Publicado em: 2007