Genomic Ancestry
Mostrando 1-12 de 36 artigos, teses e dissertações.
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1. Association of breastfeeding, maternal anthropometry and body composition in women at 30 years of age
Este estudo teve por objetivo avaliar a associação entre aleitamento materno e índice de massa corporal (IMC), circunferência da cintura, índice de massa gorda, índice de massa magra, razão de gordura andróide/ginóide e densidade mineral óssea maternos. Em 1982, as maternidades de Pelotas, Rio Grande do Sul, Brasil, foram visitadas diariamente e to
Cad. Saúde Pública. Publicado em: 18/02/2019
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2. Growth hormone insensitivity with immune dysfunction caused by a STAT5B mutation in the south of Brazil: evidence for a founder effect
ABSTRACT Homozygous STAT5B mutations causing growth hormone insensitivity with immune dysfunction were described in 10 patients since 2003, including two Brazilian brothers from the south of Brazil. Our objectives were to evaluate the prevalence of their STAT5B mutation in this region and to analyze the presence of a founder effect. We obtained DNA samples f
Genet. Mol. Biol.. Publicado em: 05/06/2017
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3. Prevalence of IFNL3 gene polymorphism among blood donors and its relation to genomic profile of ancestry in Brazil
ABSTRACT The recent development of interferon-free regimens based on direct-acting antivirals for the treatment of chronic hepatitis C virus infection has benefited many but not all patients. Some patients still experience treatment failure, possibly attributed to unknown host and viral factors, such as IFNL3 gene polymorphism. The present study assessed the
Braz J Infect Dis. Publicado em: 2016-12
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4. Aproximaciones cientificas al mestizo mexicano
The colonial category of mestizo was an ideological tool that shaped national identity in the post-revolutionary period in Mexico. The Indian-mestizo axis functioned to organize the ethnic and political interactions of the state. Doctors and anthropologists reinforced this dual taxonomy in studies of human populations, using biomedical markers to produce dif
Hist. cienc. saude-Manguinhos. Publicado em: 2013-06
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5. Identificação de genes de suscetibilidade às fissuras labiopalatinas não sindrômicas: influência da epidemiologia e da estratificação populacional / Identification of susceptibility genes to nonsyndromic cleft lip/palate: epidemiology and population stratification influences
Fissura labial com ou sem fissura de palato não sindrômica (FL±P NS) é uma doença complexa que afeta 1:700 indivíduos no mundo. A busca das causas genéticas dessa malformação é dificultada pelo padrão multifatorial de herança e pela heterogeneidade genética, sendo que o gene IRF6 e a região 8q24 são os loci de associação mais corroborada. A
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/07/2011
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6. Application of an African Ancestry index as a genomic control approach in a brazilian population
Ten ancestry informative markers were investigated in 101 coronary artery disease patients and 102 healthy controls from a Southern Brazilian population, in order to determine if stratification occurs in this population. The degree of African admixture detected in this population was estimated to be as high as 6%, but no differences between cases and control
Publicado em: 2011
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7. Molecular studies of the Brazilian infectious bronchitis virus isolates
Avian infectious bronchitis virus (IBV) isolates have been widely characterized by reverse transcription followed by polymerase chain reaction and DNA sequencing. In present study, these techniques were applied to three viral genomic regions comprising the complete and/or a partial S1 segment, S2 and nucleocapsid genes. DNA sequences from viral isolates obta
Revista Brasileira de Ciência Avícola. Publicado em: 2010-06
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8. Estudo associativo entre fatores de risco cardiovascular e genótipos de 11 mediadores inflamatórios independentes controlado para ancestralidade genômica em amostra de mulheres idosas brasileiras / Associative study between cardiovascular risk factors and genotypes of 11 independent inflamatory mediators controlled for genomic ancestry in Brazilian older women / Associative study between cardiovascular risk factors and genotypes of 11 independent inflamatory mediators controlled for genomic ancestry in Brazilian older women / Estudo associativo entre fatores de risco cardiovascular e genótipos de 11 mediadores inflamatórios independentes controlado para ancestralidade genômica em amostra de mulheres idosas brasileiras
Objetivo: Investigar a associação entre genótipos de mediadores inflamatórios e o estado de saúde de mulheres idosas expresso por fatores de risco cardiovascular clássicos na população brasileira. Materiais e métodos: Estudo transversal com amostra de conveniência constituída por 259 indivíduos com idade igual ou superior a 60 anos, do sexo femin
Publicado em: 2010
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9. DNA tests probe the genomic ancestry of Brazilians
We review studies from our laboratories using different molecular tools to characterize the ancestry of Brazilians in reference to their Amerindian, European and African roots. Initially we used uniparental DNA markers to investigate the contribution of distinct Y chromosome and mitochondrial DNA lineages to present-day populations. High levels of genetic ad
Brazilian Journal of Medical and Biological Research. Publicado em: 11/09/2009
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10. Color and genomic ancestry in Brazilians
This work was undertaken to ascertain to what degree the physical appearance of a Brazilian individual was predictive of genomic African ancestry. Using a panel of 10 population-specific alleles, we assigned to each person an African ancestry index (AAI). The procedure was able to tell apart, with no overlaps, 20 males from northern Portugal from 20 males fr
The National Academy of Sciences.
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11. Genomics and chloroplast evolution: what did cyanobacteria do for plants?
Plant chloroplast originated, through endosymbiosis, from a cyanobacterium, but the genomic legacy of cyanobacterial ancestry extends far beyond the chloroplast itself, and persists in organisms that have lost chloroplasts completely.
BioMed Central.
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12. Extent and Distribution of Linkage Disequilibrium in Three Genomic Regions
The positional cloning of genes underlying common complex diseases relies on the identification of linkage disequilibrium (LD) between genetic markers and disease. We have examined 127 polymorphisms in three genomic regions in a sample of 575 chromosomes from unrelated individuals of British ancestry. To establish phase, 800 individuals were genotyped in 160
The American Society of Human Genetics.