Gingival Overgrowth
Mostrando 1-12 de 24 artigos, teses e dissertações.
-
1. Effects of cyclosporin, nifedipine and phenytoin on gingival myofibroblast transdifferentiation in monkeys
Abstract Objective: Myofibroblasts have been associated with the development of several pathologic fibrotic conditions. This longitudinal study aims to assess the proliferative and antiapoptotic effects of cyclosporin, nifedipine and phenytoin on gingival connective tissue cells of nonhuman primate, as well as to analyze a possible role of myofibroblasts in
J. Appl. Oral Sci.. Publicado em: 08/11/2018
-
2. Phenytoin-Induced Gingival Overgrowth Management with Periodontal Treatment
O crescimento gengival induzido pela fenitoína é uma complicação comum do uso contínuo da medicacão. Este artigo apresenta um caso de crescimento gengival excessivo que dificultava a função oral e comprometia a higiene oral e a estética, o qual foi tratado com uma combinação de terapias periodontais nã
Braz. Dent. J.. Publicado em: 2015-02
-
3. Eventos moleculares associados ao aumento gengival induzido por ciclosporina A são atenuados pela superexpressão de Smad7 / Molecular events associated with cyclosporin A induced gingival overgrowth are attenuated by Smad 7 overexpression
O aumento gengival induzido por ciclosporina A (CsA) é causado por um acúmulo excessivo de matriz extracelular, resultado da ação do fator de crescimento transformante-beta 1 (TGF-ß1) sobre a atividade dos fibroblastos gengivais. O presente estudo investigou in vitro os efeitos da superexpressão de Smad7, um inibidor da sinalização de TGF-ß1, nos ev
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/07/2011
-
4. Low prevalence of gingival overgrowth associated to new imunossupressive protocols with cyclosporin
Gingival overgrowth (GO) is a frequent finding in patients treated with cyclosporine (CsA). This study investigated the prevalence and severity of GO in patients who received kidney transplant and CsA therapy, as well as associations with pharmacological and clinical factors. This cross-sectional study included 63 kidney transplant recipients who were treate
Brazilian Oral Research. Publicado em: 01/12/2011
-
5. Cyclosporin A-induced gingival overgrowth is not associated with myofibroblast transdifferentiation
Cyclosporin A (CyA) induces gingival overgrowth via its stimulatory effects on expression of transforming growth factor-beta1 (TGF-β1) and collagen. It is not known whether CyA has a direct effect on gingival fibroblasts or induces its effect indirectly via stimulation of myofibroblast transdifferentiation. The present study was undertaken to examine the in
Brazilian Oral Research. Publicado em: 2010-06
-
6. Influence of diltiazem in combination with a sucrose-rich diet on gingival alterations in rats
The aim of this study was to evaluate the influence of diltiazem in combination with a sucrose-rich diet on gingival alterations in rats. One hundred and twenty male Holtzman rats were randomly assigned to 10 groups (n = 12), being 2 control groups treated with saline and 8 test groups treated with diltiazem in daily doses of 5, 25, 50 and 100 mg/kg during 4
Brazilian Oral Research. Publicado em: 2009-03
-
7. Evaluation clinical and microbiological of oral health conditions in renal transplant recipients of Onofre Lopes University Hospital, Natal RN / Avaliação clínica e microbiológica das condições de saúde oral dos receptores de transplante renal do Hospital Universitário Onofre Lopes, Natal RN
Introduction: The chronic immunosuppression promotes the development of changes in the oral cavity of the kidney transplant recipients (KTR), however with the exception of gingival overgrowth, little is known regarding the prevalence of oral lesions in this population. Objective: To evaluate the prevalence of clinical and microbiological conditions of the or
Publicado em: 2009
-
8. Variáveis de risco associadas ao crescimento gengival em indivíduos transplantados renais sob os regimes imunossupressores de ciclosporina, tacrolimus e sirolimus
Studies regarding gingival overgrowth (GO) and its associated risk factors in renal transplant recipients under cyclosporine A (CsA) and tacrolimus (Tcr) imunosuppressive regimens have shown conflicting findings and there is no available data regarding sirolimus (Sir). Therefore, the present study wich is displayed as a review of literature and 3 scientific
Publicado em: 2009
-
9. Indução de doença periodontal em ratos previamente expostos à ciclosporina A
A Ciclosporina A (CsA) é o medicamento de escolha utilizado no controle da rejeição de órgãos em pacientes transplantados. Efeitos adversos associados ao fármaco, como alterações ósseas e o aumento gengival são fatores de risco para a doença periodontal. O objetivo do estudo foi avaliar o efeito da indução de doença periodontal no tecido ósseo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/08/2008
-
10. Analise dos efeitos e dos mecanismos de ação do fator de crescimento transformante- beta 1, interferon gama e iclosporina A na transdiferenciação dos fibroblastos gengivais em miofibroblastos / Effects of transforming growth factor- beta 1, interferon gamma and cyclosporin A on transdifferentiation of gingival fibroblasts in myofibroblasts
Myofibroblasts are the main cellular type involved in extracellular matrix deposition in fibrotic diseases. Relatively little is known about the underlying mechanisms that regulate myofibroblast emergence (transdifferentiation), however the regulatory cytokine transforming growth factor-beta 1 (TGF- beta 1) has been traditionally considered an inducer of the
Publicado em: 2007
-
11. Perfil periodontal de pacientes portadores de alterações endócrino-metabólicas
Objective- Convinced that periodontium, many times, can show alterations in human health, the aim of these studies was to investigate the periodontal situation in patients with endocrine-metabolic disorders such as, Berardinelli-Seip Syndrome, hyperthyroidism, hypothyroidism and acromegaly. Methods- Eight patients with Berardinelli-Seip Syndrome, 16 acromega
Publicado em: 2007
-
12. In situ hibridization for Epstein-Barr virus (EBV) and Human Papiloma virus in drug-induced gingival overgrowth in renal transplantation patients / Identificação do vírus Epstein-Barr (EBV) e do papiloma vírus humano (HPV) através da técnica de hibridização in situ em hiperplasias gengivais medicamentosas de pacientes transplantados renais
A fim de prevenir a rejeição do órgão transplantado pelo hospedeiro, se faz necessário o uso de drogas imunossupressoras, como a ciclosporina, que pode levar ao aparecimento de efeitos colaterais como hipertensão arterial, nefrotoxicidade, hepatotoxicidade, e hiperplasia gengival medicamentosa (HGM), que pode ser potencializada se bloqueadores de canal
Publicado em: 2007