Goblet Cell Hyperplasia
Mostrando 1-12 de 20 artigos, teses e dissertações.
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1. Efeitos das emissões geradas pela queima dos canaviais sobre a superfície ocular / Effects of sugar cane burning emissions on the ocular surface
The adverse effects of particle emissions produced by sugar cane burning represent a problem that affects mostly developing countries. Previous studies have shown that, during the burning period, there is an increase in respiratory hospital admissions and emergency room visits in communities surrounded by sugar cane plantations in rural cities of Brazil. How
Publicado em: 2010
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2. Effects of sugar cane burning emissions on the ocular surface / Efeito da talidomida na expressão e síntese dos proteoheparans sulfato de superfície celular em linhagens de mieloma múltiplo
Efeitos adversos das emissões geradas pela queim a da cana de açúcar representa um problema que afeta principalmente os países em desenvolvimento. Estudos prévios têm demonstrado que, durante o período de queima, há um aumento das admissões hospitalares e atendimentos de emergência nas cidades do Brasil próximas às plantações de cana. Entretant
Publicado em: 2006
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3. Absence of Proteinase-Activated Receptor-1 Signaling in Mice Confers Protection from fMLP-Induced Goblet Cell Metaplasia
The morphological features of chronic obstructive pulmonary disease in man include emphysema and chronic bronchitis associated with mucus hypersecretion. These alterations can be induced in mice by a single intratracheal instillation of N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP), a chemoattractant and degranulating agent for neutrophils. The mechan
American Thoracic Society.
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4. Effect of extremes of temperature and humidity on the goblet cell count in the rat airway epithelium
Jones, R., Baetjer, A. M., and Reid, L. (1971).Brit. J. industr. Med.,28, 369-373. Effect of extremes of temperature and humidity on the goblet cell count in the rat airway epithelium. To investigate the effect of environmental temperature and humidity on the goblet cells in the rat airway epithelium, eight animals were exposed for four to five weeks to each
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5. Epidermal growth factor system regulates mucin production in airways
Goblet-cell hyperplasia is a critical pathological feature in hypersecretory diseases of airways. However, the underlying mechanisms are unknown, and no effective therapy exists. Here we show that stimulation of epidermal growth factor receptors (EGF-R) by its ligands, EGF and transforming growth factor α (TGFα), causes MUC5AC expression in airway epitheli
The National Academy of Sciences.
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6. A comparison of changes in the mucous glands and goblet cells of nasal, sinus, and bronchial mucosa
A comparison of mucous gland size in the bronchial and nasal mucosa was performed on material from 24 random necropsies. The Reid index and counts of mucous gland acini were used as measures of hypertrophy. In 14 of these cases the relationship between goblet cell hyperplasia in the sinus mucosa and the presence of chronic bronchitis was investigated by comp
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7. Modulation of Intestinal Muscle Contraction by Interleukin-9 (IL-9) or IL-9 Neutralization: Correlation with Worm Expulsion in Murine Nematode Infections
Immune responses associated with intestinal nematode infections are characterized by the activation of T-helper 2 (Th2) cells. Previous studies demonstrated that during Trichinella spiralis infection, Th2 cells contribute to the development of intestinal muscle hypercontractility and to worm eviction from the gut, in part through signal transducer and activa
American Society for Microbiology.
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8. Occupational exposure to formaldehyde and histopathological changes in the nasal mucosa.
To study the cytotoxic effect of formaldehyde on the human nasal mucosa 75 men with occupational exposure to formaldehyde or to formaldehyde and wood dust, were examined, looking particularly at early signs of irritative effects and histopathological changes in the nasal mucosa. All men underwent a medical examination and a nasal biopsy specimen was examined
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9. Comparison of human bronchiolar smooth muscle responsiveness in vitro with histological signs of inflammation.
A study was carried out to test the hypothesis that chronic inflammation is associated with increased sensitivity or contractility of human airway smooth muscle. Bronchiolar strips from 30 patients, 12 of whom had chronic bronchitis, were examined in the organ bath for their responses to histamine, methacholine, and leukotriene (LT) C4. The same airways were
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10. Responses of Well-Differentiated Airway Epithelial Cell Cultures from Healthy Donors and Patients with Cystic Fibrosis to Burkholderia cenocepacia Infection
Well-differentiated cultures established from airway epithelia of patients with cystic fibrosis (CF cultures) exhibited goblet cell hyperplasia, increased secretion of mucus, and higher basal levels of interleukin-8 than similarly cultured cells from healthy donors. Upon apical infection with low doses (104 to 105 CFU) of Burkholderia cenocepacia isolate BC7
American Society for Microbiology.
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11. Viral induction of a chronic asthma phenotype and genetic segregation from the acute response
Paramyxoviral infections cause most of the acute lower respiratory tract illness in infants and young children and predispose to the development of chronic wheezing, but the relationship between these short- and long-term viral effects are uncertain. Here we show that a single paramyxoviral infection of mice (C57BL6/J strain) not only produces acute bronchio
American Society for Clinical Investigation.
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12. Surfactant protein C-deficient mice are susceptible to respiratory syncytial virus infection
Patients with mutations in the pulmonary surfactant protein C (SP-C) gene develop interstitial lung disease and pulmonary exacerbations associated with viral infections including respiratory syncytial virus (RSV). Pulmonary infection with RSV caused more severe interstitial thickening, air space consolidation, and goblet cell hyperplasia in SP-C-deficient (S
American Physiological Society.