Guinea Pigs
Mostrando 1-12 de 1406 artigos, teses e dissertações.
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1. In vivo methods for the evaluation of anti-inflammatory and antinoceptive potential
RESUMO JUSTIFICATIVA E OBJETIVOS: A busca constante por compostos bioativos com atividade anti-inflamatória e antinociceptiva são de interesse dos centros de pesquisas. Para a caracterização dessas atividades são necessários ensaios em cobaias. Frente a isso, o objetivo deste estudo foi demonstrar alguns métodos para a avaliação do potencial anti-i
BrJP. Publicado em: 02/12/2019
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2. The Effects of Riluzole on Cisplatin-induced Ototoxicity
Abstract Introduction Riluzole (2-amino-6-trifluoromethoxy benzothiazole) is known as a neuroprotective, antioxidant, antiapoptotic agent. It may have beneficial effects on neuronal cell death due to cisplatin-induced ototoxicity. Objective To evaluate the effect of riluzole on cisplatin-induced ototoxicity in guinea pigs. Methods Twenty-four guinea pi
Int. Arch. Otorhinolaryngol.. Publicado em: 07/10/2019
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3. Development of the urinary system in guinea pig females (Cavia porcellus)
RESUMO: Os porquinhos-da-índia são modelos animais amplamente utilizados em pesquisas relacionadas a biologia do desenvolvimento. O objetivo deste trabalho foi demonstrar o processo de formação e diferenciação dos órgãos urinários em fêmeas da espécie no período pré-natal. Foram utilizadas quatro fêmeas aos 25, 30, 45 e >65 DG (dias de gestaç�
Pesq. Vet. Bras.. Publicado em: 30/09/2019
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4. Effect of Lavandula dentata extract on Ovalbumin-induced Asthma in Male Guinea Pigs
Resumo A asma é uma doença inflamatória dos pulmões e causa estresse oxidativo. Lavandula dentata é uma erva aromática com atividades anti-oxidantes e antiinflamatórias. Este estudo examinou a atividade do extrato de L. dentata em um modelo de asma de cobaia. Os machos adultos foram divididos em cinco grupos: o primeiro grupo foi controle, o segundo
Braz. J. Biol.. Publicado em: 18/04/2019
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5. Artificial blood feeding for Culicidae colony maintenance in laboratories: does the blood source condition matter?
ABSTRACT Culicidae colonization in laboratory is paramount to conduct studies aiming at a better understanding of mosquitoes' capacity to transmit pathogens that cause deadly diseases. Colonization requires female blood feeding, a necessary step for maturation of female's oocytes. Direct blood feeding on anesthetized mammals implies in a number of disadvanta
Rev. Inst. Med. trop. S. Paulo. Publicado em: 13/09/2018
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6. The Effects of Experimental Intratympanic Steroid Administration on Organ of Corti Type 1 Spiral Ganglion
Abstract Introduction It is unclear how effective is the intratympanic (IT) steroid treatment on organ of Corti type 1 spiral ganglion, its optimal dosage and frequency of administration. The effect of dexamethasone on cochlear functions in individuals with a normal hearing ability is also unknown. Objective The aim of this study was to evaluate, at the
Int. Arch. Otorhinolaryngol.. Publicado em: 2018-06
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7. New strategy to improve quality control of Montenegro skin test at the production level
Abstract INTRODUCTION: The production of the Montenegro antigen for skin test poses difficulties regarding quality control. Here, we propose that certain animal models reproducing a similar immune response to humans may be used in the quality control of Montenegro antigen production. METHODS: Fifteen Cavia porcellus (guinea pigs) were immunized with Leishm
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-12
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8. The quantification of testicular cells during the postnatal development in two Caviomorph rodents: the guinea pig (Cavia porcellus) and the cutia (Dasyprocta agouti)
ABSTRACT The germinative, Sertoli and Leydig cells of two caviomorph rodents (Cavia porcellus and Dasyprocta agouti) were counted as well as the estimation of the total volume of the testis and the total volume of seminiferous tubules and interstitium in prepubertal, pubertal and adult animals. The number of spermatogonia, spermatocytes and spermatids cells
An. Acad. Bras. Ciênc.. Publicado em: 17/08/2017
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9. Transplantation and survival of mouse inner ear progenitor/stem cells in the organ of Corti after cochleostomy of hearing-impaired guinea pigs: preliminary results
In mammals, damage to sensory receptor cells (hair cells) of the inner ear results in permanent sensorineural hearing loss. Here, we investigated whether postnatal mouse inner ear progenitor/stem cells (mIESCs) are viable after transplantation into the basal turns of neomycin-injured guinea pig cochleas. We also examined the effects of mIESC transplantation
Braz J Med Biol Res. Publicado em: 18/03/2016
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10. Effect of propranolol on capsular reaction around silicone implants in guinea pigs
PURPOSE: To evaluate the effect of propranolol on capsular architecture around silicone implants by measuring the inflammation, capsular thickness, and collagen fiber density, using a guinea pig experimental model.METHODS:Thirty six adult male guinea pigs randomly divided into two groups (n=18) were used. Each one received a silicone implant with textured-su
Acta Cir. Bras.. Publicado em: 2015-01
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11. The preventive effects of natural adjuvants, G2 and G2F on tracheal responsiveness and serum IL-4 and IFN-γ (th1/th2 balance) in sensitized guinea pigs
OBJECTIVE:The effects of natural adjuvants on lung inflammation and tracheal responsiveness were examined in sensitized guinea pigs.METHODS:The responses of guinea pig tracheal chains and the serum levels of interleukin-4 and interferon-gamma were examined in control pigs and three other groups of guinea pigs: the sensitized group and two other sensitized gr
Clinics. Publicado em: 2014-07
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12. Biocompatibility of Ricinus communis polymer with addition of calcium carbonate compared to titanium. Experimental study in guinea pigs
Objetivo: Determinar se a reação tecidual do implante retroperitoneal do polímero de óleo de mamona com acréscimo de carbonato de cálcio (Pm+CaCO3) é significativa, por meio de análise histopatológica, tendo como controle o implante de titânio não tratado (Ti). Métodos: Estudo experimental, intervencionista e randomizado com 32 cobaias. Os ani
Braz. J. Cardiovasc. Surg.. Publicado em: 2014-04