Hhex
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Expression of homeobox genes in oral squamous cell carcinoma cell lines, stimulated with EGF and TGF-beta / Expressão de genes homeobox em células de carcinoma epidermóide de boca estimuladas com EGF e TGF-beta
Homeobox genes, vital to many aspects related with cellular growth and differentiation, had been described as deregulated in some cancers. Their role in carcinogenesis, mainly oral squamous cell carcinomas, remains unclear and poorly characterized. Thus, this study had the purpose to evaluate, in cell cultures, the expression profile of six homeobox genes (A
Publicado em: 2008
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2. Estudo da expressão dos genes HOXB13 e HHEX em carcinomas epidermóides de boca através das técnicas de RT-PCR e Hibridização in situ. / HOXB13 and HHEX expression study in oral squamous cell carcinoma with the RT-PCR and in situ Hybridization techniques.
The aim of this study was to verify the HOXB13 and HHEX genes expression in oral squamous cell carcinoma (OSCC) using Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) and in situ Hybridization techniques. Tumoral tissues and adjacent non-tumoral oral mucosa specimens were obtained from 30 patients with OSCC at the Head and Neck Surgery Service HC (FM
Publicado em: 2004
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3. Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming
Therapeutic regulation of globin genes is a primary goal of translational research aimed toward hemoglobinopathies. Signal transduction was used to identify chromatin modifications and transcription factor expression patterns that are associated with globin gene regulation. Histone modification and transcriptome profiling were performed using adult primary C
American Society of Hematology.
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4. Folate rescues lithium-, homocysteine- and Wnt3A-induced vertebrate cardiac anomalies
Elevated plasma homocysteine (HCy), which results from folate (folic acid, FA) deficiency, and the mood-stabilizing drug lithium (Li) are both linked to the induction of human congenital heart and neural tube defects. We demonstrated previously that acute administration of Li to pregnant mice on embryonic day (E)6.75 induced cardiac valve defects by potentia
The Company of Biologists Limited.