Hippocampus And Amygdala
Mostrando 1-12 de 107 artigos, teses e dissertações.
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1. Systemic injection of an H4 receptor agonist induces a decrease in CREB and pCREB levels in the cerebellar vermis and prefrontal cortex in mice
Studies have shown that an injection with the histamine H4 receptor agonist VUF-8430 modulates emotional memory processes. In the present study, the aim was to verify if intraperitoneal (ip) injection of VUF-8430 (500 ng/kg) in mice affects the synthesis of proteins required for memory consolidation processes by activating the phosphorylation of CREB (pCREB)
Braz J Med Biol Res. Publicado em: 25/04/2019
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2. Erratum: Brain Region Specificity of Mitochondrial Biogenesis and Bioenergetics Response to Nrf2 Knockdown: A Comparison Among Hippocampus, Prefrontal Cortex and Amygdala of Male Rat Brain
Braz. arch. biol. technol.. Publicado em: 06/12/2018
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3. Smaller left anterior cingulate cortex in non-bipolar relatives of patients with bipolar disorder
Objective: Bipolar disorder (BD) is highly heritable. The present study aimed at identifying brain morphometric features that could represent markers of BD vulnerability in non-bipolar relatives of bipolar patients. Methods: In the present study, structural magnetic resonance imaging brain scans were acquired from a total of 93 subjects, including 31 patie
Braz. J. Psychiatry.. Publicado em: 06/12/2018
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4. Adrenergic receptor β3 is involved in the memory consolidation process in mice
Attention and emotion have a positive impact on memory formation, which is related to the activation of the noradrenergic system in the brain. The hippocampus and amygdala are fundamental structures in memory acquisition, which is modulated by noradrenaline through the noradrenergic receptors. Pharmacological studies suggest that memory acquisition depends o
Braz J Med Biol Res. Publicado em: 06/08/2018
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5. Brain Region Specificity of Mitochondrial Biogenesis and Bioenergetics Response to Nrf2 Knockdown: A Comparison Among Hippocampus, Prefrontal Cortex and Amygdala of Male Rat Brain
ABSTRACT Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) has been identified as the well-known coordinator of intracellular antioxidant defense system. Herein, we aimed to evaluate the effects of Nrf2 silencing on mitochondrial biogenesis markers peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), nuclear respiratory factor-1(N
Braz. arch. biol. technol.. Publicado em: 17/08/2017
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6. Ketamine alters behavior and decreases BDNF levels in the rat brain as a function of time after drug administration
Objective: To evaluate behavioral changes and brain-derived neurotrophic factor (BDNF) levels in rats subjected to ketamine administration (25 mg/kg) for 7 days. Method: Behavioral evaluation was undertaken at 1 and 6 hours after the last injection. Results: We observed hyperlocomotion 1 hour after the last injection and a decrease in locomotion after 6
Rev. Bras. Psiquiatr.. Publicado em: 2013-09
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7. The impacts of cognitive-behavioral therapy on the treatment of phobic disorders measured by functional neuroimaging techniques: a systematic review
Objective: Functional neuroimaging techniques represent fundamental tools in the context of translational research integrating neurobiology, psychopathology, neuropsychology, and therapeutics. In addition, cognitive-behavioral therapy (CBT) has proven its efficacy in the treatment of anxiety disorders and may be useful in phobias. The literature has shown t
Rev. Bras. Psiquiatr.. Publicado em: 2013-09
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8. Estudo da associação entre atrofia de estruturas limbicas, depressão e epilepsia de lobo temporal mesial / Study of association between atrophy of limbic structures, depression and mesial temporal lobe epilepsy
Depression has been one of the most commonly related mental disorders associated with MTLE, reaching approximately 20% to 55% of the cases, whereas its prevalence is 9% in the general population. Since the aspects that interact in the association MTLE-depression are still quite fragmented, the physiopathology of depression in MTLE is not fully understood. Th
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/02/2012
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9. Maternal separation during breastfeeding induces changes in the number of cells immunolabeled to GFAP
The mother-child relationship is fundamental to the establishment and maintenance of synaptic networks and physiological and emotional development. Animal models including maternal separation have been used to study changes at behavioral and neurobiochemical levels. Due to the relevance of glial cells during development, our aim was to determine if short per
Psychol. Neurosci.. Publicado em: 2012-12
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10. A participação de diferentes sistemas neuromodulatórios no hipocampo, núcleo basolateral da amígdala e córtex pré-frontal ventromedial na extinção de memórias aversivas
Extinction consists of the learned inhibition of retrieval of previously acquired memory. Many forms of learning are modulated by ¿-noradrenergic, D1-dopaminergic and H2-histaminergic receptors on ventromedial prefrontal cortex (vmPFC), basolateral amygdala (BLA) and dorsal hippocampus. Therefore, the aim of this work was investigated the modulation of aver
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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11. Efeito ansiolítico do ondansetron, antagonista dos receptores 5-HT3, injetado na amídala de camundongos submetidos à exposição e reexposição no labirinto em cruz elevado
Against of stimuli that are dangerous, animals manifest defense reactions that cause fear and anxiety. These stimuli activate the serotonergic system, which sends projections to structures involved in defense mechanisms such as the septum, hypothalamus, hippocampus, amygdala and periaqueductal gray modulates the behavioral changes that can be characterized a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2011
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12. Estudo translacional sobre a qualidade do cuidado materno em resposta ao estresse neonatal, sua associação com ansiedade na vida adulta e investigação de potenciais mecanismos envolvidos
Introduction: In humans, there is the suggestion that an adverse early life environment is related to the development of anxiety disorders in adulthood. This association could potentially be mediated by stress responses, brain-derived neurotrophic factor (BDNF) and by neuronal nitric oxide synthase (nNOS). This study aimed at proposing an animal model for th
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011