Histopathological Biomarkers
Mostrando 1-12 de 18 artigos, teses e dissertações.
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1. CD45RO+TILs: cellular biomarkers for larynx squamous cell carcinoma outcome
Abstract Objective: The prognostic importance of Tumor-Infiltrating Lymphocytes (TILs) in the tumor microenvironment of various cancers is increasingly recognized. In the present study, we aimed to investigate the prognostic value of CD3+, CD4+, CD8+, and CD45RO + TILs and their relation to histopathological features in larynx squamous cell carcinoma. Meth
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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2. Impact of Anthropogenic Activities on Water Quality of The Paranhana River, Southern Brazil
Abstract: The Paranhana River, located in Southern Brazil, is one of the major tributaries of the Sinos River basin and receives mainly industrial and domestic effluents. In the present study, water physicochemical and microbiological analyses, condition factor, micronucleus test, gill histopathology and metal bioaccumulation in the muscle of the native fish
Braz. arch. biol. technol.. Publicado em: 25/11/2019
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3. Alcesefoliside protects against oxidative brain injury in rats
ABSTRACT This study investigated the possible antioxidant and neuroprotective effects of alcesefoliside, isolated from Astragalus monspessulanus L., Fabaceae, against carbon tetrachloride (CCl4)-induced brain injury in Wistar rats. Iron sulphate/ascorbic acid lipid peroxidation was induced in rat brain microsomes and pre-incubated with alcesefoliside and sil
Rev. bras. farmacogn.. Publicado em: 27/05/2019
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4. Formulation and evaluation of topical herbal gel for the treatment of arthritis in animal model
ABSTRACT The objective of the study is to formulate and evaluate a topical herbal gel containing Cardiospermum halicacabum and Vitex negundo leaf extracts for their anti-arthritic activity in rats. Twelve herbal gel formulations were prepared using 1.5% of gelling agents carbopol 934 (F1-F6) and carbopol 940 (F6-F12) and they were evaluated for physical appe
Braz. J. Pharm. Sci.. Publicado em: 2016-09
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5. Effect of hypertonic saline treatment on the inflammatory response after hydrochloric acid-induced lung injury in pigs
OBJECTIVES:Hypertonic saline has been proposed to modulate the inflammatory cascade in certain experimental conditions, including pulmonary inflammation caused by inhaled gastric contents. The present study aimed to assess the potential anti-inflammatory effects of administering a single intravenous dose of 7.5% hypertonic saline in an experimental model of
Clinics. Publicado em: 2015-08
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6. Toll-like receptor 3 gene polymorphisms are not associated with the risk of hepatitis B and hepatitis C virus infection
INTRODUCTION: The present study investigated the prevalence of two single-nucleotide polymorphisms (SNPs) in the Toll-like receptor 3 (TLR3) gene in patients infected with hepatitis B virus (HBV) and hepatitis C virus (HCV). METHODS: Samples collected from HCV (n = 74) and HBV (n = 35) carriers were subjected to quantitative real-time PCR (qPCR) to detect t
Rev. Soc. Bras. Med. Trop.. Publicado em: 2015-04
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7. Biomarcadores comportamentais, histopatológicos e proteômicos da toxicidade aguda da formulação comercial do herbicida glifosato em poecilia reticulata / Behavioral biomarkers, histopathological, and proteomic acute toxicity of the commercial formulation of glyphosate in Poecilia reticulata
O mecanismo de toxicidade aguda da formulação comercial de glifosato, Roundup Transorb (RDT), foi investigado para as brânquias do guaru (Poecilia reticulata) por meio de tecnologias proteômicas associadas às análises dos índices histopatológicos (HIs), seguido da quantificação das lesões histopatológicas branquiais. Além disso, o presente traba
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/02/2012
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8. Toxicidade aguda e respostas metabólicas e hematológicas do pacu (Piaractus mesopotamicus, Holmberg, 1887) exposto a concentração sub-letal de triclorfon e recuperação
Parasitosis in fishes is a relevant problem in aquaculture. Besides, the organophosphate trichlorfon (2,2,2-trichloro-1-hydroxyethyl phosphonate) is amongst the most used medicine in farming of fishes. Due to trichlorfon use in fish parasitosis control, including pacu (Piaractus mesopotamicus), in brazilian and worldwide aquaculture, it is necessary to study
Publicado em: 2010
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9. Study of the effects of naphthalene and benzo(a) pyrene in Trachinotus carolinus (Perciformes, Carangidae) using citogenotoxic, histopahological and biochemical biomarkers. / Estudo sobre efeitos do naftaleno e benzo(a) pireno em Trachinotus carolinus (Perciformes, Carangidae) utilizando biomarcadores citogenotóxicos, histopatológicos e bioquímicos
Effects of exposure of fish to pollutants can be identified through stress responses. The present study aims to evaluate the effects of naphthalene and benzo(a)pyrene in Florida pompanos, Trachinotus carolinus. Evidences from citogenotoxical, histopathological and biochemical studies showed that alterations caused by exposures to 0.9 M, 2.7 M and 8.1 M of NA
Publicado em: 2009
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10. Indicadores ecológicos e biomarcadores de contaminação ambiental na ictiofauna da baía de Santos e do canal de Bertioga, São Paulo, Brasil / Ecological indicators and biomarkers of environmental contamination of Ichthyofauna at Santos bay and Bertioga channel, São Paulo, Brazil
Este trabalho teve como objetivo analisar três métodos de avaliação de contaminação ambiental, sendo dois aplicados em um modelo biológico, a espécie Achirus lineatus (Achiridae, Pleuronectiformes) e o terceiro na ictiofauna da baía de Santos e do canal de Bertioga. As amostras foram coletadas mensalmente no ano de 2005 utilizando-se uma rede de arr
Publicado em: 2009
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11. Carcinoma ductal invasivo mamÃrio esporÃdico: uma abordagem histoquÃmica e imunohistiquÃmica
Breast cancer is the most frequent neoplasia and the main cause of cancer death in women worldwide. Among the several types of mammary gland neoplasia Invasive Ductal Carcinoma (IDC) represents 65% to 80% of all carcinomas. The major problem concerning this neoplasia is the great genotypic and phenotypic heterogeneity. This feature explains the increasing se
Publicado em: 2009
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12. Marcadores moleculares, imunológicos e genéticos das reações hansênicas / Molecular markers, genetic and immunological reactions of leprosy
Type 1 (T1R) and Type 2 (T2R) leprosy reactions are complications in the clinical management of leprosy patients because they can lead to neural damage and impairment, resulting in irreversible deformities and disabilities. This thesis, presented as research article/manuscript has investigated potential markers for the diagnosis and prognosis of leprosy reac
Publicado em: 2009