Hiv 1 Primary Drug Resistance
Mostrando 1-12 de 48 artigos, teses e dissertações.
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1. Primary bacillary resistance in multidrug-resistant tuberculosis and predictive factors associated with cure at a referral center in São Paulo, Brazil
RESUMO Objetivo: Identificar resistência transmitida ou primária entre casos de tuberculose multidrogarresistente e fatores preditivos associados à cura da tuberculose multidrogarresistente após o primeiro tratamento. Método: Estudo descritivo de uma coorte de 2006 a 2010, em uma unidade de referência em tuberculose no estado de São Paulo, Brasil. O
J. bras. pneumol.. Publicado em: 11/03/2019
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2. Computational drug design strategies applied to the modelling of human immunodeficiency virus-1 reverse transcriptase inhibitors
Reverse transcriptase (RT) is a multifunctional enzyme in the human immunodeficiency virus (HIV)-1 life cycle and represents a primary target for drug discovery efforts against HIV-1 infection. Two classes of RT inhibitors, the nucleoside RT inhibitors (NRTIs) and the nonnucleoside transcriptase inhibitors are prominently used in the highly active antiretrov
Mem. Inst. Oswaldo Cruz. Publicado em: 2015-11
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3. Assessing subtypes and drug resistance mutations among HIV-1 infected children who failed antiretroviral therapy in Kelantan, Malaysia
Antiretroviral (ARV) therapy has dramatically reduced morbidity and mortality in human immunodeficiency virus 1 (HIV-1) infected children. However, development of ARV resistance in these children is a major public health problem due to lack of availability of and access to new drugs. This study was conducted in order to identify circulating HIV subtypes and
Brazilian Journal of Infectious Diseases. Publicado em: 2012-06
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4. Primary resistance of HIV to antiretrovirals among individuals recently diagnosed at voluntary counselling and testing centres in the metropolitan region of Recife, Pernambuco
Determining the prevalence and type of antiretroviral (ARV) resistance among ARV-naïve individuals is important to assess the potential responses of these individuals to first-line regimens. The prevalence of primary resistance and the occurrence of recent infections among individuals with human immunodeficiency virus (HIV)/acquired immune deficiency syndro
Memórias do Instituto Oswaldo Cruz. Publicado em: 2012-06
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5. Resistência Primária aos Antirretrovirais e Mapeamento Genético do HIV-1 no Estado do Mato Grosso / Primary Antiretroviral Resistance and High HIV-1 Genetic Diversity in Patients from Mato Grosso State, Central West Brazil
O uso de antirretrovirais (ARVs) reduziu a morbi-mortalidade relacionada à infecção pelo vírus da imunodeficiência humana (HIV). Apesar deste avanço, as mutações de resistência aos antirretrovirais e a diversidade genética do HIV-1 permanecem os principais obstáculos na luta contra a AIDS. O padrão de resistência do HIV-1 aos ARVs pode ser deter
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/03/2011
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6. Resistência primária aos antirretrovirais e diversidade genética do HIV-1 em pacientes do estado do Tocantins. / HIV-1 Primary Antiretroviral Resistance and Genetic Diversity in Patientsn Of Tocantins State, Brazil
Diferenças regionais na epidemiologia molecular do HIV-1 têm sido descritas no Brasil e publicações sobre a epidemia da região Norte do país são restritas. Apesar do grande número de drogas antirretrovirais (ARV) das classes inibidores nucleosídicos e não-nucleosídicos (INTR e INNTR) da transcriptase reversa e inibidores da protease (IP), mutaçõ
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/02/2011
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7. Resistência primária aos antirretrovirais e diversidade genética do HIV-1 em pacientes do estado do Tocantins. / HIV-1 Primary Antiretroviral Resistance and Genetic Diversity in Patientsn Of Tocantins State, Brazil
Diferenças regionais na epidemiologia molecular do HIV-1 têm sido descritas no Brasil e publicações sobre a epidemia da região Norte do país são restritas. Apesar do grande número de drogas antirretrovirais (ARV) das classes inibidores nucleosídicos e não-nucleosídicos (INTR e INNTR) da transcriptase reversa e inibidores da protease (IP), mutaçõ
Publicado em: 2011
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8. Genetic analysis of protease and reverse transcriptase of HIV-1 from Southern Brazil naïve clinical isolates
Background: Rio Grande do Sul, the southernmost state of Brazil, presents an atypical epidemiological situation where HIV-1 subtype C co-circulates with subtypes B and CRF31_BC, contrasting with the other Brazilian regions were subtypes B and F dominates. These infections have been effectively managed with highly active antiretroviral therapy (HAART) since 1
Publicado em: 2010
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9. Prevalence of antiretroviral drug resistance among treatment-naive and treated HIV-infected patients in Venezuela
An in-house, low-cost method was developed to determine the genotypic resistance of immunodeficiency virus type 1 (HIV-1) isolates. All 179 Venezuelan isolates analysed belonged to subtype B. Primary drug resistance mutations were found in 11% of 63 treatment-naïve patients. The prevalence of resistance in isolates from 116 HIV-positive patients under antir
Memórias do Instituto Oswaldo Cruz. Publicado em: 2009-05
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10. Resistencia aos farmacos antimicobacterianos em um hospital terciario : utilidade do metodo de microdiluição em placa com sal de tetrazolium / Susceptibility of M. Tuberculosis to first-line antimycobacterial agents in Brazilian hospital : asessing the utility of the tetrazolium (MTT) microplate assay
This cross-sectional, hospital-based study conducted between January 2006 and March 2008 sought to estimate the resistance of M. tuberculosis to first-line drugs among patients with tuberculosis confirmed by culture at a Brazilian hospital and evaluate the performance of the [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide] (MTT) microplate ass
Publicado em: 2009
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11. Fatores clínicos e sociais relacionados com o tempo de hospitalização de pacientes com tuberculose na enfermaria de tisiopneumologia do Hospital Eduardo De Menezes, em Belo Horizonte, no ano de 2008
Tuberculosis is an infectious disease that affects millions of people around the world, thus becoming a serious public health problem. Treatment should be done, preferably, on an outpatient basis, as recommended by the DOTS strategy (Directly Observed Treatment). Hospitalization is recommended only in cases of meningoencephalitis, clinical indications and su
Publicado em: 2009
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12. Molecular characterisation of newly identified HIV-1 infections in Curitiba, Brazil: preponderance of clade C among males with recent infections
As in many areas of Brazil, the AIDS epidemic in Curitiba is relatively stable, but surveillance is important to support public policy. The molecular characteristics of HIV may be instrumental for monitoring epidemic trends. We evaluated plasma HIV-1 RNA (n = 37) from 38 cases presenting with positive serology, who were among 820 consenting volunteers visiti
Memórias do Instituto Oswaldo Cruz. Publicado em: 2008-12