Hole Board
Mostrando 1-12 de 23 artigos, teses e dissertações.
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1. Avaliação neurocomportamental e níveis de acetilcolinesterase cerebral em ratos expostos subcronicamente ao fipronil
RESUMO O fipronil é um inseticida de toxicidade seletiva amplamente empregado na agricultura e na medicina veterinária. Porém, há relatos de efeitos neurotóxicos dessa substância, que geram prejuízos para vertebrados. Avaliou-se a atividade locomotora, a coordenação motora e a atividade da enzima acetilcolinesterase cerebral em ratos expostos ao fip
Arq. Bras. Med. Vet. Zootec.. Publicado em: 2020-01
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2. Rats treated with Hypericum perforatum during pregnancy generate offspring with behavioral changes in adulthood
Abstract Drugs used in the treatment of depression can cross the placenta giving rise to questions regarding the effects these drugs exert on the fetus. Hypericum perforatum L., Hypericaceae, is a natural product used to treat depression. However, information about its toxicity and the occurrence of alterations in the central nervous system development of th
Rev. bras. farmacogn.. Publicado em: 2017-06
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3. Evaluation of postpartum behaviour in rats treated with Hypericum perforatum during gestation
Gestational depression is detrimental to the health of the mother and the offspring and contributes to the appearance of depressive and anxiety symptoms during the postnatal period. Traditional antidepressants have undesirable side effects when utilised during gestation, but Hypericum perforatum has been characterised as an efficient and safe antidepressant
Rev. bras. farmacogn.. Publicado em: 2013-10
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4. Anxiolytic and sedative properties of hydroethanolic extract of Telfairia occidentalis leaves in mice
Telfairia occidentalis Hook. f., Cucurbitaceae, is a leafy vegetable used in soup and folk medicine in southern Nigeria. This study was conducted to investigate the anxiolytic and sedative activities of the hydroethanolic extract of the leaves of T. occidentalis in mice. The hole-board, elevated plus maze, open-field, light-dark, and social interaction tests
Rev. bras. farmacogn.. Publicado em: 22/11/2012
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5. Anxiolytic-like and sedative effects of Kyllinga brevifolia in mice
Kyllinga brevifolia Rottb., Cyperaceae, rhizomes have been widely used in the Paraguayan folk medicine as digestive, diuretic, sedative, tonic, antispasmodic and sudorific. The purpose of this study is to characterize the putative sedative, anxiolytic effects of the crude hydro-ethanolic extract (CEKb) and fractions of the rhizome of K. brevifolia, in male m
Rev. bras. farmacogn.. Publicado em: 20/09/2012
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6. Avaliação da atividade tipo ansiolítica do óleo essencial das folhas de Spiranthera odoratissima A. St. Hil. - possível mecanismo envolvido / Anxiolytic-like activity of essential oil from Spiranthera odoratissima A. St. Hil. leaves possible mechanism evolved
Anxiety is among the most common chronic disease in the world. In Brasília city (capital of Brazil), anxiety disorders affect 12.1 % of population and are the most prevalent psychiatry disease. Since the introduction of benzodiazepines in the 1960s, they have been the most commonly prescribed treatment for anxiety disorders. However, their side-effects such
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2011
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7. Differential behavioral outcomes of 3,4-methylenedioxymethamphetamine (MDMA-ecstasy) in anxiety-like responses in mice
Anxiolytic and anxiogenic-like behavioral outcomes have been reported for methylenedioxymethamphetamine (MDMA or ecstasy) in rodents. In the present experiment, we attempted to identify behavioral, hormonal and neurochemical outcomes of MDMA treatment to clarify its effects on anxiety-related responses in 2-month-old Balb/c male mice (25-35 g; N = 7-10 mice/
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-05
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8. Chronic consumption of distilled sugarcane spirit induces anxiolytic-like effects in mice
OBJECTIVE: Chronic ethanol consumption is a major public health problem throughout the world. We investigated the anxiolytic-like effects and the possible ever injury induced by the chronic consumption of ethanol or sugarcane spirit in mice. METHOD: Adult mice were exposed to a two-bottle free-choice paradigm for 6 weeks. The mice in Group A (n = 16) had acc
Clinics. Publicado em: 2011
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9. Interference of propylene glycol with the hole-board test
Experimental drugs and/or plant extracts are often dissolved in solvents, including propylene glycol. Nevertheless, there is evidence for psychoactive properties of this alcohol. In this study we found that in the hole-board test 10% propylene glycol did not modify the headdipping behavior. However, 30% propylene glycol induced an increase in the number of h
Publicado em: 2010
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10. Aspectos neuroimunológicos do ecstasy (N-metil-3,4-Metilenodioximetanfetamina-MDMA), na inflamação alérgica pulmonar em camundongos Balb/C. / Neuroimmunological aspects of ecstasy (N-methyl-3,4-Methylenedioxymethamphetamine-MDMA) on lung inflammatory response in Balb/C mice.
O N-metil- 3-4, metilenodioximetanfetamina (MDMA) ou ecstasy tem sido freqüentemente usado por jovens. Analisamos neste trabalho, dentro de uma perspectiva neuroimune, os efeitos da administração aguda de MDMA em parâmetros comportamentais, neuroendócrinos, hematatológicos e imunes de camundongos Balb/C, usando para esta última finalidade um modelo de
Publicado em: 2010
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11. InvestigaÃÃo dos efeitos centrais e gastroprotetores do isopulegol em camundongos / Evaluation of the central nervous system and gastroprotective effects of isopulegol in mice.
Isopulegol is a monoterpene alcohol present in the essential oils of various plants, and has been used in the manufacture of fragrances with blossom compositions. In order to investigate its effects on animal models of CNS actions, isopulegol was administered to male Swiss mice at single doses of 25 and 50 mg/kg 30 (i.p.) or 60 min (p.o.) before the experime
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/08/2009
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12. Avaliação do efeito ansiolítico de Rauvolfia ligustrina Willd: ex Roem. & Schult., Apocynaceae, nos testes do labirinto em cruz elevado e placa-perfurada
Rauvolfia ligustrina Willd. ex Roem. & Schult. (Apocynaceae) é conhecida popularmente como "arrebenta-boi" e "paratudo". Em triagem farmacológica comportamental o extrato etanólico das raízes de R. ligustrina (EER) mostrou efeito depressor do SNC e propriedades anticonvulsivantes. O presente estudo buscou avaliar o possível efeito ansiolítico do EER ut
Revista Brasileira de Farmacognosia. Publicado em: 2009-12