Hsc70
Mostrando 1-12 de 164 artigos, teses e dissertações.
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1. Inhibition of rotavirus ECwt infection in ICR suckling mice by N-acetylcysteine, peroxisome proliferator-activated receptor gamma agonists and cyclooxygenase-2 inhibitors
Live attenuated vaccines have recently been introduced for preventing rotavirus disease in children. However, alternative strategies for prevention and treatment of rotavirus infection are needed mainly in developing countries where low vaccine coverage occurs. In the present work, N-acetylcysteine (NAC), ascorbic acid (AA), some nonsteroidal anti-inflammato
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-09
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2. Different levels of hsp70 and hsc70 mRNA expression in Iberian fish exposed to distinct river conditions
Comprehension of the mechanisms by which ectotherms, such as fish, respond to thermal stress is paramount for understanding the threats that environmental changes may pose to wild populations. Heat shock proteins are molecular chaperones with an important role in several stress conditions such as high temperatures. In the Iberian Peninsula, particularly in P
Genet. Mol. Biol.. Publicado em: 2013
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3. Hipersensibilidade do seio carotídeo: prevalência em pacientes com síncope e pré-síncope e comparação com indivíduos assintomáticos / Carotid sinus hypersensitivity: prevalence in patients with syncope and near syncope and comparison with asymptomatic individuals
INTRODUÇÃO: A Hipersensibilidade do seio carotídeo (HSC) é a exacerbação do reflexo normal e foi definida como ocorrência de pausa ventricular 3 segundos ou redução da pressão arterial sistólica (PAS) 50 mmHg em resposta à massagem do seio carotídeo (MSC). Fenômeno relacionado à idade, raramente diagnosticado em pacientes com menos de 50 anos,
Publicado em: 2011
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4. Análise proteômica das respostas agudas e crônicas ao exercício de endurance no músculo esquelético de ratos / Proteomic investigation of the acute and chronic changes in rat skeletal muscle in reseponse to endurence exercise
In the present work the acute and chronic changes in rat skeletal muscle in response to endurance exercise were investigated by proteomic analysis. The results are presented in two separated studies. In the first study gastrocnemius muscle were sampled from control non exercised animals and from animals exercised to exhaustion in an incremental manner in a t
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/04/2010
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5. Identificação de proteínas que interagem com a porção citoplasmática C-terminal do receptor para Angiotensina II (AT1aR) em células de tecido renal / Identification of binding-partners interacting with the intracellular c-terminal domain of the angiotensin II receptor AT1aR in rat renal tissue
O receptor para Angiotensina II tipo 1 (AT1R) é expresso tanto em membrana apical quanto basolateral dos túbulos proximais renais. Embora haja evidências de diferenças funcionais entre receptores apicais e basolaterais, como, por exemplo, a dependência do processo de internalização de receptores apicais, mas não de basolaterais, para a efetivação d
Publicado em: 2010
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6. Gentamicin-induced preconditioning of proximal tubular LLC-PK1 cells stimulates nitric oxide production but not the synthesis of heat shock protein
Nephrotoxicity is the main side effect of antibiotics such as gentamicin. Preconditioning has been reported to protect against injuries as ischemia/reperfusion. The objective of the present study was to determine the effect of preconditioning with gentamicin on LLC-PK1 cells. Preconditioning was induced in LLC-PK1 cells by 24-h exposure to 2.0 mM gentamicin
Brazilian Journal of Medical and Biological Research. Publicado em: 22/05/2009
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7. Sistemas neuromodulatórios: implicações fisiopatológicas / Neuromodulatory systems: patophysiologic implications
Adenosine has been shown to modulate cardiovascular control at the levels of the nucleus tractus solitarii (NTS). This study shows the distribution and density of adenosine A1 receptor within the nucleus tractus solitarii (NTS) of Wistar Kyoto (WKY) and spontaneously hypertensive (SHR) rats from birth to adulthood (1,15,30 and 90 day-old). [3H]DPCPX was used
Publicado em: 2008
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8. Identification and in silico analysis of the Citrus HSP70 molecular chaperone gene family
The completion of the genome sequencing of the Arabidopsis thaliana model system provided a powerful molecular tool for comparative analysis of gene families present in the genome of economically relevant plant species. In this investigation, we used the sequences of the Arabidopsis Hsp70 gene family to identify and annotate the Citrus Hsp70 genes represente
Genetics and Molecular Biology. Publicado em: 2007
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9. Identification of the divergent calmodulin binding motif in yeast Ssb1/Hsp75 protein and in other HSP70 family members
Yeast soluble proteins were fractionated by calmodulin-agarose affinity chromatography and the Ca2+/calmodulin-binding proteins were analyzed by SDS-PAGE. One prominent protein of 66 kDa was excised from the gel, digested with trypsin and the masses of the resultant fragments were determined by MALDI/MS. Twenty-one of 38 monoisotopic peptide masses obtained
Brazilian Journal of Medical and Biological Research. Publicado em: 22/09/2006
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10. Identificação, caracterização e estudo da expressão dos genes hsc70 e hsp83 em Rhynchosciara americana / Identification, characterization and study of expression of the genes hsc70 and hsp83 in Rhynchosciara americana
With the idea of identify some of these proteins involved in the folding process of the proteins synthesized on the Rhynchosciara salivary gland, this project started adopting the shotgun cDNA sequencing strategy. This cDNA library was constructed utilizing salivary glands of Rhynchosciara americana at a developmental period where the cocoon construction beg
Publicado em: 2005
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11. Uso de técnicas de proteoma e genoma funcional para revelar as bases moleculares da ação anti-tumoral de ácido retinóico / Use of proteomics and functional genomics to unravel the molecular mechanisms of retinoic acid as an anti-tumor agent
Controlar a proliferação celular de tumores é um objetivo que vem sendo perseguido há décadas, com moderado sucesso na maioria dos casos. Dentre os diversos tipos de tumores que atingem a humanidade, alguns gliomas são considerados os mais fatais, por haver pouca ou nenhuma alternativa de tratamento efetivo. Agentes que apresentam propriedades anti-tum
Publicado em: 2005
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12. Role of heat shock cognate 70 protein in import of ornithine transcarbamylase precursor into mammalian mitochondria.
The roles of the 70-kDa cytosolic heat shock protein (hsp70) in import of precursor proteins into the mitochondria were postulated to be related to (i) unfolding of precursor proteins in the cytosol, (ii) maintenance of the import-competent state, and (iii) unfolding and transport of precursor proteins through contact sites, in cooperation with matrix hsp70.