Hydrazine
Mostrando 1-12 de 162 artigos, teses e dissertações.
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1. Cuprous oxide nanoparticles: preparation and evaluation of antifouling activity
There are few methods to obtain uniform and well dispersed cuprous oxide nanoparticles, which limits its application widely. In this research, an improved method to prepare nanoparticles was introduced. Cuprous oxides were prepared by the reduction of cupric nitrate, with hydrazine hydrate as a reductant in the presence of glucose. The nanoparticles formed h
Quím. Nova. Publicado em: 15/08/2019
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2. Assessment of anti-diabetic activity of a novel hydrazine-thiazole derivative: in vitro and in vivo method
Diabetes mellitus is a chronic disease resulting in oxidative stress that promotes tissue damage. The appearance of this disease is highly related to lifestyle and food of the population, being of great interest to search for a dietary supplement that can also act by reducing oxidative alterations. Based on the broad range of biological activity of thiazole
Braz. J. Pharm. Sci.. Publicado em: 10/07/2019
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3. Streamlined Synthesis of 6-((1H-1,2,3-Triazol-4-yl)methyl)-1H-pyrrolo [3,4-d]pyridazin-1-one System via Sequential N-Alkylation, CuAAC, and [4 + 2] Cyclization Reactions
An efficient sequential three-step reaction methodology for the synthesis of three new series-1-(prop-2-yn-1-yl)-1H-pyrroles, methyl 4-acetyl-1-((1H-1,2,3-triazol-4-yl)methyl)-1H-pyrrole-3-carboxylates and 6-((1H-1,2,3-triazol-4-yl)methyl)-2,6-dihydro-1H-pyrrolo[3,4-d]pyridazin-1-ones-is reported. The methodology comprises: (i) N-alkylation reactions of poly
J. Braz. Chem. Soc.. Publicado em: 23/05/2019
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4. Synthesis of some novel pyrimidine, thiophene, coumarin, pyridine and pyrrole derivatives and their biological evaluation as analgesic, antipyretic and anti-inflammatory agents
Pyrimidine derivative 3 was afforded through the reaction of compound (1) with 5-ureidohydantion (2). Product 3 underwent a cyclization to produce fused pyrimidine derivative 7, although the latter product 7 was synthesized through one step via the reaction of compound (1) with 5-ureidohydantion (2) using another catalyst. Compound 3 was oriented to react wi
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
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5. Synthesis of New trans-Dehydrocrotonin Nitrogenated Derivatives and their Cytotoxic and DNA-Topoisomerase I Inhibitory Activities
A new series of 19-nor-clerodane diterpene derivatives was synthesized from the natural trans-dehydrocrotonin obtained from stem barks of Croton cajucara (Euphorbiaceae), a native medicinal plant of the Brazilian Amazon. The new derivatives were obtained by changes in the ketone moiety of trans-dehydrocrotonin leading to nitrogenated derivatives which are: t
J. Braz. Chem. Soc.. Publicado em: 2018-01
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6. NEW SEMISYNTHETIC DERIVATIVES OF A BENZYLISOTHIOCYANATE ISOLATED FROM Moringa oleifera AND EVALUATION OF THEIR CYTOTOXIC ACTIVITY
From the natural product 4-(4'-O-acetyl-α-L-rhamnosyloxy)benzylisothiocyanate (1), isolated from the flowers of Moringa oleifera Lam (Moringaceae), four new semisynthetic derivatives, N-[4-(4'-O-acetyl-α-L-rhamnosyloxy)benzyl]-2-(pyridinil-4-carbonil)hydrazine-1-carbothioamide (3), 4-(4'-O-acetyl-2',3'-dimesyloxy-α-L-rhamnosyloxy)benzylisothiocyanate (4),
Quím. Nova. Publicado em: 2017-10
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7. Catechol Oxidase, Phosphatase-Like Activity, DNA/BSA Binding Studies of RuII Complexes of S-Allyldithiocarbazate: Synthesis and Spectral Studies
New ruthenium(II) complexes with formulae [RuCl(CO)(PPh3)2L1] and [RuCl(CO)(PPh3)2L2] (L1 = S-allyl-4-methoxy benzylidene hydrazine carbodithioate, L2 = S-allyl-1-naphthylidene hydrazine carbodithioate) have been synthesized and characterized by elemental analysis, Fourier transform infrared (FTIR), nuclear magnetic resonance (NMR), UV-Vis, electrospray ioni
J. Braz. Chem. Soc.. Publicado em: 2017-08
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8. The Role that Electrolytes Play in the Synthesis of Water-Soluble CdTe Quantum Dots Prepared at Ambient Temperature
In this work, we have synthesized CdTe quantum dots (QDs) dispersed in an aqueous medium at ambient temperature, and investigated their optical properties. Synthesis of CdTe QDs in the presence of simple amines removed the need for an additional energy source and inert atmosphere, in a simple and inexpensive experimental setup. The use of ammonia or hydrazin
J. Braz. Chem. Soc.. Publicado em: 2017-07
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9. Synthesis and Characterization of a New Unsymmetrical Potentially Pentadentate Schiff Base Ligand and Related Complexes with Manganese(II), Nickel(II), Copper(II), Zinc(II) and Cadmium(II)
New unsymmetric thioether Schiff base amine, 2-(2-aminoethylthio)-N-(thiophene-2-ylmethylene)aniline was prepared by reaction of 2-aminothiophenol with N-(2-bromoethyl)phthalimide and then by thiophene-2-carbaldehyde. Then, the phthalimide group converted to the amine by hydrazine hydrate. The new potentially pentadentate N3S2 donor unsymmetrical Schiff base
J. Braz. Chem. Soc.. Publicado em: 2017-05
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10. Strategies for Molecular Diversification of 2-[Aminoalkyl-(1H-1,2,3-triazol-1- yl)]-1,4-naphthoquinones Using Click Chemistry
Click chemistry-based strategies for the synthesis of 2-amino-alkyl-1,2,3-triazole-1,4-naphthoquinone derivatives make it possible to obtain desired products from 1,4-naphthoquinone (1,4-NQ), and bio-based lawsone, nor-lapachol and lapachol. The first route (Strategy A) starting from 1,4-NQ and amino alcohols, then 2-amino-alkyl-1,4-NQ alcohols, were tosylat
J. Braz. Chem. Soc.. Publicado em: 2017-04
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11. NANOBIOCATALYTIC SYSTEMS BASED ON LIPASE-Fe3O4 AND CONVENTIONAL SYSTEMS FOR ISONIAZID SYNTHESIS: A COMPARATIVE STUDY
Abstract Superparamagnetic nanomaterials have attracted interest in many areas due to the high saturation magnetization and surface area. For enzyme immobilization, these properties favor the enzyme-support contact during the immobilization reaction and easy separation from the reaction mixture by use of low-cost magnetic processes. Iron oxide magnetic nanop
Braz. J. Chem. Eng.. Publicado em: 2016-09
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12. Synthesis, spectral analysis and pharmacological study of N'- substituted-2-(5-((2,4-dimethylphenoxy)methyl)-1,3,4-oxadiazol-2-ylthio)acetohydrazides
ABSTRACT A series of molecules bearing multiple functional groups were synthesized to study their antibiotic effect against Gram-positive and Gram-negative bacteria and lipoxygenase activity as well. 2,4-Dimethylcarbolic acid (1) was refluxed with ethyl 2-bromoacetate to synthesize ethyl 2-(2,4-dimethylphenoxy)acetate (2). Compound 2 was converted to the cor
Braz. J. Pharm. Sci.. Publicado em: 2016-09