Hydrophobic Parameter
Mostrando 1-12 de 32 artigos, teses e dissertações.
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1. Lipophilicity Study of Thiazolo[3,2-a]pyrimidine Derivatives as Potential Bioactive Agents
Systems containing fused thiazole and pyrimidine rings play a significant role in organisms due to their biological activity. Lipophilicity, as important parameter to expect biological activity of the compounds, was evaluated for 27 potentially active thiazolo[3,2-a]pyrimidine derivatives using chromatographic methods: reversed phase thin layer chromatograph
J. Braz. Chem. Soc.. Publicado em: 2016-09
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2. Comparison of adsorption equilibrium and kinetic models for a case study of pharmaceutical active ingredient adsorption from fermentation broths: parameter determination, simulation, sensitivity analysis and optimization
Mathematical models for a batch process were developed to predict concentration distributions for an active ingredient (vancomycin) adsorption on a representative hydrophobic-molecule adsorbent, using differently diluted crude fermentation broth with cells as the feedstock. The kinetic parameters were estimated using the maximization of the coefficient of de
Braz. J. Chem. Eng.. Publicado em: 2012-09
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3. Classification of polymers insulators hydrophobicity basead on digital image processing
Although the hydrophobicity is usually an arduous parameter to be determined in the field, it has been pointed out as a good option to monitor aging of polymeric outdoor insulators. Concerning this purpose, digital image processing of photos taken from wet insulators has been the main technique nowadays. However, important challenges on this technique still
Materials Research. Publicado em: 27/03/2012
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4. Biological sensors based on immune response cells applied to the study of anti-allergic activity of natural compounds. / Utilização de sensores biológicos baseados em células de resposta imune no estudo da atividade antialérgica de substâncias naturais.
Anti-allergic activity of extracts and isolated compounds obtained from natural sources was investigated using the mast-cell based biosensor system. Mast cells release beta-hexosaminidase enzyme which is used as a marker of degranulation. Flavonoids (quercetin-Qc and rutin-Rt) and polyphenolic acids (caffeic acid-Cf and dimethoxy cinnamic acid-Dm) were used
Publicado em: 2009
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5. Estudos de sistemas micelares usando voltametria com microeletrodos / Studies of micellar systems with microelectrode voltammetry
Voltammetry with platinum disc microelectrodes was employed to gain information on diffusion coefficients, D, of micelles in aqueous solution. Owing to the low solubility in water and high affinity for the micellar core, ferrocene was used as electroactive probe. Diffusion coefficients of hexadecyl trimethyl ammonium bromide (C16TABr) were determined in solu
Publicado em: 2008
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6. Desenvolvimento de processos de deposição de filmes filmes sobre substratos polimericos fotopolimerizdos / Development of process of deposition of thin films on photopolymerization polymeric substrats
A new era has begun all around the world. The quality of life and health depends more and more on the human capacity of resolving problems that are becoming longer and more complex day by day. As communication and globalization advance, time becomes scarcer and more precious. The semiconductor materials which are used to activate the logical functions, the h
Publicado em: 2007
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7. The powerful high pressure tool for protein conformational studies
The pressure behavior of proteins may be summarized as a the pressure-induced disordering of their structures. This thermodynamic parameter has effects on proteins that are similar but not identical to those induced by temperature, the other thermodynamic parameter. Of particular importance are the intermolecular interactions that follow partial protein unfo
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-08
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8. Comparative study of the hydrophobic and ionization parameters of a series of procaine derivatives with neuromuscular blocking activity / Estudo comparativo de parâmetros hipidrofóbicos e, relacionados à ionização, de série de derivados da procaína com atividade bloqueadora neuromuscular
O estudo das Relações Quantitativas entre Estrutura química e Atividade biológica (QSAR/QSAR-3D) utilizando diferentes estratégias metodológicas complementares, aplicadas iterativamente, se estende a diferentes áreas de aplicação. Dentre elas destaca-se o planejamento racional de novos fármacos e o estudo de seus mecanismos de ação. Moléculas ca
Publicado em: 2003
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9. Aplicações de técnicas espectroscópicas e polarográficas para caracterização e avaliação da reatividade do húmus com o herbicida atrazina. / Application of spectroscopic and polarographic methods to characterize and evaluate the reactivity between humus and atrazine.
One alternative to disposal of urban residues is recycling through composts and earthworm composts (humus production). The absence of a quality standard of these materials however brings limitations to commercial development with damage to producers and consumers. In this work was proposed a strategic parameter to be used as standard. From Electron Paramagne
Publicado em: 1999
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10. Role of Positional Hydrophobicity in the Leishmanicidal Activity of Magainin 2
The emergence of membrane-active antimicrobial peptides as new alternatives against pathogens with multiantibiotic resistance requires the design of better analogues. Among the different physicochemical parameters involved in the optimization of linear antimicrobial peptides, positional hydrophobicity has recently been incorporated. This takes into considera
American Society for Microbiology.
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11. Susceptibility to hydrophobic molecules and phospholipid composition in Pasteurella multocida and Actinobacillus lignieresii.
Despite its typically gram-negative cell envelope ultrastructure, Pasteurella multocida is susceptible to the hydrophobic antibiotic novobiocin and is unable to initiate growth on MacConkey agar, a parameter often used to effect is differentiation from other members of the family Pasteurellaceae such as Actinobacillus lignieresii. However, growth on basal me
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12. Variability of cell surface hydrophobicity among Pasteurella multocida somatic serotype and Actinobacillus lignieresii strains.
Pasteurella multocida possesses a characteristically gram-negative ultrastructure, yet its inability to grow in the presence of hydrophobic compounds and the general penicillin susceptibility of genera making up the family Pasteurellaceae suggest a cell envelope having atypical permeability properties. The cell surface hydrophobicity properties of strains re