Hypercholesteremia
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Comparative study on effects of rosuvastatin and atrovastatin in plasmatic lipidids, lipidic peroxidation, tissuel cholesterol and endothelium disfunction in hypercholesterolemic rabbits / Estudo comparativo dos efeitos da rosuvastatina e atorvastatina nos lipides plasmaticos, peroxidação lipidica e função endotelial em coelhos hipercolesterolemicos
Objective: The aim of this study was to detect the effect of the rosuvastatin on plasmatic lipids, lipidic peroxidation, tis sueI cholesterol, and endothelium disfunction and to compare its effect with the atorvastatin in hypercholesterolemic rabbits. Methods: Forty male New Zealand white rabbits were randomized in Four Groups: Group Hypercholesterolemic (GH
Publicado em: 2007
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2. THE ROLE OF EXOGENOUS LIPIDS IN THE HYPERLIPEMIA AND HYPERCHOLESTEREMIA OF NEPHROTIC RATS 1
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3. THE CAUSAL ROLE OF PLASMA ALBUMIN DEFICIENCY IN EXPERIMENTAL NEPHROTIC HYPERLIPEMIA AND HYPERCHOLESTEREMIA 1
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4. Inhibition of host resistance by nutritional hypercholesteremia.
Previous experiments showed that nutritionally induced hypercholesteremia in mice caused an increase in susceptibility to coxsackievirus B, with a marked suppression of cellular infiltrates in infected tissues and an increased mortality. The present studies demonstrated that a hypercholesteremic diet was associated with an inhibition in host resistance as me
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5. AN EVALUATION OF POTASSIUM IODIDE AS A THERAPEUTIC AGENT IN THE TREATMENT OF EXPERIMENTAL HYPER-CHOLESTEREMIA AND ATHEROSCLEROSIS 1
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6. Mutation scanning by meltMADGE: Validations using BRCA1 and LDLR, and demonstration of the potential to identify severe, moderate, silent, rare, and paucimorphic mutations in the general population
We have developed a mutation-scanning approach suitable for whole population screening for unknown mutations. The method, meltMADGE, combines thermal ramp electrophoresis with MADGE to achieve suitable cost efficiency and throughput. The sensitivity was tested in blind trials using 54 amplicons representing the BRCA1 coding region and a panel of 94 unrelated
Cold Spring Harbor Laboratory Press.
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7. Suppression of experimental atherosclerosis by the Ca++-antagonist lanthanum. Possible role of calcium in atherogenesis.
Agents inhibiting calcium deposition into arteries are known to suppress atherosclerosis in animals. However, the precise role of calcium in atherogenesis is unknown. In this study, the specific Ca2+-antagonist lanthanum was used to attempt suppression of experimental atherosclerosis and to gain more insight into the possible effects of calcium on atherogene
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8. Cell cycle-specific effects of lovastatin.
Lovastatin (LOV), the drug recently introduced to treat hypercholesteremia, inhibits the synthesis of mevalonic acid. The effects of LOV on the cell cycle progression of the human bladder carcinoma T24 cell line expressing activated p21ras were investigated. At a concentration of 2-10 microM, LOV arrested cells in G1 and also prolonged--or arrested a minor f