Hypertonic Saline
Mostrando 1-12 de 139 artigos, teses e dissertações.
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1. Hypertonic saline and pentoxifylline enhance survival, reducing apoptosis and oxidative stress in a rat model of strangulated closed loop small bowel obstruction
OBJECTIVES: Intestinal obstruction has a high mortality rate when therapeutic treatment is delayed. Resuscitation in intestinal obstruction requires a large volume of fluid, and fluid combinations have been studied. Therefore, we evaluated the effects of hypertonic saline solution (HS) with pentoxifylline (PTX) on apoptosis, oxidative stress and survival ra
Clinics. Publicado em: 06/06/2019
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2. Perconditioning associated to hypertonic saline solution on liver function improvement after ischemia/reperfusion injury
Abstract Purpose: To evaluate the effects of hypertonic saline solution associated to remote ischemic perconditioning in liver ischemia/reperfusion injury in rats. Methods: 25 male rats (Wistar) were distributed into five groups: Sham group (S); Ischemia/Reperfusion group (I/R) with 30 minutes of liver ischemia; Remote ischemic perconditioning group (Per)
Acta Cir. Bras.. Publicado em: 2017-11
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3. Effects of hypertonic saline solution associated to remote ischemic perconditioning in kidney ischemia/reperfusion injury in rats
Abstract Purpose: To evaluate the effects of hypertonic saline solution associated to remote ischemic perconditioning in renal ischemia/reperfusion injury in rats. Methods: Twenty five male rats (Wistar) underwent right nephrectomy and were distributed into five groups: Sham group (S); Ischemia/Reperfusion group (I/R) with 30 minutes of renal ischemia; Rem
Acta Cir. Bras.. Publicado em: 2017-03
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4. Cardiovascular Effects of Shock and Trauma in Experimental Models. A Review
Abstract Experimental models of human pathology are useful guides to new approaches towards improving clinical and surgical treatments. A systematic search through PubMed using the syntax (shock) AND (trauma) AND (animal model) AND (cardiovascular) AND ("2010/01/01"[PDat]: "2015/12/31"[PDat]) found 88 articles, which were reduced by manual inspection to 43 e
Braz. J. Cardiovasc. Surg.. Publicado em: 2016-02
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5. Effect of hypertonic saline treatment on the inflammatory response after hydrochloric acid-induced lung injury in pigs
OBJECTIVES:Hypertonic saline has been proposed to modulate the inflammatory cascade in certain experimental conditions, including pulmonary inflammation caused by inhaled gastric contents. The present study aimed to assess the potential anti-inflammatory effects of administering a single intravenous dose of 7.5% hypertonic saline in an experimental model of
Clinics. Publicado em: 2015-08
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6. Mannitol versus hypertonic saline for brain relaxation in patients undergoing craniotomy
BACKGROUND: Patients with brain tumour usually suffer from increased pressure in the skull due to swelling of brain tissue. A swollen brain renders surgical removal of the brain tumour difficult. To ease surgical tumour removal, measures are taken to reduce brain swelling, often referred to as brain relaxation. Brain relaxation can be achieved with intraven
Sao Paulo Med. J.. Publicado em: 2015-04
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7. Pentoxifylline associated to hypertonic saline solution attenuates inflammatory process and apoptosis after intestinal ischemia/reperfusion in rats
PURPOSE: To evaluate intestinal inflammatory and apoptotic processes after intestinal ischemia/reperfusion injury, modulated by pentoxifylline and hypertonic saline.METHODS:It was allocated into four groups (n=6), 24 male Wistar rats (200 to 250g) and submitted to intestinal ischemia for 40 min and reperfusion for 80 min: IR (did not receive any treatment);
Acta Cir. Bras.. Publicado em: 2014-11
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8. Therapeutic effects of compound hypertonic saline on rats with sepsis
Sepsis is one of the major causes of death and is the biggest obstacle preventing improvement of the success rate in curing critical illnesses. Currently, isotonic solutions are used in fluid resuscitation technique. Several studies have shown that hypertonic saline applied in hemorrhagic shock can rapidly increase the plasma osmotic pressure, facilitate the
Braz J Infect Dis. Publicado em: 2014-09
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9. Hypertonic saline for treatment of shock: have we looked for everything?
RESUMO O procedimento de ressuscitação hipertônica a pequeno volume foi originalmente baseado no conceito de que uma expansão fisiologicamente significativa de volume sanguíneo resulta da administração de um pequeno volume de fluido hipertônico. A hipertonia é reconhecidamente um vasodilatador fisioló gico, de modo que seu uso após uma importante
MedicalExpress (São Paulo, online). Publicado em: 2014-02
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10. Safety and efficacy of hypertonic saline versus isotonic saline solution in off-pump coronary artery bypass grafting
RESUMO OBJETIVO: A frequência de revascularização do miocárdio sem circulação extracorpórea aumenta continuamente. No entanto eventos transitórios de baixo débito cardíaco podem ocorrer durante este procedimento; requerem reposição de volume agressiva, o que pode levar a hipervolemia e suas complicações. MÉTODOS: Este estudo avalia a eficác
MedicalExpress (São Paulo, online). Publicado em: 2014-02
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11. ROC trials update on prehospital hypertonic saline resuscitation in the aftermath of the US-Canadian trials
The objectives of this review are to assess the current state of hypertonic saline as a prehospital resuscitation fluid in hypotensive trauma patients, particularly after the 3 major Resuscitation Outcomes Consortium trauma trials in the US and Canada were halted due to futility. Hemorrhage and traumatic brain injury are the leading causes of death in both m
Clinics. Publicado em: 2013-06
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12. Comparison of 7.2% hypertonic saline - 6% hydroxyethyl starch solution and 6% hydroxyethyl starch solution after the induction of anesthesia in patients undergoing elective neurosurgical procedures
OBJECTIVE: The ideal solution for fluid management during neurosurgical procedures remains controversial. The aim of this study was to compare the effects of a 7.2% hypertonic saline - 6% hydroxyethyl starch (HS-HES) solution and a 6% hydroxyethyl starch (HES) solution on clinical, hemodynamic and laboratory variables during elective neurosurgical procedures
Clinics. Publicado em: 2013