Hypospadias Etiology
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Clinical profile of 93 cases of 46, XY disorders of sexual development in a referral center
ABSTRACT The term DSD refers to disorders that affect the normal process of sexual development causing disagreement between chromosomal, gonadal and phenotypic sex, and this study aimed to describe the clinical profile of a group with DSD 46, XY joined on DSD Clinic of Hospital of Salvador, Bahia Clinics. It was a retrospective study of medical records of su
Int. braz j urol.. Publicado em: 2015-10
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2. Medroxyprogesterone acetate administered during pre-natal period causes hypospadia in male and virilization in female mice / "Acetato de medroxiprogesterona administrado em período pré-natal induz hipospádia em machos e virilização em fêmeas de camundongos"
In vitro fertilization (IVF) has been associated with an increase incidence of hypospadias. IVF protocols require the maternal use of progesterone which may be a factor in causing hypospadias. To test these hypotheses in an animal model, we describe the effects of maternal progesterone exposure on genital development in mice. Medroxyprogesterone acetate (MPA
Publicado em: 2005
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3. Intracellular and nuclear binding of [3H]dihydrotestosterone in cultured genital skin fibroblasts of patients with severe hypospadias.
Androgens stimulate the development and growth of the male external genitalia. Because hypospadias is the most common congenital defect of the male urethra and because in most cases the cause of this malformation is unknown, we examined the hypothesis that the etiology of the severe forms of this disorder, which is frequently associated with other genital an
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4. Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development
Malformations of the external genitalia are among the most common congenital anomalies in humans. The urogenital and anorectal sinuses develop from the embryonic cloaca, and the penis and clitoris develop from the genital tubercle. Within the genital tubercle, the endodermally derived urethral epithelium functions as an organizer and expresses sonic hedgehog
Company of Biologists.