Igfbp
Mostrando 1-12 de 148 artigos, teses e dissertações.
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1. Evaluating TIMP-2 and IGFBP-7 as a predictive tool for kidney injury in ureteropelvic junction obstruction
ABSTRACT A major challenge in the management of ureteropelvic junction obstruction (UPJO) is the selection of patients who would benefit from surgical treatment. Tissue inhibitor metalloproteinase-2 (TIMP-2) and insulin-like growth factor-binding protein 7 (IGFBP7) indicate renal cell stress and are associated with cell cycle arrest. The [TIMP-2] [IGFBP7] ra
International braz j urol. Publicado em: 2022
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2. Laboratory investigations in the diagnosis and follow-up of GH-related disorders
ABSTRACT In addition to auxiological, clinical and metabolic features measurements of growth hormone (GH) and insulin-like growth factor I (IGF-I) complement our tools in diagnosis and follow-up of GH-related disorders. While comparably robust during the pre-analytical phase, measurement and interpretation of concentrations of both hormones can be challengin
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
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3. Lack of association between genetic polymorphisms in IGF1 and IGFBP3 with twin births in a Brazilian population (Cândido Godói, Rio Grande do Sul)
Abstract Insulin-like growth factor (IGF-1) is an important peptide hormone involved in the reproduction and fetal development of mammals, and it is suggested that it may influence the human twinning rate. This study aimed to test such possible association, investigating the genetic polymorphisms IGF1 (CA)n and IGFBP3 rs2854744 in the population from Candido
Genet. Mol. Biol.. Publicado em: 29/11/2018
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4. Padronização da quantificação do fator de crescimento semelhante à insulina I (IGF-I) em plasma bovino por ELISA
RESUMO: Esse estudo teve como objetivo a padronização de um ensaio imunoenzimático competitivo (cELISA) in house para a determinação das concentrações plasmáticas do fator de crescimento semelhante a insulina I (IGF-I) total para a espécie bovina, utilizando o sistema de amplificação biotina-estreptavidina peroxidase. O IGF-I foi extraído das pro
Pesq. Vet. Bras.. Publicado em: 2017-12
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5. Reduction of venous pressure during the resection of liver metastases compromises enteric blood flow: IGFBP-1 as a novel biomarker of intestinal barrier injury
OBJECTIVES: Disruption of the intestinal barrier and bacterial translocation commonly occur when intestinal blood flow is compromised. The aim of this study was to determine whether liver resection induces intestinal damage. METHODS: We investigated intestinal fatty-acid binding protein and insulin-like growth factor binding protein levels in the plasma of
Clinics. Publicado em: 2017-10
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6. FORÇA MUSCULAR, GH E IGF-1 EM IDOSAS SUBMETIDAS AO TREINAMENTO DE FORÇA NO SOLO E NA ÁGUA
RESUMO Introdução: O envelhecimento leva ao declínio de múltiplos sistemas de órgãos associado a alterações hormonais e perda de massa e força muscular. Objetivo: Avaliar os efeitos do treinamento de força no meio terrestre e aquático sobre a força muscular e os níveis séricos basais de GH, IGF-1 e IGFBP3 em mulheres idosas. Métodos: Os indi
Rev Bras Med Esporte. Publicado em: 2017-08
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7. Short hairpin RNA targeting insulin-like growth factor binding protein-3 restores the bioavailability of insulin-like growth factor-1 in diabetic rats
ABSTRACT Purpose To investigate whether intracavernosal injection of short hairpin RNA for IGFBP-3 could improve erectile function in streptozotocin-induced diabetic rats. Materials and methods After 12 weeks of IGFBP-3 short hairpin RNA injection treatment, intracavernous pressure responses to electrical stimulation of cavernous nerves were evaluated. T
Int. braz j urol.. Publicado em: 2016-02
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8. Single Nucleotide Polymorphisms in IGFBP-2 Gene and Their Associations with Body Weight Traits on Jinghai Yellow Chicken
ABSTRACT Insulin-like growth factor binding protein-2 (IGFBP-2) regulates a broad spectrum of biological activities involved in growth, development, and differentiation. This study aimed at comparing polymorphisms in intron2 of the IGFBP-2 gene among four chicken breeds and at analyzing the associations between its genotypes and body weight in Jinghai Yellow
Rev. Bras. Cienc. Avic.. Publicado em: 2015-12
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9. A 20-week program of resistance or concurrent exercise improves symptoms of schizophrenia: results of a blind, randomized controlled trial
Objective: To evaluate the effects of 20 weeks of resistance and concurrent training on psychotic and depressive symptoms, quality of life outcomes, and serum IGF-1, IGFBP-3, and brain-derived neurotrophic factor (BDNF) concentrations in patients with schizophrenia. Methods: In this blind, randomized controlled clinical trial, 34 patients with schizophreni
Rev. Bras. Psiquiatr.. Publicado em: 15/09/2015
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10. Clinical significance of miR-140-5p and miR-193b expression in patients with breast cancer and relationship to IGFBP5
The functional role of IGFBP5 in breast cancer is complicated. Experimental and bioinformatics studies have shown that IGFBP5 is targeted by miR-140-5p and miR-193b, although this has not yet been proven in clinical samples. The aim of this study was to evaluate the expression of miR-140-5p and miR-193b in breast cancer and adjacent normal tissue and assess
Genet. Mol. Biol.. Publicado em: 2015-03
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11. Insulin-like growth factor (IgF)-I, IgF binding protein-3, and prostate cancer: correlation with gleason score
Introduction Non-androgenic growth factors are involved in the growth regulation of prostate cancer (PCa). Objective This is the first Brazilian study to correlate, in a population of patients operated for PCa, PSA, total testosterone, insulin-like growth factor-I (IGF-I) and insulin-like growth factor-binding protein-3 (IGFBP-3) with Gleason score and to c
Int. braz j urol.. Publicado em: 2015-02
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12. PPARγ induces growth inhibition and apoptosis through upregulation of insulin-like growth factor-binding protein-3 in gastric cancer cells
Peroxisome proliferator activator receptor-gamma (PPARγ) is a ligand-activated transcriptional factor involved in the carcinogenesis of various cancers. Insulin-like growth factor-binding protein-3 (IGFBP-3) is a tumor suppressor gene that has anti-apoptotic activity. The purpose of this study was to investigate the anticancer mechanism of PPARγ with respe
Braz J Med Biol Res. Publicado em: 13/01/2015