Immunogenic Proteins
Mostrando 1-12 de 452 artigos, teses e dissertações.
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1. Biological and molecular properties of yellow venom of the Amazonian coral snake Micrurus surinamensis
Abstract INTRODUCTION: The coral snake Micrurus surinamensis, which is widely distributed throughout Amazonia, has a neurotoxic venom. It is important to characterize the biological and molecular properties of this venom in order to develop effective antitoxins. METHODS: Toxins from the venom of M. surinamensis were analyzed by two-dimensional polyacryla
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-06
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2. Recombinant 60-kDa heat shock protein from Paracoccidioides brasiliensis: is it a good antigen for serological diagnosis of paracoccidioidomycosis?
Paracoccidioides brasiliensis and P. lutzii are fungi that cause paracoccidioidomycosis (PCM), the most prevalent systemic mycosis in South America. For serological diagnosis, although 43-kDa glycoprotein (gp43) is regarded as highly specific for PCM, the occurrence of false negative reactions in sera from patients infected with P. lutzii suggests that prepa
Braz J Med Biol Res. Publicado em: 03/04/2017
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3. Lectin activity in mycelial extracts of Fusarium species
ABSTRACT Lectins are non-immunogenic carbohydrate-recognizing proteins that bind to glycoproteins, glycolipids, or polysaccharides with high affinity and exhibit remarkable ability to agglutinate erythrocytes and other cells. In the present study, ten Fusarium species previously not explored for lectins were screened for the presence of lectin activity. Myce
Braz. J. Microbiol.. Publicado em: 2016-09
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4. Insights into the posttranslational structural heterogeneity of thyroglobulin and its role in the development, diagnosis, and management of benign and malignant thyroid diseases
ABSTRACT Thyroglobulin (Tg) is the major glycoprotein produced by the thyroid gland, where it serves as a template for thyroid hormone synthesis and as an intraglandular store of iodine. Measurement of Tg levels in serum is of great practical importance in the follow-up of differentiated thyroid carcinoma (DTC), a setting in which elevated levels after total
Arch. Endocrinol. Metab.. Publicado em: 2016-02
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5. Detection of immunogenic proteins from Anopheles sundaicussalivary glands in the human serum
AbstractINTRODUCTION:The saliva of mosquitoes has an important role in the transmission of several diseases, including malaria, and contains substances with vasomodulating and immunomodulating effects to counteract the host physiological mechanisms and enhance pathogen transmission. As immunomodulatory components, salivary gland proteins can induce the gener
Rev. Soc. Bras. Med. Trop.. Publicado em: 2015-08
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6. Synthesis and evaluation of artificial antigens for astragaloside IV
The objective of this study was to produce artificial antigens for astragaloside IV that could be used to prepare antibodies against astragaloside IV screened in Radix astragali (Astragalus membranaceus (Fisch) Bunge, Fabaceae) and its preparations, using an indirect ELISA. Astragaloside IV was coupled to carrier proteins, bovine serum albumin and ovalbumin
Rev. bras. farmacogn.. Publicado em: 2014-06
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7. Identification of an immunogenic protein of Giardia lamblia using monoclonal antibodies generated from infected mice
The humoral immune response plays an important role in the clearance of Giardia lamblia. However, our knowledge about the specific antigens of G. lamblia that induce a protective immune response is limited. The purpose of this study was to identify and characterise the immunogenic proteins of G. lamblia in a mouse model. We generated monoclonal antibodies (m
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-08
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8. Construção de linhagens atenuadas de Salmonella enterica Enteritidis : avaliação do potencial imunogênico e protetor / Cosntruction of attenuated Salmonella enterica Enteritidis strains : evaluation of its immunogenic and protective potential
Salmonella enterica é uma bactéria Gram-negativa classificada em diferentes sorovariedades que podem causar desde gastroenterites a infecções sistêmicas. A sorovariedade Enteritidis é predominante nos casos de salmonelose em humanos, tendo produtos derivados do frango como principal fonte de infecção. Uma forma de se controlar infecções por Enterit
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 04/06/2012
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9. Clonagem molecular do gene ipaC de Shigella sp e estudo da expressão por Lactococcus lactis / Molecular cloning and expression analysis in Lactococcus lactis of ipaC gene from Shigella sp
Shigellosis is a severe intestinal infection caused by Gram-negative bacteria which belongs to the genus Shigella. It is a pathology with high incidence and it is known that 99% of cases occur in underdevelopment countries. Among these cases, 69% of them affect children under 5 years old. The high incidence of Shigella in underdevelopment countries, is mainl
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/05/2012
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10. General characterization of venom from the Moroccan snakes Macrovipera mauritanica and Cerastes cerastes
Ophidian envenomation accidents constitute a serious public health problem in many countries around the globe. Over 5 million such accident cases occur each year causing more than 100,000 deaths. In Africa, more than 20,000 deaths per year are registered while 400,000 envenomation victims retain severe and permanent functional sequelae. In Morocco, snakebite
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 2012
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11. Caracterização funcional da interação entre as proteínas CTSP-1 e CTCF / Functional characterization of the interaction between the proteins CTSP-1 and CTCF.
Cancer-testis (CT) antigens are immunogenic proteins expressed in gametogenic tissues and in different histological types of tumors, being considered promising candidates for cancer immunotherapy. However, little is known about their role in tumorigenesis. In 2006, we identified CTSP-1 as a novel CT antigen, frequently expressed in different types of tumors.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/12/2011
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12. Desenvolvimento e avaliação imunológica de Nanotubos de Carbono funcionalizados com a proteína de envelope de Dengue virus 3
In terms of epidemiologic impact, Dengue (DENV) infections represent the most important infectious disease in Brazil. Consequently, the development of an efficient vaccine is considered a high priority. Due to this fact, many studies are being developed towards this goal, but no vaccine is currently available to the population. Carbon Nanotubes (CNT) have be
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/02/2011