Immunologic Tolerance
Mostrando 1-12 de 47 artigos, teses e dissertações.
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1. Avaliação de viabilidade, tolerância e segurança da vacina com células dendríticas autológas maduras em pacientes com carcinoma de pulmão não pequenas células avançado = : Assessment of feasibility, safety and tolerance of mature autologous dendritic cells vaccine in patients with advanced non-small cell lung carcinoma / Assessment of feasibility, safety and tolerance of mature autologous dendritic cells vaccine in patients with advanced non-small cell lung carcinoma
Os resultados terapêuticos globais do carcinoma de pulmão não pequenas células em estádio avançado são bem limitados. A imunoterapia com células dendríticas foi desenvolvida como uma nova estratégia para o tratamento de câncer de pulmão. O objetivo deste estudo foi avaliar a viabilidade, segurança e respostas imunológicas em pacientes com carci
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/06/2012
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2. Peptídeos urinários no transplante renal humano: busca de um perfil diferencial na tolerância operacional / Urine peptides in human kidney transplantation: research for a differential profile on operational tolerance
Um grupo especial de indivíduos transplantados renais mantém a função do enxerto estável após a total retirada da terapia imunossupressora, alcançando um estado imunológico chamado de Tolerância operacional. Ainda não há marcadores moleculares e celulares que discriminem a tolerância no transplante humano, e os seus mecanismos estão sendo invest
Publicado em: 2010
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3. Study of the immunologic molecular profile in operational tolerance kidney transplanted individuals / Estudo do perfil imunológico molecular em indivíduos transplantados renais com tolerância operacional
standard immunosuppression, lead us to suggest that these cells may be affected by immunosuppression. Moreover, the higher numbers of CD4+CD25+Foxp3+ T cells observed in TO and BI individuals suggest that these cells may have an important role in the induction/maintenance of these two homeostatic states of minimal, or of no aggression to the graft. Furthermo
Publicado em: 2009
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4. Analysis of the promiscuous gene expression in the thymus of NOD (non obese diabetic) mice during onset of type 1 diabetes mellitus / Análise da expressão gênica promíscua no timo de camundongos NOD (non obese diabetic) durante a emergência do Diabetes melitus tipo 1
Immunologic tolerance is an essential property of the immune system, which controls immune reactions directed against the body self components. The thymus is seen as the main organ involved with the tolerance induction to self antigens, which are expressed by the thymic cells (central tolerance), while the tolerance induction to the diverse other peripheral
Publicado em: 2008
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5. Collagen V- induced nasal tolerance in scleroderma experimental model / Indução de tolerância nasal com colágeno tipo V em modelo experimental de esclerodermia
Objective: Our aim was to verify the skin remodeling and antibody production in experimental model of scleroderma in rabbits, after induction of tolerance by daily nasal administration of human type V collagen (Col V). Methods: Female New Zealand rabbits (N=12) were immunized with 1mg/ml of Col V in complete Freunds adjuvant, followed by more two boosters in
Publicado em: 2007
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6. Effect of dendritic cells on the generation of CD4+CD25+Foxp3+ T cells. / Efeito das células dendríticas na geração de células T CD4+CD25+Foxp3+.
As células dendríticas (DCs) são as principais células apresentadoras de antígeno do sistema imune. No entanto, trabalhos têm demonstrado seu envolvimento na manutenção da tolerância imunológica. As células T CD4+CD25+Foxp3+ possuem a capacidade de suprimir respostas imunes. Neste estudo avaliamos as alterações ocorridas na população de célul
Publicado em: 2007
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7. Effects of chronic and prolonged solar radiation in immunologic system of fishermen from Recife, Brazil / Efeitos da radiação solar crônica e prolongada sobre o sistema imunológico de pescadores do Recife
Introduction: The ultraviolet radiation effects on the human immunological system are highly complex, disturbing some components of immune response. Objective: The objective of this study was to evaluate the clinical, histopathological and immunological effects from solar radiation in male fishermen with more than 10 years of uninterrupted activity. Methods:
Publicado em: 2007
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8. Doença tiroideana auto-imune : expressão de colageno IV e laminina e relação com anti-corpos circulantes antimembrana basal
The purpose of the present study is to evaluate serological and morphologic aspects concerning the basement membrane (BM) of the thyroid follicle in autoimmune thyroid disease (ATD). In this way, new elements for ~ better understanding of its pathophisiology could be suggested. In order to detect antibodies to collagen IV and laminin, two major components of
Publicado em: 1994
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9. Is a function of the secreted hepatitis B e antigen to induce immunologic tolerance in utero?
Infants born to hepatitis B virus carrier mothers, who express a secreted form of the nucleocapsid antigen designated HBeAg, invariably become persistently infected. To investigate the role of immunologic tolerance mechanisms in chronic infection of the newborn, we have generated HBeAg-expressing transgenic mice. HBeAg-expressing transgenic mice were toleran
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10. Oral tolerance, an active immunologic process mediated by multiple mechanisms
American Society for Clinical Investigation.
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11. In search of the Holy Grail (actively acquired immunologic tolerance).
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12. A form of immunologic tolerance through impairment of germinal center development.
Primary immunization with the T-cell-dependent antigen (4-hydroxy-3-nitrophenyl)acetyl (NP) coupled to human serum albumin results in the development of two pathways of B-cell development, the extrafollicular pathway and the germinal center pathway. Soluble, deaggregated NP-human serum albumin injected before immunization results in a marked diminution of cl