Immunosuppressive Activity
Mostrando 1-12 de 229 artigos, teses e dissertações.
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1. Linear growth and bone metabolism in pediatric patients with inflammatory bowel disease
Resumo Objetivo: Revisar a fisiopatologia e os métodos de avaliação do crescimento linear e densidade mineral óssea em crianças e adolescentes com diagnóstico de doença inflamatória intestinal. Fontes dos dados: Revisão narrativa a partir de pesquisa nas bases de dados PubMed e Scopus por meio de busca ativa dos termos inflammatory bowel disease,
J. Pediatr. (Rio J.). Publicado em: 18/04/2019
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2. Polymorphisms in the TGFB1 and IL2RA genes are associated with clinical forms of leprosy in Brazilian population
BACKGROUND Leprosy is a chronic infectious disease caused by Mycobacterium leprae, and compromises the skin and peripheral nerves. This disease has been classified as multibacillary (MB) or paucibacillary (PB) depending on the host immune response. Genetic epidemiology studies in leprosy have shown the influence of human genetic components on the disease out
Mem. Inst. Oswaldo Cruz. Publicado em: 10/12/2018
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3. Circulating myeloid-derived suppressor cells predict disease activity and treatment response in patients with immune thrombocytopenia
Immune thrombocytopenia (ITP) is a disease characterized by isolated thrombocytopenia. Abnormal effector T cell activation is an important mechanism in the pathogenesis of ITP. Regulatory T cells (Treg) have a strong immunosuppressive function for T cell activation and their importance in the pathophysiology and clinical treatment of ITP has been confirmed.
Braz J Med Biol Res. Publicado em: 16/02/2017
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4. Toxicity and antitumor efficacy of Croton polyandrus oil against Ehrlich ascites carcinoma cells
ABSTRACT The essential oil from Croton polyandrus Spreng., Euphorbiaceae, leaves was tested for the toxicity and antitumor activity. The concentration producing 50% hemolysis was 141 µg/ml on mice erythrocytes. In the acute toxicological study, the estimated LD50 was 447.18 mg/kg. The essential oil did not induce increase in number of micronucleated erythro
Rev. bras. farmacogn.. Publicado em: 2016-12
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5. Osteoarthritis in horses - Part 2: a review of the intra-articular use of corticosteroids as a method of treatment
ABSTRACT: The problem considered in this review is related to the frequent use of corticosteroids (COs) (i.e. steroids) in the practice of equine medicine and surgery as a therapeutic strategy in the treatment of degenerative joint disease, commonly known as osteoarthritis (OA). This disease is one of the most common among the equine musculoskeletal diseases
Braz. arch. biol. technol.. Publicado em: 20/06/2016
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6. Chloroquine diphosphate: a risk factor for herpes zoster in patients with dermatomyositis/polymyositis
OBJECTIVES: Herpes zoster has been widely described in the context of different systemic autoimmune diseases but not dermatomyositis/polymyositis. Therefore, we analyzed the prevalence, risk factors and herpes zoster outcomes in this population. METHOD: A retrospective cohort study of herpes zoster infections in dermatomyositis/polymyositis patients was p
Clinics. Publicado em: 2013-05
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7. Fc?R e CR3 no lúpus eritematoso sistêmico: variantes polimórficas e sua influência na fagocitose e desgranulação dos neutrófilos / Fc?R and CR in systemic lupus erythematosus: polimorphisms and their influence in the phagocytosis and degranulation of neutrophils
Systemic lupus erythematosus (SLE) is an autoimmune disease in which disease-related and genetic factors and immunosuppressive and cytotoxic therapies all contribute to an increased susceptibility to infections. Factors predisposing to infection include defects in chemotaxis, abnormalities in neutrophil phagocytic activity, decreased immune complex (IC) and
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/08/2012
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8. Imunoproteção de ilhotas pancreáticas microencapsuladas em biomateriais inovadores e seu potencial terapêutico no diabetes mellitus tipo 1 / Immunoprotection of pancreatic islets microencapsulated in inovative biomaterials and its therapeutic potential in type 1 Diabetes Mellitus
Transplantation of microencapsulated islets represents an attractive therapeutical approach to treat type 1 Diabetes Mellitus, accounting for an improved glycemic control and the abolishment of immunosuppressive therapies. However, maintenance of long-term β-cell viability remains a major problem. During islet isolation, the loss of extracellular matrix
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/05/2012
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9. ATIVIDADE DE ECTOENZIMAS E DE COLINESTERASES E BIOMARCADORES DE ESTRESSE OXIDATIVO EM PACIENTES COM CÂNCER DE PULMÃO / ACTIVITY OF ECTOENZIMAS AND CHOLINESTERASES AND OXIDATIVE STRESS BIOMARKERS IN PATIENTS WITH LUNG CANCER
Lung cancer has become one of the most commonly diagnosed neoplastic diseases, as well as one of the most lethal worldwide, characterized, therefore, as a public health problem. This spread of lung cancer in the world population, which is clearly seen in statistics, is closely related to smoking, and smoking is considered one of the main risk factors that le
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2012
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10. Mechanisms of action underlying the anti-inflammatory and immunomodulatory effects of propolis: a brief review
Many biological properties have been attributed to various types of propolis, including anti-inflammatory, antimicrobial, antioxidant, antitumor, wound healing, and immunomodulatory activities. This article reviewed studies published that investigated the anti-inflammatory activity of propolis of different origins and/or its isolated components, focusing on
Revista Brasileira de Farmacognosia. Publicado em: 16/09/2011
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11. Intestinal microsporidiosis: a hidden risk in rheumatic disease patients undergoing anti-tumor necrosis factor therapy combined with disease-modifying anti-rheumatic drugs?
OBJECTIVE: Immunosuppressed patients are at risk of microsporidiosis, and this parasitosis has an increased rate of dissemination in this population. Our objective was to evaluate the presence of microsporidiosis and other intestinal parasites in rheumatic disease patients undergoing anti-tumor necrosis factor/disease-modifying anti-rheumatic drug treatment.
Clinics. Publicado em: 2011
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12. Avaliação de solução hidro alcoolica de propolis na resposta hematopoetica em camundongos infectados com Listeria monocytogenes / Evaluation of hydro alcoholic solution of propolis on the hematopoietic response in Listeria Monocytogenes
Infection with Listeria monocytogenes has proven to be a useful model to investigate early effects of new compounds on the immune response to intracellular bacteria. In particular, the number of hematopoietic cells in the bone marrow and spleen is critically important to resistance to this infection. In this study, we demonstrated the protective effects of h
Publicado em: 2009