Immunosuppressive Agents
Mostrando 1-12 de 113 artigos, teses e dissertações.
-
1. Diagnosis and treatment of latent tuberculosis infection in patients undergoing treatment with immunobiologic agents: a four-year experience in an endemic area
RESUMO Objetivo: Descrever a incidência de tuberculose ativa e a ocorrência de eventos adversos do tratamento com isoniazida em pacientes diagnosticados com tuberculose latente (TBL), portadores de doenças inflamatórias crônicas e tratados com agentes imunobiológicos em uma área endêmica no Brasil. Métodos: O diagnóstico de TBL foi feito com base
J. bras. pneumol.. Publicado em: 14/10/2019
-
2. Lichen planus with multiple system involvement including the mouth, vagina, urethra, and scalp: a case report
This is a case report of lichen planus (LP) with multiple system involvement. A 35-year-old female patient was admitted in November 2014 with a 5-year history of painful/difficult sexual intercourse and loss of oral mucosa, and an 8-year history of focal hair loss. Earlier, the patient had been unable to adhere to corticosteroid therapy because of severe adv
Braz J Med Biol Res. Publicado em: 10/10/2019
-
3. Incidence and risk factors for major infections in hospitalized children with nephrotic syndrome
RESUMO Introdução: Crianças com síndrome nefrótica apresentam maior risco de infecções devido ao próprio status da doença e ao uso de vários agentes imunossupressores. Em grande parte, as infecções desencadeiam recidivas que exigem hospitalização, com risco aumentado de morbidade e mortalidade. Este estudo teve como objetivo determinar a incid
J. Bras. Nefrol.. Publicado em: 12/09/2019
-
4. Epidemiology and clinical characteristics of herpes zoster in a tertiary care hospital in Brazil
ABSTRACT Background: There is little information on herpes zoster from hospital registries in South America. The aim of this study was to describe the epidemiological and clinical aspects of herpes zoster (HZ) in hospitalized patients.' Methods: We searched for hospital-based records during the period from March 2000 to January 2017 in a 700-bed tertiary-c
Braz J Infect Dis. Publicado em: 18/07/2019
-
5. Henoch-Schönlein purpura nephritis associated with monoclonal gammopathy of renal significance: a case report
Monoclonal gammopathy of renal significance (MGRS) can present with different morphologic features and lead to kidney failure. The Henoch-Schönlein purpura nephritis (HSPN) that cannot be relieved by treatment with glucocorticoid and immunosuppressive agents suggests the presence of monoclonal gammopathy in adult patients. The present study reports on a sin
Braz J Med Biol Res. Publicado em: 10/07/2019
-
6. Dupilumab in the treatment of severe atopic dermatitis refractory to systemic immunosuppression: case report
RESUMO Relatamos o caso de uma paciente com dermatite atópica grave, que mostrou boa resposta ao dupilumabe. Ela já tinha usado dois agentes imunossupressores, a ciclosporina A e o micofenolato de mofetila, para o tratamento da dermatite atópica, sem obter o controle adequado da doença. Ela também vinha fazendo uso de todas as medidas de controle para c
Einstein (São Paulo). Publicado em: 10/07/2019
-
7. Consensus on the therapeutic management of atopic dermatitis - Brazilian Society of Dermatology
Abstract: BACKGROUND: Atopic dermatitis is a highly prevalent inflammatory and pruritic dermatosis with a multifactorial etiology, which includes skin barrier defects, immune dysfunction, and microbiome alterations. Atopic dermatitis is mediated by genetic, environmental, and psychological factors and requires therapeutic management that covers all the aspe
An. Bras. Dermatol.. Publicado em: 03/06/2019
-
8. T cell subsets and immunoglobulin G levels are associated with the infection status of systemic lupus erythematosus patients
Systemic lupus erythematosus (SLE) is a chronic, autoimmune disorder that affects nearly all organs and tissues. As knowledge about the mechanism of SLE has increased, some immunosuppressive agents have become routinely used in clinical care, and infections have become one of the direct causes of mortality in SLE patients. To identify the risk factors indica
Braz J Med Biol Res. Publicado em: 11/12/2017
-
9. Secondary myeloid neoplasms: bone marrow cytogenetic and histological features may be relevant to prognosis
Abstract Background: Secondary myeloid neoplasms comprise a group of diseases arising after chemotherapy, radiation, immunosuppressive therapy or from aplastic anemia. Few studies have addressed prognostic factors in these neoplasms. Method: Forty-two patients diagnosed from 1987 to 2008 with secondary myeloid neoplasms were retrospectively evaluated conce
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-03
-
10. Methotrexate and etanercept-induced primary cutaneous CD4 positive small/medium-sized pleomorphic T-cell lymphoma
Abstract: Immunosuppressive drugs and biological agents may represent a potential risk of lymphoma development in patients with rheumatoid arthritis. But most cases are diffuse, large B-cell lymphomas. Primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma, a provisional entity in the 2005 WHO-EORTC classification of cutaneous lymphomas, is on
An. Bras. Dermatol.. Publicado em: 2016-06
-
11. Refractory pemphigus vulgaris treated with rituximab and mycophenolate mofetil
The main treatment for pemphigus vulgaris are systemic corticosteroids and immunosuppressive agents, but due to adverse reactions and therapeutic failure, new drugs such as rituximab and mycophenolate mofetil have been used. In this case report are described two cases of severe pemphigus vulgaris refractory to various treatments, with resolution after use of
An. Bras. Dermatol.. Publicado em: 2014-12
-
12. New immunosuppressive agents in pediatric transplantation
Immunosuppressive therapy in pediatrics continues to evolve. Over the past decade, newer immunosuppressive agents have been introduced into adult and pediatric transplant patients with the goal of improving patient and allograft survival. Unfortunately, large-scale randomized clinical trials are not commonly performed in children. The purpose of this review
Clinics. Publicado em: 2014-01