In Vitro In Vivo Correlation
Mostrando 1-12 de 497 artigos, teses e dissertações.
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1. Comparison of Volatile Profile and Antioxidant Activity of Piper divaricatum G. Meyer (Piperaceae) Using Cuttings and Cell Tissue
In this study, P. divaricatum (Piperaceae) plants were subcultured by cuttings and cell tissue in order to carry out a comparison of the volatile profile, phenolic compounds, and antioxidant activity. Propagation by cuttings used vermiculite substrate and Murashige-Skoog (MS) medium in the absence of growth regulators and rooting started at 15 days of growth
J. Braz. Chem. Soc.. Publicado em: 24/10/2019
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2. Occurrence, antifungal susceptibility, and virulence factors of opportunistic yeasts isolated from Brazilian beaches
BACKGROUND Opportunistic pathogenic yeast species are frequently associated with water habitats that have pollution sources of human or animal origin. Candida albicans has already been suggested as a faecal indicator microorganism for aquatic environments. OBJECTIVES The goal of this study was to investigate the occurrence of C. albicans and other opport
Mem. Inst. Oswaldo Cruz. Publicado em: 14/03/2019
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3. Preparation and in vitro & in vivo evaluation of cephalexin matrix tablets
The purpose of the study is to develop cephalexin controlled-release matrix tablets by using lower proportions of release retardant polymer and to establish their in vitro & in vivo correlation. Tablets were compressed by incorporating polymers in a matrix form along with drug which prolong the drug release. Twelve formulations were prepared by mixing ethyl
Braz. J. Pharm. Sci.. Publicado em: 29/11/2018
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4. Estimating the mechanical competence parameter of the trabecular bone: a neural network approach
Abstract Introduction The mechanical competence parameter (MCP) of the trabecular bone is a parameter that merges the volume fraction, connectivity, tortuosity and Young modulus of elasticity, to provide a single measure of the trabecular bone structural quality. Methods As the MCP is estimated for 3D images and the Young modulus simulations are quite cons
Res. Biomed. Eng.. Publicado em: 07/07/2016
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5. Comparative HPTLC analysis of bioactive marker barbaloin from in vitro and naturally grown Aloe vera
ABSTRACT Aloe vera (L.) Burm. f., Xanthorrhoeaceae, a succulent, produces barbaloin, a bioactive compounds used in various pharmaceutical products. Extracts prepared from the leaves have been widely used as bittering agents, taste modifiers and also as cathartic agent against severe constipation. Barbaloin is reported for its anti-inflammatory, anticancer, a
Rev. bras. farmacogn.. Publicado em: 2016-04
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6. Identification and adhesion profile of Lactobacillus spp. strains isolated from poultry
In the aviculture industry, the use of Lactobacillus spp. as a probiotic has been shown to be frequent and satisfactory, both in improving bird production indexes and in protecting intestine against colonization by pathogenic bacteria. Adhesion is an important characteristic in selecting Lactobacillus probiotic strains since it impedes its immediate eliminat
Braz. J. Microbiol.. Publicado em: 2014-09
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7. Correlation of phospholipase and proteinase production of Candida with in vivo pathogenicity in Galleria mellonella
An essential factor to the virulence of the genus Candida is the ability to produce enzymes and this may be crucial in the establishment of fungal infections. AIM:This study investigated in vitro enzymatic activities of Candida species and their virulence in an in vivo Galleria mellonella experimental model. METHODS: Twenty-four clinical strains of Candida s
Braz. J. Oral Sci.. Publicado em: 2013-09
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8. Doenças quiescentes em goiabas: quantificação e controle pós-colheita / Quiescent diseases in guava: quantification and post-harvest control
Post-harvest diseases in guavas may represent damages from 20 to 40%. Environmental conditions and disease management, before or after harvesting, are among their major causes. Standards proposed by the Integrated Production Fruit (IPF) ensure fruit quality and sustainable production with rational use of agrochemicals. Using the white-fleshed variety Kumagai
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/11/2012
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9. Validação de correlação in vitro-in vivo para comprimidos de liberação modificada de diclofenaco de sódio / Validation of in vivo-in vitro correlation for modified release tablet containing sodium diclofenac
A dissolução de fármacos administrados por via oral é pré-requisito para sua absorção e eficácia clínica. Esta constatação fornece a base para as tentativas de estabelecer correlações entre a dissolução in vitro e a biodisponibilidade in vivo de medicamentos, denominadas correlações in vitro - in vivo (CIVIV). As correlações in vitro-in vi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/03/2012
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10. Comparative analysis of the intracerebral mouse protection test and serological method for potency assays of pertussis component in DTP vaccine
The aim of this study was to compare the PSPT standardized in-house as an alternative to MPT for potency assays of pertussis component. Statistical analyses have showed similar pertussis potency values when PSPT was compared to MPT. Significant correlation between the potency results obtained by in vivo and in vitro assays was also been observed. Results by
Brazilian Journal of Microbiology. Publicado em: 2012-06
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11. Determination of in vivo toxicity and in vitro cytotoxicity of venom from the Cypriot blunt-nosed viper Macrovipera lebetina lebetina and antivenom production
The venomous Levantine viper, Macrovipera lebetina lebetina is endemic to Cyprus. The objective of this study was to investigate in vitro cytotoxicity, in vivo lethality, and antivenom production followed by a re-immunization schedule in mice against Macrovipera lebetina lebetina venom. The LD50 value was estimated as 7.58 mg/kg within 24 hours by different
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2012
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12. Avaliação clínica, histológica e imunológica de enxertos ósseos alógenos fresco-congelados utilizados como técnica na preservação de rebordo alveolar pós-extração / Preservation of alveolar bone in extraction sockets using fresh-frozen bone allograft: a clinical, histological and immunological study
The fresh-frozen bone allograft (FFBA) is an alternative to surgical procedures of bone grafts, mainly in the preservation of alveolar ridge prior the installation of osseointegrated implants. However there are paradigms that surround the relation between immune response to alloantigens present inside the graft and the clinical response of the graft. An atte
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/09/2011