Inhibitory Peptide
Mostrando 1-12 de 664 artigos, teses e dissertações.
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1. Antinociceptive effect of PnTx4(5-5), a peptide from Phoneutria nigriventer spider venom, in rat models and the involvement of glutamatergic system
ABSTRACT Background: The venom of Phoneutria nigriventer spider is a source of numerous bioactive substances, including some toxins active in insects. An example is PnTx4(5-5) that shows a high insecticidal activity and no apparent toxicity to mice, although it inhibited NMDA-evoked currents in rat hippocampal neurons. In this work the analgesic activity o
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 12/08/2019
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2. Evaluation antibacterial and antibiofilm activity of the antimicrobial peptide P34 against Staphylococcus aureus and Enterococcus faecalis
ABSTRACT The adhesion ability of bacteria to abiotic surfaces has important implications in food industries, because these organisms can survive for long periods through the biofilm formation. They can be transferred from one place to another in the industry causing contamination of the food processing environment. In this study, the antibacterial and antibi
An. Acad. Bras. Ciênc.. Publicado em: 01/02/2018
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3. Comparison of some functionalities of water soluble peptides derived from Turkish cow and goat milk Tulum cheeses during ripening
Abstract In this study, profiles and functional properties such as antioxidant, mineral binding, and antimicrobial activities of water-soluble peptides from Turkish goat milk Tulum cheese and cow milk Tulum cheese were examined during the ripening period. According to the results of RP-HPLC, the number of peptides increased as the ripening days progressed du
Food Sci. Technol. Publicado em: 21/09/2017
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4. Synthesis, Characterization and in vitro Antioxidant Activity of New Chiral N-boc Organotellurium Compounds, (CH3)3OC(O)NHCH(R)C(O)NHCH2-CH2Te-C6H4-4-OCH3, Containing Carbamate and Peptide Groups
Synthesis, characterization and antioxidant activity of a new series of chiral N-boc oraganotellurium compounds, (CH3)3OC(O)NHCH(R)C(O)NHCH2CH2Te-C6H4-4-OCH3, containing carbamate and peptide groups have been reported in this paper. These chiral peptides were synthesized in good to excellent yields, via acid-amine coupling reaction of N-boc L-amino acids wit
J. Braz. Chem. Soc.. Publicado em: 2016-06
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5. Cloning and purification of the first termicin-like peptide from the cockroach Eupolyphaga sinensis
Abstract Background Termicin is an antimicrobial peptide with six cysteines forming three disulfide bridges that was firstly isolated from the salivary glands and hemocytes of the termite Pseudacanthotermes spiniger. In contrast to many broad-spectrum antimicrobial peptides, termicin is most active against filamentous fungi. Although more than one hundred
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 19/02/2016
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6. Cinerascetins, New Peptides from Hypsiboas cinerascens: MALDI LIFT-TOF-MS/MS de novo Sequence and Imaging Analysis
The continuous search for antimicrobial candidates pushes the pursuit of compounds in the most diverse organisms. Amphibians are known as a prolific source of antibacterial peptides. Based on the rich biodiversity of the Amazon region the unexplored green-tree frog (Hypsiboas cinerascens) was studied for its skin secretion peptide content. Chromatographic se
J. Braz. Chem. Soc.. Publicado em: 2015-11
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7. ACE-I inhibitory properties of hydrolysates from germinated and ungerminated Phaseolus lunatus proteins
Phaseolus lunatus protein concentrates and the proteases Alcalase(R) and Pepsin-Pancreatin were used for the production of protein hydrolysates that inhibit angiotensin-I converting enzyme (ACE). Protein concentrate obtained from germinated and ungerminated seeds flour was hydrolyzed with Alcalase(R) at enzyme/substrate ratio (E/S) 1/10 and during 0.5 and 2.
Food Sci. Technol. Publicado em: 2015-03
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8. Analysis of whey protein hydrolysates: peptide profile and ACE inhibitory activity
O objetivo deste estudo foi preparar hidrolisados enzimáticos do concentrado proteico do soro de leite com perfil peptídico nutricionalmente adequado e com capacidade para inibir a atividade da enzima conversora da angiotensina (ECA). Os efeitos do tipo de enzima usado (pancreatina ou papaína), da relação enzima:substrato (E:S=0,5:100, 1:100, 2:100 e 3:
Braz. J. Pharm. Sci.. Publicado em: 2012-12
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9. Secretory TAT-peptide-mediated protein transduction of LIF receptor α-chain distal cytoplasmic motifs into human myeloid HL-60 cells
The distal cytoplasmic motifs of leukemia inhibitory factor receptor α-chain (LIFRα-CT3) can independently induce intracellular myeloid differentiation in acute myeloid leukemia (AML) cells by gene transfection; however, there are significant limitations in the potential clinical use of these motifs due to liposome-derived genetic modifications. To produce
Braz J Med Biol Res. Publicado em: 2012-10
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10. Diversidade e atividade antimicrobiana de bactérias isoladas de esponjas marinhas / Diversity and antimicrobial activity of bacteria isolated from marine sponges
Nas últimas décadas um grande número de compostos de interesse biotecnológico, como por exemplo, citotoxinas, agentes antifúngicos, antimicrobianos, antivirais e anticancerígenos têm sido isolados de esponjas marinhas. Entretanto, estudos comprovam que, em muitos casos, os compostos ativos desses animais são oriundos de micro-organismos associados, q
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 04/05/2011
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11. Obtenção de hidrolisados enzimáticos do concentrado protéico do soro de leite com alto teor de oligopeptídeos e elevada atividade inibitória sobre a enzima conservadora de angiotensina, utilizando a pancreatina e a papaína
PREPARATION OF ENZYMATIC HYDROLYSATES WITH HIGH OLIGOPEPTIDE CONTENT AND ANGIOTENSIN-CONVERTING ENZYME INHIBITORY ACTIVITY FROM WHEY PROTEIN CONCENTRATE USING PANCREATIN AND PAPAIN. Protein hydrolysates have been used in clinical practice in the manufacture of special foods for individuals with special physiological and nutritional needs. Thus, the aim of th
Publicado em: 2010
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12. Proteína quinase C (PKC) e proteína quinase dependente de cálcio/calmodulina (CaMK II) na ativação de oócitos bovinos / Protein kinase C (PKC) and Calcium/calmodulin-dependent protein kinase II (CaMKII) in bovine oocyte activation
A fecundação resulta no aumento intracelular de cálcio que é necessário para a transição do oócito até o estádio de zigoto. Os eventos que ocorrem durante esta transição são caracterizados como ativação, sendo estes dependentes de cálcio. Entretanto, os eventos bioquímicos que ocorrem durante a ativação ainda não estão completamente eluc
Publicado em: 2010