Insensitivity
Mostrando 1-12 de 479 artigos, teses e dissertações.
-
1. Total corpora mobilization for penile reconstruction
ABSTRACT Purpose: Total corpora mobilization (TCM) is a novel technique that is used for penile reconstruction in cases of micropenis and penile amputation. Its principle is based on Kelly’s procedure for bladder exstrophy (1). In contrast to the Kelly procedure, TCM is performed entirely through the perineum with the patient in the lithotomy position. M
International braz j urol. Publicado em: 2022
-
2. Leydig and Sertoli cell function in individuals with genital ambiguity, 46,XY karyotype, palpable gonads and normal testosterone secretion: a case-control study
Abstract BACKGROUND: Because normal male sexual differentiation is more complex than normal female sexual differentiation, there are more cases of disorders of sex development (DSDs) with 46,XY karyotype that have unclear etiology. However, Leydig and Sertoli cell markers are rarely used in distinguishing such individuals. OBJECTIVES: To evaluate the funct
Sao Paulo Medical Journal. Publicado em: 2022
-
3. Evaluation of nuclear NF-κB, transglutaminase2, and ERCC1 as predictors of platinum resistance in testicular tumors
ABSTRACT Purpose: Testicular germ cells tumor (TGCT) are associated with a high cure rate and are treated with platinum-based chemotherapy. However, a group of testicular cancer patients may have a very unfavorable evolution and insensitivity to the main therapeutic agent chemotherapy (CT) cisplatin. The aim of this study was to evaluate the risk of recurre
Int. braz j urol.. Publicado em: 2020-06
-
4. Growth Hormone insensitivity (Laron syndrome): Report of a new family and review of Brazilian patients
Abstract Laron’s syndrome (LS) is a rare genetic disorder characterized by insensitivity to growth hormone (GH). Up to the present time, over 70 mutations of GH receptor (GHR) gene have been identified leading to GH/insulin-like growth factor type 1 (IGF1) signaling pathway defect. The number of LS patients worldwide is unknown, as many are probably undiag
Genet. Mol. Biol.. Publicado em: 20/01/2020
-
5. Imigração, a morte dos não-humanos e a idolatria
Resumo A partir de dois casos de criminalização dos voluntários que ajudaram imigrantes irregulares em situações de perigo de morte, o artigo analisa o processo de inversão da consciência moral, que consiste em interpretar uma ação solidária como um crime de traição e atentado contra a segurança nacional. Para isso, a partir da noção de oferta
REMHU, Rev. Interdiscip. Mobil. Hum.. Publicado em: 02/12/2019
-
6. [PROVISIONAL] Growth Hormone Insensitivity (Laron syndrome): report of a new family and review of Brazilian patients
Genet. Mol. Biol.. Publicado em: 12/08/2019
-
7. Enzymatic Properties and Ryegrass Resistance Mechanism to Iodosulfuron-Methyl-Sodium Herbicide
RESUMO: O azevém (Lolium multiflorum) é uma das espécies mais preocupantes em relação à resistência aos herbicidas. Este estudo objetivou caracterizar a atividade da enzima acetolactato sintase (ALS) de biótipos resistentes (NC e AR) e suscetível de azevém ao herbicida iodosulfurom-metílico sódio (iodosulfurom). Diferentes concentrações de piru
Planta daninha. Publicado em: 18/02/2019
-
8. THEORETICAL STUDIES ON TRIACETONETRIPEROXIDE (TATP) DERIVATIVES TO IMPROVE THEIR PERFORMANCE
Density functional theory (DFT) methods are used to study on TATP derivatives at DFT-B3LYP/6-311++G (d, p) level to improve TATP’s performance. The derivatives are 3,6,9-trimethyl-3,6,9-tris(trifluoromethyl)-1,2,4,5,7,8-hexaoxonane (TATP3F), 3,6,9-trimethyl-3,6,9-tris(nitromethyl)-1,2,4,5,7,8-hexaoxonane (TATPNO2) and (3,6,9-trimethyl-1,2,4,5,7,8-hexaoxona
Quím. Nova. Publicado em: 2019-01
-
9. Saquinavir plus methylprednisolone ameliorates experimental acute lung injury
Glucocorticoid insensitivity is an important barrier to the treatment of several inflammatory diseases, including acute lung injury (ALI). Saquinavir (SQV) is an inhibitor of the human immunodeficiency virus protease, and the therapeutic effects of SQV in ALI accompanied with glucocorticoid insensitivity have not been previously investigated. In this study,
Braz J Med Biol Res. Publicado em: 06/08/2018
-
10. Androgen insensitivity syndrome: a review
ABSTRACT Androgenic insensitivity syndrome is the most common cause of disorders of sexual differentiation in 46,XY individuals. It results from alterations in the androgen receptor gene, leading to a frame of hormonal resistance, which may present clinically under 3 phenotypes: complete (CAIS), partial (PAIS) or mild (MAIS). The androgen receptor gene has 8
Arch. Endocrinol. Metab.. Publicado em: 2018-03
-
11. What are 'Think Tanks'? Revisiting the Dilemma of the Definition
'Think tanks' (TTs) are 'sui generis' organizations that have been proliferating, playing more and more the role of very relevant actors on the political scene in clashes over interests, preferences and ideas for the formation of public policies. The definition of 'think tank', however, creates a conceptual gap that causes serious limitations on the developm
Bras. Political Sci. Rev.. Publicado em: 27/07/2017
-
12. Growth hormone insensitivity with immune dysfunction caused by a STAT5B mutation in the south of Brazil: evidence for a founder effect
ABSTRACT Homozygous STAT5B mutations causing growth hormone insensitivity with immune dysfunction were described in 10 patients since 2003, including two Brazilian brothers from the south of Brazil. Our objectives were to evaluate the prevalence of their STAT5B mutation in this region and to analyze the presence of a founder effect. We obtained DNA samples f
Genet. Mol. Biol.. Publicado em: 05/06/2017