Insulin Like Growth Factor Binding Proteins
Mostrando 1-12 de 96 artigos, teses e dissertações.
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1. Laboratory investigations in the diagnosis and follow-up of GH-related disorders
ABSTRACT In addition to auxiological, clinical and metabolic features measurements of growth hormone (GH) and insulin-like growth factor I (IGF-I) complement our tools in diagnosis and follow-up of GH-related disorders. While comparably robust during the pre-analytical phase, measurement and interpretation of concentrations of both hormones can be challengin
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
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2. Metabolic, productive and reproductive responses to postpartum short-term supplementation in primiparous beef cows
The objective of this study was to evaluate the effect of a short-term supplementation with rice bran (2 kg/cows/day) on the endocrine and metabolic profiles and hepatic gene expression, associated with the reproductive response in beef cows in grazing conditions. Thirty-eight primiparous beef cows (Hereford, Angus and Hereford × Angus) were used in a rando
R. Bras. Zootec.. Publicado em: 2013-04
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3. Cycle modulation of insulin-like growth factor-binding protein 1 in human endometrium
Endometrium is one of the fastest growing human tissues. Sex hormones, estrogen and progesterone, in interaction with several growth factors, control its growth and differentiation. Insulin-like growth factor 1 (IGF-1) interacts with cell surface receptors and also with specific soluble binding proteins. IGF-binding proteins (IGF-BP) have been shown to modul
Publicado em: 2010
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4. Estudo do efeito de sobrevivência promovido pelo Mycobacterium leprae sobre as células de Schwann: análise do envolvimento dos fatores semelhantes à insulina (IGFs) e da via PI 3-K/Akt. / Study of the effect of survival promoted for the Mycobacterium leprae on the Schwann cell: analysis of the envolvement of the similar factors to the insulin (IGFs) and of way PI 3-K/Akt.
A hanseníase é uma doença crônica causada pelo bacilo Mycobacterium leprae, um patógeno intracelular obrigatório, cujo principal alvo são as células de Schwann (CS), tendo como consequências mais significativas a perda funcional dos nervos periféricos e deformidades. É sabido que patógenos intracelulares bloqueiam vias de apoptose na célula hosp
Publicado em: 2008
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5. Cycle modulation of insulin-like growth factor-binding protein 1 in human endometrium
Endometrium is one of the fastest growing human tissues. Sex hormones, estrogen and progesterone, in interaction with several growth factors, control its growth and differentiation. Insulin-like growth factor 1 (IGF-1) interacts with cell surface receptors and also with specific soluble binding proteins. IGF-binding proteins (IGF-BP) have been shown to modul
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-11
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6. Solution structure of human insulin-like growth factor II; recognition sites for receptors and binding proteins.
The three-dimensional structure of human insulin-like growth factor II was determined at high resolution in aqueous solution by NMR and simulated annealing based calculations. The structure is quite similar to those of insulin and insulin-like growth factor I, which consists of an alpha-helix followed by a turn and a strand in the B-region and two antiparall
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7. Insulin-like growth factors and insulin-like growth factor binding proteins in mammary gland function
Insulin-like growth factor (IGF)-mediated proliferation and survival are essential for normal development in the mammary gland during puberty and pregnancy. IGFs interact with IGF-binding proteins and regulate their function. The present review focuses on the role of IGFs and IGF-binding proteins in the mammary gland and describes how modulation of their act
BioMed Central.
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8. Insulin-like growth factor binding proteins from cultured human fibroblasts. Characterization and hormonal regulation.
Specific, high affinity insulin-like growth factor (IGF) binding proteins are secreted by human fibroblasts in culture. By multiple criteria, the species of IGF binding proteins produced by human fibroblasts are distinct from the HepG2/amniotic fluid IGF binding protein, but share many characteristics with the growth hormone-dependent IGF binding protein for
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9. Hybrid molecules containing the B-domain of insulin-like growth factor I are recognized by carrier proteins of the growth factor.
The insulin-like growth factors (IGFs) are polypeptides in plasma that are chemically related to insulin and have mitogenic and insulin-like activity. Unlike insulin, the IGFs circulate in plasma bound to specific high molecular weight carrier proteins that regulate their delivery to target tissues. To define the sites on the IGFs that allow them to be recog
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10. Role of Insulin-like Growth Factor Binding Protein-3 in Allergic Airway Remodeling
Rationale: The hallmarks of allergic asthma are airway inflammation, obstruction, and remodeling. Airway remodeling may lead to irreversible airflow obstruction with increased morbidity and mortality. Despite advances in the treatment of asthma, the mechanisms underlying airway remodeling are still poorly understood. We reported that insulin-like growth fact
American Thoracic Society.
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11. Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily
The insulin-like growth factor (IGF) binding proteins (IGFBPs) modulate the actions of the insulin-like growth factors in endocrine, paracrine, and autocrine settings. Additionally, some IGFBPs appear to exhibit biological effects that are IGF independent. The six high-affinity IGFBPs that have been characterized to date exhibit 40–60% amino acid sequence
The National Academy of Sciences of the USA.
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12. A Family of Insulin-Like Growth Factor II mRNA-Binding Proteins Represses Translation in Late Development
Insulin-like growth factor II (IGF-II) is a major fetal growth factor. The IGF-II gene generates multiple mRNAs with different 5′ untranslated regions (5′ UTRs) that are translated in a differential manner during development. We have identified a human family of three IGF-II mRNA-binding proteins (IMPs) that exhibit multiple attachments to the 5′ UTR f
American Society for Microbiology.