Interferon Alpha Receptor
Mostrando 1-12 de 293 artigos, teses e dissertações.
-
1. Correlation between the cytokine profile and anticongestive medication in patients with chronic chagasic cardiopathy
Abstract INTRODUCTION: Chronic chagasic cardiopathy (CCC) is essentially a dilated cardiomyopathy in which a subacute, but constant chronic inflammatory process causes progressive destruction of the heart tissue. The action of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-α), interferon gamma (IFN-γ), and anti-inflammatory cytokines,
Rev. Soc. Bras. Med. Trop.. Publicado em: 02/12/2019
-
2. Profile of HIV subtypes in HIV/HBV- and HIV/HCV-coinfected patients in Southern Brazil
Abstract INTRODUCTION: HIV and viral hepatitis infections are major causes of chronic disease worldwide and have some similarities with regard to routes of transmission, epidemiology, front barriers faced during access of treatment, and strategies for a global public health response. The objective was to describe the HIV-1 subtypes, viral tropism and single
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-08
-
3. Bacillus Coagulans Enhance the Immune Function of the Intestinal Mucosa of Yellow Broilers
ABSTRACT This experiment was conducted to investigate the effects of Bacillus coagulans on the growth performance and immune functions of the intestinal mucosa of yellow broilers. Three hundred and sixty one-day-old yellow chicks were randomly allocated to four treatments groups with six replicates of 15 chicks each. The broilers were randomly subjected to o
Rev. Bras. Cienc. Avic.. Publicado em: 2017-03
-
4. In vitro study of the effect of a probiotic bacterium Lactobacillus rhamnosus against herpes simplex virus type 1
BACKGROUND: Due to the emergence of drug resistance in herpes simplex virus type 1 (HSV-1), researchers are trying to find other methods for treating herpes simplex virus type 1 infections. Probiotic bacteria are effective in macrophage activation and may have antiviral activities. OBJECTIVE: This study aimed at verifying the direct effect of Lactobacillus r
Brazilian Journal of Infectious Diseases. Publicado em: 2012-04
-
5. Caracterização fenotípica e grau de ativação de células dendríticas plasmocitóides ao estímulo in vitro com oligodeoxinucleotídeos CpG na urticária crônica / Phenotypic characterization and degree of activation of plasmacytoid dendritic cells induced by oligodeoxynucleotides CpG in chronic idiopathic urticaria
INTRODUÇÃO: A urticária crônica é caracterizada pelo aparecimento de placas eritêmato-edematosas, pruriginosas que perduram por mais de seis semanas. A investigação da imunidade inata é de grande importância para a compreensão da imunopatologia de doenças dermatológicas crônicas como a Urticária Crônica Idiopática (UCI). Entre os componentes
Publicado em: 2011
-
6. Expressão local de interferon alfa, dos receptores de interferon alfa (IFNAR) e da enzima 25Oligoadenilato sintetase em pacientes com neoplasia intraepitelial cervical
Interferor-alfa (IFN-α) is a glicoprotein belonged to a family of cytokines which participate in the control and cell replication in the defence of hostess against strange organisms, as vírus or bacteria. Although the IFN-α has been known by antiviral property, numerous investigations afterward showed that the IFN is involved on regulation cell gr
Publicado em: 2008
-
7. Analisys of polymorphism of KIR in patients with chronic C hepatitis. / Análise do polimorfismo do KIR em pacientes com hepatite crônica C submetidos à terapia antiviral.
The treatment of chronic hepatitis C is carried out using different types of alpha interferon associated to ribavirin. Factors such as viral genotype, viral load and characteristics of the host are important in the success of the therapy. Factors associated to the host such as immunologic and genetic may also have an important role in the treatment of hepati
Publicado em: 2007
-
8. Interferon-alpha receptor 1 mRNA expression in peripheral blood mononuclear cells is associated with response to interferon-alpha therapy of patients with chronic hepatitis C
Interferon (IFN)-alpha receptor mRNA expression in liver of patients with chronic hepatitis C has been shown to be a response to IFN-alpha therapy. The objective of the present study was to determine whether the expression of mRNA for subunit 1 of the IFN-alpha receptor (IFNAR1) in peripheral blood mononuclear cells (PBMC) is associated with the response to
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-05
-
9. Detection of circulant tumor necrosis factor-alpha , soluble tumor necrosis factor p75 and interferon-gamma in Brazilian patients with dengue fever and dengue hemorrhagic fever
Pro-inflammatory cytokines are believed to play an important role in the pathogenesis of dengue infection. This study reports cytokine levels in a total of 54 patients examined in Recife, State of Pernambuco, Brazil. Five out of eight patients who had hemorrhagic manifestations presented tumor necrosis factor-alpha (TNF-alpha) levels in sera which were stati
Memórias do Instituto Oswaldo Cruz. Publicado em: 2001-02
-
10. Expression and biological activity of two recombinant polypeptides related to subunit 1 of the interferon-a receptor
Abnormal production of interferon alpha (IFN-a) has been found in certain autoimmune diseases and can be also observed after prolonged therapy with IFN-a. IFN-a can contribute to the pathogenesis of allograft rejection in bone marrow transplants. Therefore, the development of IFN-a inhibitors as a soluble receptor protein may be valuable for the therapeutic
Brazilian Journal of Medical and Biological Research. Publicado em: 2000-07
-
11. Characterization of three monoclonal antibodies that recognize the interferon alpha 2 receptor.
The interferon system plays an important role in the control of viral infections and cell proliferation. These effects are mediated through the interaction of interferons with specific cell surface receptors. We report here the development of monoclonal antibodies against one of the subunits of the interferon alpha receptor. These antibodies detect a 110-kDa
-
12. Recombinant interferon alpha can induce rearrangement of T-cell antigen receptor alpha-chain genes and maturation to cytotoxicity in T-lymphocyte clones in vitro.
T-cell receptor genes are found in the germ-line configuration as well as in rearranged forms, as detected in T lymphocytes by different patterns in Southern blot analysis. We have recently shown that cytotoxic T-lymphocyte (CTL) "precursor" clones, in which rearrangements are not detected in the gene encoding the T-cell receptor alpha-chain (TCRA), acquire