Interferon Type Ii
Mostrando 1-12 de 192 artigos, teses e dissertações.
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1. Células dendríticas plasmocitoides, dendrócitos dérmicos fator XIIIa positivos, macrófagos e expressão da forma induzida da óxido nítrico sintase na resposta tecidual cutânea de leishmaniose tegumentar americana / Plasmacytoid dendritic cells, Factor XIIIa-positive dermal dendrocytes, macrophages and inducible nitric oxide synthase expression in American tegumentary leishmaniasis skin lesions
Em todas as formas clínicas da leishmaniose tegumentar americana os macrófagos são as células efetoras mais importantes na destruição do parasita intracelular. As células dendríticas são células apresentadoras de antígeno localizadas nos sítios de inoculação, como pele e mucosa. Os dendrócitos dérmicos Fator XIIIa positivos são células deri
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 10/08/2012
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2. Estudos neuroimunológicos da doença de Chagas experimental. Análises histomoleculares da medula espinal de camundongos imunocompetentes e deficientes em IL-12 e IL-23 infectados com Trypanosoma cruzi da cepa Sylvio X10/4. / Neuroimmunological studies of experimental Chagas\ disease. Histomolecular analysis of the spinal cord of immunecompetent and immunedeficient mice that have been infected with parasites of Sylvio X10/4 strain of Trypanosoma cruzi.
O estabelecimento de uma resposta TH1 com a produção de IL-12, IFN-gama e de óxido nítrico é crucial no controle do Trypanosoma cruzi, o qual pode colonizar o SNC de crianças e pacientes imunossuprimidos. A inflamação exacerbada em decorrência da persistência de um estímulo antigênico gera o acúmulo de substâncias potencialmente citotóxicas, c
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/08/2011
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3. Determinação da sensibilidade e especificidade de teste de liberação de interferon-gama por linfócitos ativos estimulados por antígenos específicos do Mycobacterium tuberculosis em crianças / Evaluation of the sensibility and the specificity of an interferon-gamma release assay after lymphocyte stimulation by specific Mycobacterium tuberculosis antigens in children
INTRODUÇÃO: A tuberculose é um problema grave de saúde pública, acometendo indivíduos em todas as faixas etárias e em todos os estratos socioeconômicos. Apesar de estarem sob grande risco de adoecimento, as crianças carecem de meios diagnósticos sensíveis e específicos. Neste estudo avaliou-se em crianças a acurácia de um teste baseado na dosag
Publicado em: 2009
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4. The use of monoclonal antibody (Rituximab) in the treatment of type II mixed cryoglobulinemia
Anti-CD20 monoclonal antibody has been successfully used to treat several self-immune diseases. The authors report the case of a 71 year-old female patient under the use of pegylated form of interferon á associated with ribavirin for the treatment of hepatitis C, who, after concluding the therapeutic program - negative Polymerase Chain Reaction (PCR) - deve
Brazilian Journal of Infectious Diseases. Publicado em: 2007-02
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5. Tuberculose pulmonar: aumento da eficiência diagnóstica pela associação de métodos microbiológicos e imunológicos para pesquisa de anticorpos IgG anti - Mycobacterium tuberculosis por Western blotting e interferon-gama / Pulmonary tuberculosis: enhanced efficiency diagnostic combining microbiological and immunological methods to detect IgG anti Mycobacterium tuberculosis antibodies by Western blotting and interferon-gamma
Tuberculosis remains a major public-health problem. Rapid diagnosis and prompt treatment is the cornerstone to reduce morbidity, mortality and incidence of tuberculosis in the world. Alternative methods have been developed to overcome the limitations presented by conventional microbiological methods and to improve the diagnosis and prognosis of tuberculosis.
Publicado em: 2007
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6. IFN-y production in patients with leprosy and in yours households in the populacional sample of the Sobral city- Ceara. / ProduÃÃo de ifn-y em pacientes com hansenÃase e em seus contactantes numa amostra populacional do MunicÃpio de Sobral - CearÃ
Leprosy, which is caused by Mycobacterium leprae, is an illness of ample clinical and immunopathological spectrum. Its clinical manifestations are correlated with distinct immunologic form, varying from a vigorous immune response mediated by cells to M. leprae, with type 1 standard in the tuberculÃide polar region, to an absence of specific cellular respons
Publicado em: 2007
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7. Cytokine profile associated with human chronic schistosomiasis mansoni
This study objective was to evaluate the cytokines associated with early events of hepatic fibrosis in schistosomiasis mansoni. Hepatic fibrosis was classified by ultrasonography in 94 patients. Immunological evaluation was performed by measurement of secreted cytokines (interleukin IL-5, IL-10, IL-13, interferon-gamma, tumor necrosis factor-alpha and transf
Memórias do Instituto Oswaldo Cruz. Publicado em: 2004-08
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8. Differential efficacies of human type I and type II interferons as antiviral and antiproliferative agents.
Treatment of human fibroblast FS-4 cultures with human type II interferon preparations induced the synthesis of at least four proteins that were similar in size to four of the five proteins induced by type I interferons (Mr 120,000, 88,000, 67,000, and 56,000). However, the Mr 67,000 and 56,000 proteins were induced more strongly by type II than by type I in
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9. Mouse fibroblast (type I) and immune (type II) interferons: pronounced differences in affinity for gangliosides and in antiviral and antigrowth effects on mouse leukemia L-1210R cells.
Different interferons can be obtained from the same animal species depending on the cells and (or) the inducers used. Interferons of type I and type II differ not only antigenically but also in molecular weight and stability at low pH. We have investigated whether mouse type I and type II interferons also differ in properties relating to their biological act
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10. Type II interferon induction and passive transfer depress the murine cytochrome P-450 drug metabolism system.
Induction of type II interferon by sensitization of mice with Mycobacterium tuberculosis strain BCG and challenge with tuberculin resulted in a depression of the cytochrome P-450 drug metabolism system of the liver. The degree of depression was significantly greater than in mice that were only sensitized to BCG. Cytochrome b5 levels were not affected. In add
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11. Dissection of the interferon gamma-MHC class II signal transduction pathway reveals that type I and type II interferon systems share common signalling component(s).
We have used a herpes virus thymidine kinase (HSV-TK) based metabolic selection system to isolate mutants defective in the interferon gamma mediated induction of the MHC class II promoter. All the mutations act in trans and result in no detectable induction of MHC and invariant chain (Ii) gene expression. Scatchard analysis indicates that the mutants have a
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12. Cellular source of interferons in the circulation of mice with delayed hypersensitivity.
The cellular origins of type I and type II interferons released into the circulation of mice with delayed hypersensitivity were investigated. We determined the effect of treatment with various immunosuppressive agents, including cyclophosphamide, cycloheximide, antithymocyte serum, and whole-body X-irradiation, on the release of interferons after intravenous