Intervertebral Disc
Mostrando 1-12 de 86 artigos, teses e dissertações.
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1. Facet Tropism/Inclination and Its Association with Intervertebral Disc Herniation in the Lumbar Spine – A Radiological Evaluation
Resumo Objetivo Avaliar o papel do tropismo facetário (TF) no prolapso discal intervertebral. Métodos Um total de 98 pacientes com dor lombar foram incluídos no estudo. Exames de ressonância magnética foram realizados e analisados, e os ângulos das facetas direita e esquerda foram medidos na seção axial. Os pacientes sem prolapso discal nos níveis
Revista Brasileira de Ortopedia. Publicado em: 2022
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2. Nuclear factor erythroid-2 related factor 2 inhibits human disc nucleus pulpous cells apoptosis induced by excessive hydrogen peroxide
RESUMO OBJETIVO O fator 2 relacionado a NF-E2 (Nrf2)/elemento de resposta antioxidante (ARE) é uma nova via defensiva envolvida no estresse oxidativo e químico das células. O objetivo deste estudo foi explorar o papel do Nrf2 na apoptose das células do núcleo pulposo do disco humano induzida pelo peróxido de hidrogênio (H2O2). MÉTODOS O modelo de
Rev. Assoc. Med. Bras.. Publicado em: 2020-07
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3. Retraction notice for: “Ginsenoside Rd inhibits IL-1β-induced inflammation and degradation of intervertebral disc chondrocytes by increasing IL1RAP ubiquitination” [Braz J Med Biol Res (2019) 52(9): e8525]
Braz J Med Biol Res. Publicado em: 05/12/2019
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4. SYMPTOMATIC INTRADISCAL VACUUM PHENOMENON
RESUMO Objetivo: O fenômeno do vácuo intervertebral (FVI) é um achado comum no estudo da doença degenerativa do disco. A dor lombar discogênica pode se manifestar de diferentes formas, incluindo a irradiação para os membros inferiores. O presente estudo pretende reconhecer os estudos complementares utilizados para diagnosticar o FVI, determinar sua s
Coluna/Columna. Publicado em: 14/11/2019
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5. Inflammatory biomarkers in sera of patients with intervertebral disc degeneration
RESUMO Objetivo: Avaliar os níveis de fatores inflamatórios nos discos intervertebrais (interleucina 6) e proteinase (catepsina B) em pacientes com doença degenerativa de disco intervertebral, além de verificar os níveis séricos de interleucina 6, ácido hialurônico e atividade sérica da catepsina B. Métodos: Foi realizado exame imuno-histoquímic
Einstein (São Paulo). Publicado em: 29/08/2019
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6. [RETRACTED ARTICLE] Ginsenoside Rd inhibits IL-1β-induced inflammation and degradation of intervertebral disc chondrocytes by increasing IL1RAP ubiquitination
Many compounds of ginsenosides show anti-inflammatory properties. However, their anti-inflammatory effects in intervertebral chondrocytes in the presence of inflammatory factors have never been shown. Increased levels of pro-inflammatory cytokines are generally associated with the degradation and death of chondrocytes; therefore, finding an effective and non
Braz J Med Biol Res. Publicado em: 12/08/2019
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7. X-ray dynamic observation of cervical degenerative disease induced by unbalanced dynamic and static forces in rats
Abstract Purpose: To investigate dynamically the X-ray appearance of cervical degenerative disease induced by unbalanced dynamic and static forces in rats. Methods: A total of 60 Sprague Dawley rats were randomized into test (n=45) and control (n=15) groups, which were randomly subdivided into the one-, three- and six-month post-operative groups. The tes
Acta Cir. Bras.. Publicado em: 2017-09
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8. CORRELAÇÃO CLÍNICO-RADIOLÓGICA DAS ALTERAÇÕES DEGENERATIVAS DA COLUNA - REVISÃO SISTEMÁTICA
RESUMO Revisão sistemática da literatura de avaliação por imagem das alterações degenerativas da coluna e sua correlação clínica. A revisão sistemática da literatura foi realizada e seus resultados, avaliados com relação à presença de correlação clínica, assim como o tipo de método de imagem utilizado. Os termos de pesquisa foram "Interver
Coluna/Columna. Publicado em: 2016-12
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9. Surgical treatment of Denis type B thoracolumbar burst fracture with neurological deficiency by paraspinal approach
We aimed to describe the surgical technique and clinical outcomes of paraspinal-approach reduction and fixation (PARF) in a group of patients with Denis type B thoracolumbar burst fracture (TLBF) with neurological deficiencies. A total of 62 patients with Denis B TLBF with neurological deficiencies were included in this study between January 2009 and Decembe
Braz J Med Biol Res. Publicado em: 03/11/2016
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10. A retrospective study evaluating the correlation between the severity of intervertebral disc injury and the anteroposterior type of thoracolumbar vertebral fractures
OBJECTIVE: To evaluate the correlation between the severity of intervertebral disc injury and the anteroposterior type of thoracolumbar vertebral fractures. METHODS: Fifty-six cases of thoracolumbar vertebral fractures treated in our trauma center from October 2012 to October 2013 were included in this study. The fractures were classified by the anteropost
Clinics. Publicado em: 2016-06
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11. Effect of microRNA-21 on the proliferation of human degenerated nucleus pulposus by targeting programmed cell death 4
This study aims to explore the effect of microRNA-21 (miR-21) on the proliferation of human degenerated nucleus pulposus (NP) by targeting programmed cell death 4 (PDCD4) tumor suppressor. NP tissues were collected from 20 intervertebral disc degeneration (IDD) patients, and from 5 patients with traumatic spine fracture. MiR-21 expressions were tested. NP ce
Braz J Med Biol Res. Publicado em: 24/05/2016
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12. STUDIES OF MOLECULAR CHANGES IN INTERVERTEBRAL DISC DEGENERATION IN ANIMAL MODEL
ABSTRACT Objective: To evaluate the structural and molecular changes in the extracellular matrix (ECM) during the process of intervertebral disc degeneration, using animal model. Methods: Wistar rats underwent intervertebral disc degeneration through 20-gauge needle puncture, and 360° rotation applied for 30 sec, representing the degenerated group, whil
Acta ortop. bras.. Publicado em: 2016-02