Iron Protoporphyrin Ix
Mostrando 1-12 de 48 artigos, teses e dissertações.
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1. Análise de uma heme oxigenase funcional em Trypanosoma cruzi / Heme oxygenase analysis in Trypanosoma cruzi
Trypanosoma cruzi, the ethiologic agent of Chagas disease, is transmitted through triatomine vectors during their blood-meal on vertebrate host. These hematophagous insects ingest blood about 6 to 12 times its original weight, reaching in a single meal about 10 mM heme bound to hemoglobin. Heme (iron protoporphyrin IX) is an important molecule in metabolism
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/02/2011
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2. AMPEROMETRIC SENSOR BASE OF AN IMPRESSION OF POLYMER MOLECULAR PROTOPORPHYRIN IX WITH IRON FOR THE DETERMINATION OF 4-AMINOPHENOL / SENSOR AMPEROMÉTRICO A BASE DE UM POLÍMERO DE IMPRESSÃO MOLECULAR COM PROTOPORFIRINA IX DE FERRO PARA A DETERMINAÇÃO DE 4-AMINOFENOL
This work presents an analytical study on determination of 4-aminophenol (4-APh) with a system based on molecurlaly imprinted polymer (MIP) and iron protoporphyrin IX as biomimetic sensor of the peroxidase enzyme. The MIP synthesis was performed by the precipitation method and the analytical determinations by amperometric measurements with a glassy carbon el
Publicado em: 2010
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3. ESTUDOS COMPUTACIONAIS DA INTERAÇÃO DE PORFIRINAS E SEUS COMPLEXOS DE FERRO COM ALBUMINA SÉRICA HUMANA / COMPUTATIONAL STUDIES OF THE INTERACTION OF PORPHYRINS AND THEIR IRON COMPLEXES WITH HUMAN SERUM ALBUMIN
The uprising of HIV and other viruses in the beginning of the 80s, as well as the expansion of other diseases like hepatitis C has stimulated research in order to develop blood substitutes. Research based on modified Human Serum Albumin associated with heme has shown a promissory line in this direction. In the present work we make a computational study about
Publicado em: 2008
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4. Papel do HEME (Ferro protoporfirina IX) na Resposta Inflamatória: mecanismos moleculares envolvidos no recrutamento de neutrófilos
Heme (Iron Protoporphyrin IX), a ubiquitous molecule present in organisms of all kingdoms, is composed of an atom of iron linked to the four ligand groups of porphyrin. As a prosthetic moiety on inactive apo-heme proteins, heme provides a wide range of biological functions determined in part by the polypeptide associated to it. Diseases of increased hemolysi
Publicado em: 2005
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5. Effects of Iron and Oxygen on Chlorophyll Biosynthesis 1: I. IN VIVO OBSERVATIONS ON IRON AND OXYGEN-DEFICIENT PLANTS
Corn (Zea mays, L.), bean (Phaseolus vulgaris L.), barley (Hordeum vulgare L.), spinach (Spinacia oleracea L.), and sugarbeet (Beta vulgaris L.) grown under iron deficiency, and Potamogeton pectinatus L, and Potamogeton nodosus Poir. grown under oxygen deficiency, contained less chlorophyll than the controls, but accumulated Mg-protoporphyrin IX and/or Mg-pr
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6. Activation of purified soluble guanylate cyclase by protoporphyrin IX.
Soluble guanylate cyclase [GTP pyrophosphate-lyase (cyclizing), EC 4.6.1.2] purified from bovine lung is markedly activated (30- to 40-fold) by protoporphyrin IX (Ka, 15-25 nM) and is inhibited by hematin (Ki, 3.7 microM) when MgGTP is used as substrate. Guanylate cyclase possesses specific activities (mumol of cGMP per min/mg of protein) of 0.1-0.2 (MgGTP)
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7. Effects of Iron and Oxygen on Chlorophyll Biosynthesis 1: II. OBSERVATIONS ON THE BIOSYNTHETIC PATHWAY IN ISOLATED ETIOCHLOROPLASTS
The conversion of l-glutamate to δ-aminolevulinate, in preparations of cucumber etiochloroplasts incubated in vitro, was inhibited by protoheme IX and Mg-protoporphyrin IX. Mg-protoporphyrin IX was destroyed in the presence of air and plastids; this breakdown was accelerated by S-adenosyl methionine. Mg-protoporphyrin IX was also converted to protochlorophy
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8. Detection of Heme-Binding Proteins in Epidemic Strains of Burkholderia cepacia
A panel of 30 previously characterized strains representing five genomovars from the Burkholderia cepacia complex (E. Mahenthiralingam, T. Coenye, J. W. Chung, D. P. Speert, J. R. W. Govan, P. Taylor, and P. Vandamme, J. Clin. Microbiol. 38:910–913, 2000) were examined for their iron protoporphyrin IX-binding ability. These included B. cepacia genomovars I
American Society for Microbiology.
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9. Studies in porphyria: functional evidence for a partial deficiency of ferrochelatase activity in mitogen-stimulated lymphocytes from patients with erythropoietic protoporphyria.
In this paper we show that the ferrochelatase defect in erythropoietic protoporphyria (EPP) can readily be identified in mitogen-stimulated lymphocytes since such cells from patients with EPP accumulate approximately twice as much protoporphyrin IX as cells from normal subjects when incubated with a porphyrin precursor, gamma-aminolevulinic acid (ALA). Treat
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10. Modulation of ferritin H-chain expression in Friend erythroleukemia cells: transcriptional and translational regulation by hemin.
The mechanisms that regulate the expression of the H chain of the iron storage protein ferritin in Friend erythroleukemia cells (FLCs) after exposure to hemin (ferric protoporphyrin IX), protoporphyrin IX, and ferric ammonium citrate (FAC) have been investigated. Administration of hemin increases the steady-state level of ferritin mRNA about 10-fold and that
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11. HEMATIN-REQUIRING PLASMODIAL MYXOMYCETE
Daniel, John W. (University of Wisconsin, Madison), Jacqueline Kelley, and Harold P. Rusch. Hematin-requiring plasmodial myxomycete. J. Bacteriol. 84:1104–1110. 1962.—The myxomycete Physarum polycephalum, previously shown to require chick embryo extract for growth on a partially defined, soluble medium, grows as well if hematin or certain hemoproteins ar
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12. Induction of δ-Aminolevulinic Acid Synthase Activity and Inhibition of Heme Synthesis in Euglena gracilis by N-Methyl Mesoporphyrin IX 1
N-Methyl mesoporphyrin IX, an inhibitor of heme synthesis, increases extractable δ-aminolevulinic acid (ALA) synthase activity when administered to growing cultures of Euglena gracilis Klebs strain Z Pringsheim in micromolar concentrations. Wild-type light-grown green cells and white aplastidic cells exhibited 2.8-fold and 1.8-fold increases, respectively,