Lectin I
Mostrando 1-12 de 305 artigos, teses e dissertações.
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1. Inhibitory effect of Lonchocarpus araripensis lectin in rat acute models of inflammation
Abstract: Dalbergieae tribe lectins, possessing binding affinity for galactose and mannose, present inflammatory and nociceptive effects, while those for N-acetylglucosamine are anti-inflammatory. Since the anti-inflammatory effect of the seed lectin of L. araripensis (LAL) had been already demonstrated in mice, this effect was presently evaluated in rat mod
An. Acad. Bras. Ciênc.. Publicado em: 19/06/2019
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2. Complement system contributes to modulate the infectivity of susceptible TcI strains of Trypanosoma cruzi
BACKGROUND Trypanosoma cruzi is a protozoan parasite and an etiological agent of Chagas disease. There is a wide variability in the clinical outcome of its infection, ranging from asymptomatic individuals to those with chronic fatal mega syndromes. Both parasite and host factors, as well as their interplay, are thought to be involved in the process. OBJECT
Mem. Inst. Oswaldo Cruz. Publicado em: 19/02/2018
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3. Mannose-binding lectin 2 (Mbl2) gene polymorphisms are related to protein plasma levels, but not to heart disease and infection by Chlamydia
The presence of the single nucleotide polymorphisms in exon 1 of the mannose-binding lectin 2 (MBL2) gene was evaluated in a sample of 159 patients undergoing coronary artery bypass surgery (71 patients undergoing valve replacement surgery and 300 control subjects) to investigate a possible association between polymorphisms and heart disease with Chlamydia i
Braz J Med Biol Res. Publicado em: 12/12/2016
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4. Evaluation of the cytokine mannose-binding lectin as a mediator of periportal fibrosis progression in patients with schistosomiasis
INTRODUCTION : We hypothesized higher mannose-binding lectin level and classic factors (i.e., age, sex, alcohol consumption, exposure, and specific treatment) are associated with the severity of periportal fibrosis in schistosomiasis. METHODS : This cross-sectional study involved 79 patients infected with Schistosoma mansoni with severe or mild/moderate per
Rev. Soc. Bras. Med. Trop.. Publicado em: 2015-06
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5. Magnetic Parkia pendula seed gum as matrix for Concanavalin A lectin immobilization and its application in affinity purification
O presente trabalho objetivou magnetizar a goma de sementes de Parkia pendula e demonstrar seu uso como matriz para imobilização covalente da lectina Concanavalina A. O composto foi aplicado em purificação de glicoconjugados por afinidade. Sementes de Parkia pendula foram hidratadas e a goma do sobrenadante foi precipitada, lavada com etanol e seca. A go
An. Acad. Bras. Ciênc.. Publicado em: 15/08/2014
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6. Analysis of castor bean ribosome-inactivating proteins and their gene expression during seed development
Ribosome-inactivating proteins (RIPs) are enzymes that inhibit protein synthesis after depurination of a specific adenine in rRNA. The RIP family members are classified as type I RIPs that contain an RNA-N-glycosidase domain and type II RIPs that contain a lectin domain (B chain) in addition to the glycosidase domain (A chain). In this work, we identified 30
Genet. Mol. Biol.. Publicado em: 18/01/2013
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7. Physicochemical Characterization and the Effect on Oral Bacteria Strains of a seed lectin from Andira surinamensis (BONDT) SPLITG. ex AMSHOFF / CaracterizaÃÃo fÃsico-quÃmica e efeito sobre bactÃrias orais de uma lectina de sementes de Andira surinamensis (Bondt) Splitg. ex Amshoff.
As sementes de Andira surinamensis (Bondt) Splitg. ex Amshoff, uma espÃcie pertencente à famÃlia Leguminosae, subfamÃlia Papilionoideae, tribo Dalbergieae, possuem uma lectina glicose/manose especÃfica, que aglutina eritrÃcitos de coelhos nativos ou tratados com enzimas proteolÃticas. A lectina de sementes de Andira surinamensis foi purificada atravÃ
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/02/2012
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8. Efeitos da Lectina da Alga Marinha Vermelha Solieria filiformis (KÃtzing) P.W. Gabrielson na NocicepÃÃo e InflamaÃÃo em Animais / Effects of the Lectin from the Red Marine Alga Solieria filiformis (KÃtzing) P.W. Gabrielson in Nociception and Inflammation in Animals
As algas marinhas sÃo fontes de compostos bioativos, os quais vÃm despertando interesse em aplicaÃÃes farmacolÃgicas. Dentre esses, destacam-se as lectinas, que sÃo (glico)proteÃnas que se ligam a mono ou oligossacarÃdeos especÃficos. O objetivo desse trabalho foi isolar a lectina da alga marinha vermelha Solieria filiformis (LSf), investigar as sua
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/02/2012
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9. Estudo das atividades das cabenegrinas A-I e A-II frente aos efeitos hematolÃgicos e histolÃgicos induzidos pelo veneno total e fraÃÃes da serpente Bothrops neuwiedi em camundongos Swiss. / Study of the activities of cabenegrinas A-I and A-II compared to the histological and hematological effects induced by the venom and fractions of the snake Bothrops neuwiedi in Swiss mice.
The venom of the Bothrops neuwiedi provokes an action mainly of the hemorrhagic, proteolytic and coagulant type. When inoculated, the venom cause primarily a local action, and secondarily a systemic action. The systemic effects of poisoning include changes in various systems such as hematological, cardiovascular, liver, urinary, respiratory, immune, digestiv
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/06/2011
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10. Transformação genética em macieira, com o gene bvlI. / Transformação genética em macieira, com o gene bvlI. / Genetic transformation in apple, with gene bvlI / Genetic transformation in apple, with gene bvlI
O objetivo principal do presente trabalho foi introduzir o gene bvlI com potencial antifúngíco confirmado da lectina de Bauhinia variegata, em macieira (Malus domestica Borkh), cv. Gala, para estabelecer resistência ao fungo Coletotrichum gloeosporioides, causador da Mancha Foliar. Foram realizados experimentos de multiplicação in vitro, regeneração d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/06/2011
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11. ResoluÃÃo da estrutura tridimensional da lectina de Dioclea violacea Mart para estudo da relaÃÃo estrutura-funÃÃo / Three-dimensional structure of lectin from Dioclea violacea for study structure/function relation
As lectinas da subtribo Diocleinae pertencem à famÃlia de Leguminosas e sÃo caracterizadas pela alta homologia entre suas sequÃncias de aminoÃcidos. Apesar da alta similaridade estrutural o mesmo nÃo acontece nas atividades biolÃgicas das lectinas dessa famÃlia. Estudos mostram que a modificaÃÃo de poucos aminoÃcidos em suas sequÃncias à capaz d
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2011
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12. Evaluation of the antischistosomal activity of sulfated α-D-glucan from the lichen Ramalina celastri free and encapsulated into liposomes
The antischistosomal activity of the sulfated polysaccharide α-D-glucan (Glu.SO4) extracted from Ramalina celastri was evaluated after encapsulation into liposomes (Glu.SO4-LIPO) in Schistosoma mansoni-infected mice. The effect of treatment with Glu.SO4 and Glu.SO4-LIPO (10 mg/kg) on egg elimination, worm burden and hepatic granuloma formation was assessed
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-04