Leishmania Mexicana
Mostrando 1-12 de 128 artigos, teses e dissertações.
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1. Development of Leishmania mexicana in Lutzomyia longipalpis in the absence of sugar feeding
The leishmaniases are caused by Leishmania parasites and transmitted through the bites of phlebotomine sand flies. During parasite development inside the vector’s midgut, promastigotes move towards the stomodeal valve, a mechanism that is crucial for transmission. It has been reported that the sugar meal acquired by sand flies during feeding between bloodm
Mem. Inst. Oswaldo Cruz. Publicado em: 20/05/2019
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2. Molecular typing reveals the co-existence of two transmission cycles of American cutaneous leishmaniasis in the Andean Region of Venezuela with Lutzomyia migonei as the vector
BACKGROUND The transmission routes for American cutaneous leishmaniasis (ACL) are in flux, so studies examining its transmission in humans, mammalian hosts, and sand fly vectors are urgently needed. OBJECTIVES The aim of this work was understand the epidemiological cycles of Leishmania spp., which causes ACL in the Andean Region of Venezuela, by identifying
Mem. Inst. Oswaldo Cruz. Publicado em: 06/12/2018
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3. Genetic evidence of enzootic leishmaniasis in a stray canine and Texas mouse from sites in west and central Texas
We detected Leishmania mexicana in skin biopsies taken from a stray canine (Canis familiaris) and Texas mouse (Peromyscus attwateri) at two ecologically disparate sites in west and central Texas using polymerase chain reaction (PCR). A single PCR-positive dog was identified from a sample of 96 stray canines and was collected in a peri-urban area in El Paso C
Mem. Inst. Oswaldo Cruz. Publicado em: 2016-10
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4. Field validation of a Leishmania (Leishmania) mexicana exo-antigens ELISA for diagnosing tegumentary leishmaniasis in regions of Leishmania (Viannia) predominance
Background: Several tests are performed to obtain better accuracy when diagnosing American tegumentary leishmaniasis (ATL). It is believed that antigens released via secretion, excretion and metabolism are more specific than are antigens released by the lysis of Leishmaniaparasites. Such antigens are known as exo-antigens (exo-Ag) and are formed from product
Braz J Infect Dis. Publicado em: 2015-06
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5. Nitric oxide production by Peromyscus yucatanicus (Rodentia) infected with Leishmania (Leishmania) mexicana
Peromyscus yucatanicus (Rodentia: Cricetidae) is a primary reservoir of Leishmania (Leishmania) mexicana (Kinetoplastida: Trypanosomatidae). Nitric oxide (NO) generally plays a crucial role in the containment and elimination of Leishmania. The aim of this study was to determine the amount of NO produced by P. yucatanicus infected with L. (L.) mexicana. Subcl
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-04
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6. Regulatory volume decrease in Leishmania mexicana: effect of anti-microtubule drugs
The trypanosomatid cytoskeleton is responsible for the parasite's shape and it is modulated throughout the different stages of the parasite's life cycle. When parasites are exposed to media with reduced osmolarity, they initially swell, but subsequently undergo compensatory shrinking referred to as regulatory volume decrease (RVD). We studied the effects of
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-02
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7. Preliminary study towards a novel experimental model to study localized cutaneous leishmaniasis caused bY Leishmania (Leishmania) mexicana
There is not an experimental model of localized cutaneous leishmaniasis (LCL) caused by Leishmania (Leishmania) mexicana. The aim of the present study was to characterize the clinical and histological features of Peromyscus yucatanicus experimentally infected with L. (L.) mexicana. A total of 54 P. yucatanicus (groups of 18) were inoculated with 1x10(6) prom
Revista do Instituto de Medicina Tropical de São Paulo. Publicado em: 2012-06
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8. Fusão Homotípica e Heterotípica entre Vacúolos Parasitóforos de Leishmania spp / Homotypic and Heterotypic Fusion between Leishmania spp. Parasitophorous Vacuoles
Most non-viral intracellular pathogens gain entrance into human and animal host cells by classic or modifIed phagocytosis and are thus lodged in phagosomes which they may or not continue to occupy in the course of infection. Their survival and multiplication within host cells depend on modulation of the compositional and functional phenotypes of the phagosom
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/02/2011
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9. Chemistry, cytotoxicity and antileishmanial activity of the essential oil from Piper auritum
Leishmaniasis is one of the most important parasitic infections, but current treatments are unsatisfactory due to their toxicity, cost and resistance. Therefore, the development of new antileishmanial compounds is imperative. Many people who live in endemic areas use plants as an alternative to treat the disease. In this paper, we characterised the essential
Memórias do Instituto Oswaldo Cruz. Publicado em: 2010-03
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10. Molecular and biochemical characterisation of Trypanosoma cruzi phosphofructokinase
The characterisation of the gene encoding Trypanosoma cruzi CL Brener phosphofructokinase (PFK) and the biochemical properties of the expressed enzyme are reported here. In contradiction with previous reports, the PFK genes of CL Brener and YBM strain T. cruzi were found to be similar to their Leishmania mexicana and Trypanosoma brucei homologs in terms of b
Memórias do Instituto Oswaldo Cruz. Publicado em: 2009-08
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11. Comparison of small mammal prevalence of Leishmania (Leishmania) mexicana in five foci of cutaneous leishmaniasis in the State of Campeche, Mexico
In the Yucatan Peninsula of Mexico, 95% of the human cases of Cutaneous Leishmaniasis are caused by Leishmania (Leishmania) mexicana with an incidence rate of 5.08 per 100,000 inhabitants. Transmission is limited to the winter months (November to March). One study on wild rodents has incriminated Ototylomys phyllotis and Peromyscus yucatanicus as primary res
Revista do Instituto de Medicina Tropical de São Paulo. Publicado em: 2009-04
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12. Palladium polypyridyl complexes: synthesis, characterization, DNA interaction and biological activity on Leishmania (L.) mexicana
Este trabalho descreve a busca de novos agentes com potencial quimioterápico baseados em complexos de metais de transição com ligantes planares. Neste estudo, complexos polipiridilpaládio foram sintetizados e caracterizados por análise elementar e por espectroscopias de RMN e de absorção no UV-visível e no infravermelho. A interação dos complexos c
J. Braz. Chem. Soc.. Publicado em: 2008