Leishmanicidal And Trypanocidal Evaluation
Mostrando 1-4 de 4 artigos, teses e dissertações.
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1. Isolation and characterization of sesquiterpene lactones from Calea uniflora Less. and their leishmanicidal and trypanocidal activities
Calea uniflora Less., commonly known in Brazil as “erva-de-lagarto” and “arnica-da-praia”, is used in folk medicine to treat internal and external bruises and as anti-inflammatory. However, despite the popular use there is a lack of information in terms of isolation and biological evaluation of its secondary metabolites. Thus, the aims of this study
Quím. Nova. Publicado em: 2021-06
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2. A New Furanoheliangolide Sesquiterpene Lactone from Calea pinnatifida (R. Br.) Less. (Asteraceae) and Evaluation of Its Trypanocidal and Leishmanicidal Activities
Calea pinnatifida (R. Br.) Less. is commonly known in Brazil as "cipó-cruz", "quebra-tudo" or "aruca". This species is employed in folk medicine as giardicidal, amoebicidal and to treat digestive disorders. The present paper describes the isolation and structure determination of a new furanoheliangolide sesquiterpene lactone named 11,13-dihydroxy-calaxin, i
J. Braz. Chem. Soc.. Publicado em: 2017-02
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3. Evaluation of leishmanicidal effect in derivatives of dibenzylbutirolactonic lignans. / Avaliação do efeito leishmanicida de derivados de lignanas dibenzilbutirolactônicas
Leishmaniasis is an infection caused by a protozoan parasite of the genus Leishmania, being the second great incidence of parasitic diseases in the world. In the search for new drugs or substances with low costs and low toxicity wich could be used in case of infection and situations of parasite resistance, being evaluated the possibility to use natural or sy
Publicado em: 2009
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4. Síntese e avaliação do potencial leishmanicida e tripanocida de 1,6-naftiridinas substituídas
The trypanosomiasis and the leishmaniasis are serious problems of public health affecting millions of people in the country and worldwide. The majority of the drugs used in the treatment of these diseases was developed many decades ago, and present little efficacy and intense collateral effects. The biologycal importance of the naphthyridines and the interes
Publicado em: 2006