Leptin Receptor
Mostrando 1-12 de 136 artigos, teses e dissertações.
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1. Investigation of maternal polymorphisms in genes related to glucose homeostasis and the influence on birth weight: a cohort study
Abstract Objectives: To contribute to a better understanding of the maternal genetic mechanisms that influence obstetric outcomes and that are involved in maternal and child health, this study aimed to evaluate the association between maternal genetic variants and the offspring birth weight by analyzing single-nucleotide polymorphisms (SNPs) in genes relate
Jornal de Pediatria. Publicado em: 2022
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2. Effect of Feed Restriction and Photoperiod on Reproduction and LEPR, MELR mRNA Expression of Layers
ABSTRACT Photoperiod and nutrition are major factors that affect the reproductive efficiency particularly in female animals. In this study we examined the interaction of photoperiod and food restriction on growth, sexual maturation and receptor mRNA expressions of leptin, melatonin, and estrogen in abdominal fat and the ovary of pullets. There were no intera
Braz. J. Poult. Sci.. Publicado em: 11/11/2019
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3. Adipokine gene variability and plasma levels in patients with chronic periodontitis -a case-control study
Abstract: Specific variants in genes that encode adipokines and their mRNA and protein expression were previously studied in type 2 diabetes mellitus (T2DM) and obesity, and similar studies have been performed for chronic periodontitis (CP). The aim of this case–control study was to investigate the possible impacts of adiponectin (ADIPOQ), leptin (LEP) and
Braz. oral res.. Publicado em: 25/04/2019
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4. ADRB2 Gln27Glu polymorphism influenced changes in leptin but not body composition or metabolic and other inflammatory parameters after twelve weeks of combined training in overweight adolescents
ABSTRACT Aim To compare the anthropometric, metabolic, and inflammatory parameters of overweight adolescents after 12-weeks of resistance and aerobic training (CT), taking into account the Gln27Glu polymorphism of the β2 adrenergic receptor (ADRB2) gene. Methods Forty-seven adolescents (15.05±1.07y) were assigned to one of four groups, according to the p
Motriz: rev. educ. fis.. Publicado em: 15/01/2018
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5. Type 2 diabetes-associated genetic variants of FTO, LEPR, PPARg, and TCF7L2 in gestational diabetes in a Brazilian population
ABSTRACT Objective Gestational diabetes mellitus (GDM) is a metabolic disorder that shares pathophysiologic features with type 2 diabetes mellitus. The aim of this study was to investigate the association of the polymorphisms fat mass and obesity-associated (FTO) rs1421085, leptin receptor (LEPR) rs1137100, rs1137101, peroxisome proliferator-activated rece
Arch. Endocrinol. Metab.. Publicado em: 27/03/2017
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6. Metabolic syndrome and related variables, insulin resistance, leptin levels, and PPAR-γ2 and leptin gene polymorphisms in a pedigree of subjects with bipolar disorder
Objective:Evidence points to a high prevalence of metabolic dysfunction in bipolar disorder (BD), but few studies have evaluated the relatives of subjects with BD. We conducted a cross-sectional study in an extended family of patients with BD type I.Methods:The available relatives of the same family were interviewed (DSM-IV-R) and assessed in fasting conditi
Rev. Bras. Psiquiatr.. Publicado em: 13/02/2015
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7. The testis of the mice C57/BL6 offspring in adulthood have alterations due to maternal caffeine consumption
PURPOSE: To investigate the effects of the maternal caffeine consumption during pregnancy to adult male testis mice offspring. METHODS: Twenty pregnant mice were divided into control group (c) and caffeine group (cf). dams received daily saline or 20 mg/kg of caffeine subcutaneously. Male offspring were monitored daily until 13th week. The testis were
Acta Cir. Bras.. Publicado em: 2014-01
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8. Leptin and leptin receptor expressions in prostate tumors may predict disease aggressiveness?
PURPOSE: The aim of this study was to evaluate the expression of leptin and its receptor in histological sections of prostate tumors, and their association with prognostic factors. METHODS: A total of 532 surgical specimens from prostate cancer were studied. After histopathological diagnosis, the samples were included in tissue microarrays containing cores
Acta Cir. Bras.. Publicado em: 2014
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9. Leptin receptor (Ob-R) mRNA expression and serum leptin concentration in patients with colorectal and metastatic colorectal cancer
The objective of the present study was to investigate the effect of leptin on the progression of colorectal carcinoma to metastatic disease by analyzing the serum leptin concentration and Ob-R gene expression in colon cancer tissues. Tissue samples were obtained from 31 patients who underwent surgical resection for colon (18 cases) and metastatic colon (13 c
Braz J Med Biol Res. Publicado em: 19/03/2013
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10. Expression levels of candidate genes for intramuscular fat deposition in two Banna mini-pig inbred lines divergently selected for fatness traits
Intramuscular fat (IMF) content plays an important role in meat quality. Many genes involved in lipid and energy metabolism were identified as candidate genes for IMF deposition, since genetic polymorphisms within these genes were associated with IMF content. However, there is less information on the expression levels of these genes in the muscle tissue. Thi
Genet. Mol. Biol.. Publicado em: 13/11/2012
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11. Leptina em fêmeas suínas: relação com status reprodutivo e causas de descarte / Leptina em fêmeas suínas: relação com status reprodutivo e causas de descarte / Leptin in swine females: relationship between reproductive status and culling causes / Leptin in swine females: relationship between reproductive status and culling causes
A leptina é um hormônio peptídico multifuncional, produzido primariamente pelo tecido adiposo, com receptores (Ob-Rs) presentes em órgãos reprodutivos, hipotálamo e hipófise, que atua na regulação do apetite e no gasto energético, com potencial influência sobre a expressão da função reprodutiva, na puberdade e após a lactação. Desordens repr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/11/2011
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12. Glutamato participa do controle hipotalâmico da homeostase energética em ratos / Glutamate participate of hypothalamic control of energetic homeostasis in rats
O receptor ionotrópico NMDA (N-metil-D-aspartato) é um receptor de glutamato envolvido em uma série de processos essenciais para o funcionamento adequado do sistema nervoso central. A ativação ou expressão anômala deste receptor pode contribuir para o desenvolvimento de doenças como Parkinson e Alzheimer. Um estudo utilizando um microarranjo de DNA r
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/07/2011