Leukaemia
Mostrando 1-12 de 678 artigos, teses e dissertações.
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1. Diffuse bone marrow metastases of small cell carcinoma with associated erythrophagocytosis mimicking acute leukaemia
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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2. Prolonged response to recombinant human erythropoietin treatment in patients with myelodysplastic syndrome at a single referral centre in Brazil
OBJECTIVES: To evaluate the effects of epoetin (EPO) alfa treatment on overall survival, event-free survival and response duration in patients with myelodysplastic syndrome (MDS) who were treated at a haematological referral centre in northeastern Brazil. METHODS: This was a retrospective cohort study of 36 patients diagnosed with MDS and treated with EPO
Clinics. Publicado em: 09/09/2019
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3. Identification of neprilysin as a potential target of arteannuin using computational drug repositioning
ABSTRACT The discovery of arteannuin (qinghaosu) in the 20th Century was a major advance for medicine. Besides functioning as a malaria therapy, arteannuin is a pharmacological agent in a range of other diseases, but its mechanism of action remains obscure. In this study, the reverse docking server PharmMapper was used to identify potential targets of artean
Braz. J. Pharm. Sci.. Publicado em: 22/06/2017
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4. Thyroid nodule: first manifestation of chronic lymphocytic leukaemia
The presence of chronic lymphocytic leukaemia (CLL) cells in the thyroid gland is most likely due to a secondary involvement by a systemic disease. The reported incidence of CLL involving the thyroid is extremely low, representing about 3–4% of all thyroid lymphoproliferative neoplasm. We report a rare case of CLL presenting initially in the thyroid gland.
Arch. Endocrinol. Metab.. Publicado em: 2015-04
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5. Inferences about the global scenario of human T-cell lymphotropic virus type 1 infection using data mining of viral sequences
Human T-cell lymphotropic virus type 1 (HTLV-1) is mainly associated with two diseases: tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP/HAM) and adult T-cell leukaemia/lymphoma. This retrovirus infects five-10 million individuals throughout the world. Previously, we developed a database that annotates sequence data from GenBank and the present
Mem. Inst. Oswaldo Cruz. Publicado em: 23/05/2014
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6. Imatinib activity on Schistosoma mansoni
Imatinib, a drug used for treatment of human chronic myeloid leukaemia, due to its activity against protein kinases, has been also evaluated in vitro against Schistosoma mansoni showing high schistosomicidal activity. In the present experiments imatinib activity in vitro was confirmed at the doses of 25 µM, 50 µM and 100 µM. The first drug activity observ
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-11
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7. Upregulation of hsa-miR-125b in HTLV-1 asymptomatic carriers and HTLV-1-associated myelopathy/tropical spastic paraparesis patients
The retrovirus human T lymphotropic virus type 1 (HTLV-1) promotes spastic paraparesis, adult T cell leukaemia and other diseases. Recently, some human microRNAs (miRNAs) have been described as important factors in host-virus interactions. This study compared miRNA expression in control individuals, asymptomatic HTLV-1 carriers and HTLV-1 associated myelopat
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-09
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8. Immunity against hepatitis B and measles vaccination after chemotherapy for acute lymphoblastic leukaemia in children: revaccination policy
Rev. Bras. Hematol. Hemoter.. Publicado em: 2012
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9. Investigação do funcionamento cognitivo de pacientes pediátricos diagnosticados com leucemia linfóide aguda - LLA
O presente trabalho investigou o funcionamento cognitivo de crianças diagnosticadas com Leucemia Linfóide Aguda (LLA) acompanhadas por instituições oncológicas pediátricas no município de Natal/RN. Participaram deste estudo 20 crianças diagnosticadas com LLA, de ambos os sexos, com idades entre seis e doze anos, que estavam em tratamento (n=10) e for
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/04/2011
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10. Chemical composition and antiproliferative activity of essential oil from aerial parts of a medicinal herb Artemisia herba-alba
Artemisia herba-alba Asso., Asteraceae, is widely used in Morrocan folk medicine for the treatment of different health disorders. However, no scientific or medical studies were carried out to assess the cytotoxicity of A. herba-alba essential oil against cancer cell lines. In this study, eighteen volatile compounds were identified by GC-MS analysis of the es
Revista Brasileira de Farmacognosia. Publicado em: 24/06/2011
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11. Active caspase-3 detection to evaluate apoptosis induced by Verbena officinalis essential oil and citral in chronic lymphocytic leukaemia cells
Verbena officinalis L., Verbenaceae, commonly known as vervain, is a plant widely used in medicine. Despite of its widespread use in different traditional practices, the mechanisms of pharmacological actions of the plant and its volatile oil are still unclear. We evaluated the pro-apoptotic activity of V. officinalis essential oil and of its main component,
Revista Brasileira de Farmacognosia. Publicado em: 20/05/2011
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12. Estudo dos ligantes da proteína prion celular com ênfase em estress inducible protein 1: modificação pós-traducional, tráfego e sinalização
A proteina prion celular (PrPC) constitui uma plataforma na membrana plasmatica capaz de interagir com diversos ligantes mediando a reuniao de complexos de sinalizacao na superficie celular. Um dos ligantes mais bem descritos para PrPC e a co-chaperonina Stress Inducible Protein1 ou STI1. STI1 e secretada por astrocitos e interage com PrPC na superficie neur
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/09/2010