Leukomalacia
Mostrando 1-12 de 12 artigos, teses e dissertações.
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1. Prevalence of metabolic syndrome-like in the follow-up of very low birth weight preterm infants and associated factors
Resumo Objetivo: Avaliar a prevalência de síndrome metabólica "like" em população de crianças prematuras com muito baixo peso de nascimento (< 1500 gramas) aos dois anos de idade corrigida e identificar a ocorrência de fatores de risco associados. Métodos: Estudo transversal que incluiu prematuros nascidos durante um período de cinco anos com muit
J. Pediatr. (Rio J.). Publicado em: 01/07/2019
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2. Aplicação clínica da ultra-sonografia craniana com doppler em crianças prematuras de muito baixo peso
Transcranial Doppler sonography is the technique more designate to detect intracranial hemorrhage (ICH) and periventricular leukomalacia (PVL) among preterm. This technique evidence the most important cerebral arteries, mainly arteries the circle of Willis, obtaining blood flow arteries resistance index (RI), becoming upset in cranial hemorrhage and hypoxic-
Publicado em: 2010
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3. Imagem por tensores de difusão em crianças com leucomalácia periventricular / Diffusion tensor imaging in children with periventricular leukomalacia
Conventional magnetic resonance (MR) imaging shows evidence of brain injury and/or maldevelopment in 70-90% of children with cerebral palsy (CP), though its capability to identify specific white matter tract injury is limited. The great variability of white matter lesions in CP already demonstrated by post-mortem studies is thought to be one of the reasons w
Publicado em: 2009
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4. EVALUATE THE MOTOR AND COGNITIVE DEVELOPMENT OF PREMATURE BABIES WHO HAD BRAIN ULTRASOUND ALTERATIONS AT THE NEONATAL PERIODS / AVALIAÇÃO DO DESENVOLVIMENTO NEUROPSICOMOTOR EM PREMATUROS COM ALTERAÇÕES ULTRA-SONOGRÁFICAS CEREBRAIS NO PERÍODO NEONATAL
The scientific and technologic advances that occurred in the neonatal ITU over the last decades increased the survival rate of babies over and over more premature. Due to the occurency of possible sequelae inherent to this condition, it has been a bigger interest for de development of egress babies from these unites of treatment. The present study is retrosp
Publicado em: 2007
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5. Use of single photon emission computed tomography and magnetic resonance to evaluate central nervous system involvement in patients with juvenile systemic lupus erythematosus
The objective of the present study was to identify the single photon emission computed tomography (SPECT) and magnetic resonance (MR) findings in juvenile systemic lupus erythematosus (JSLE) patients with CNS involvement and to try to correlate them with neurological clinical history data and neurological clinical examination. Nineteen patients with JSLE (16
Brazilian Journal of Medical and Biological Research. Publicado em: 2002-07
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6. A1 adenosine receptors mediate hypoxia-induced ventriculomegaly
Periventricular leukomalacia is characterized by a reduction in brain matter and secondary ventriculomegaly and is a major cause of developmental delay and cerebral palsy in prematurely born infants. Currently, our understanding of the pathogenesis of this condition is limited. In animal models, features of periventricular leukomalacia can be induced by hypo
National Academy of Sciences.
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7. Hypocarbia and cystic periventricular leukomalacia in premature infants
One hundred sixty seven survivors among very low birthweight infants with a gestational age of less than 35 weeks have been studied prospectively. The purpose of this study was to clarify the relationship of severe prenatal and perinatal complications and hypocarbic alkalosis, defined as a carbon dioxide tension (Paco2) of less than or equal to 2.67 kPa and
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8. Cerebral damage in neonates resulting from arteriovenous malformation of the vein of Galen
Seven neonates with arteriovenous malformation of the vein of Galen are described. Six presented with cyanotic heart failure. Two cases had antenatal cerebral infarction, five periventricular leukomalacia, and three recent haemorrhagic infarction. Cerebral damage due to the malformation suggests that surgical correction of the arteriovenous malformation offe
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9. Visual attention as an important visual function: an outline of manifestations, diagnosis and management of impaired visual attention
Impaired visual attention is a common manifestation of cerebral dysfunction. In adults, closed head trauma, cerebral microvascular ischaemia and dementia are common causes. In children, aetiologies include periventricular leukomalacia, hydrocephalus, hypoxic ischaemic encephalopathy and brain damage caused by hypoglycaemia. The resultant visual disability ca
BMJ Group.
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10. Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes
Reactive microglia in the CNS have been implicated in the pathogenesis of white matter disorders, such as periventricular leukomalacia and multiple sclerosis. However, the mechanism by which activated microglia kill oligodendrocytes (OLs) remains elusive. Here we show that lipopolysaccharide (LPS)-induced death of developing OLs is caused by microglia-derive
National Academy of Sciences.
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11. Cerebral autoregulation of preterm neonates--a non-linear control system?
The low frequency cerebral blood flow velocity (CBFV) oscillations in neonates are commonly attributed to an under-dampened immature linear type cerebral autoregulation, and the 'instability' is regarded as causative for peri-intraventricular haemorrhage/periventricular leukomalacia. In contrast, oscillations susceptible to frequency entrainment are a fundam
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12. Calcium-permeable AMPA/kainate receptors mediate toxicity and preconditioning by oxygen-glucose deprivation in oligodendrocyte precursors
Hypoxic–ischemic brain injury in premature infants results in cerebral white matter lesions with prominent oligodendroglial injury and loss, a disorder termed periventricular leukomalacia (PVL). We have previously shown that glutamate receptors mediate hypoxic–ischemic injury to oligodendroglial precursor cells (OPCs) in a model of PVL in the develop
National Academy of Sciences.