Lipid Bilayers
Mostrando 1-12 de 509 artigos, teses e dissertações.
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1. Peptidomic analysis of the venom of the solitary bee Xylocopa appendiculata circumvolans
Abstract Background: Among the hymenopteran insect venoms, those from social wasps and bees - such as honeybee, hornets and paper wasps - have been well documented. Their venoms are composed of a number of peptides and proteins and used for defending their nests and themselves from predators. In contrast, the venoms of solitary wasps and bees have not been
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 28/09/2017
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2. Interaction of antimicrobial peptide Plantaricin149a and four analogs with lipid bilayers and bacterial membranes
The amidated analog of Plantaricin149, an antimicrobial peptide from Lactobacillus plantarum NRIC 149, directly interacts with negatively charged liposomes and bacterial membranes, leading to their lysis. In this study, four Pln149-analogs were synthesized with different hydrophobic groups at their N-terminus with the goal of evaluating the effect of the mod
Braz. J. Microbiol.. Publicado em: 04/02/2014
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3. Antioxidant effect of 4-nerolidylcatechol and α-tocopherol in erythrocyte ghost membranes and phospholipid bilayers
4-Nerolidylcatechol (4-NC) is found in Pothomorphe umbellataroot extracts and is reported to have a topical protective effect against UVB radiation-induced skin damage, toxicity in melanoma cell lines, and antimalarial activity. We report a comparative study of the antioxidant activity of 4-NC and α-tocopherol against lipid peroxidation initiated by two fre
Braz J Med Biol Res. Publicado em: 06/09/2013
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4. Electron paramagnetic resonance (EPR) spectral components of spin-labeled lipids in saturated phospholipid bilayers: effect of cholesterol
Electron paramagnetic resonance (EPR) spectroscopy was used to study the main structural accommodations of spin labels in bilayers of saturated phosphatidylcholines with acyl chain lengths ranging from 16 to 22 carbon atoms. EPR spectra allowed the identification of two distinct spectral components in thermodynamic equilibrium at temperatures below and above
Quím. Nova. Publicado em: 2013
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5. Efeito da carga dos lipídios na interação do BP100 em modelos de membrana / Charge effect of lipids in interaction of BP100 and model membranes
Antimicrobial peptides (AMPs) have been a promising alternative therapy to antibiotics. These molecules, consisting of less than 80 amino acids, with different structures and amino acids composition, have amphipathic character which gives them the ability to act on lipid bilayers. They act, by different mechanisms, over bacteria to mammal cells. The AMPs are
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2012
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6. Molecular interactions of mefenamic acid with lipid bilayers and red blood cells
O ácido mefenâmico é um anti-inflamatório não esteroidal (NSAID), também prescrito no tratamento da dor. No presente trabalho, os efeitos estruturais na membrana de eritrócitos humanos e de modelos moleculares foram investigados. Esta última foi composta em bicamadas construídas de dimiristoilfosfatidilcolina (DMPC) e dimiristoilfosfatidiletanolamin
Journal of the Brazilian Chemical Society. Publicado em: 2011-12
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7. Dispersões lipídicas de dimiristoil fosfatidilglicerol: um estudo termo-estrutural / Lipid dispersions of dymiristoyl phosphatidylglycerol: a thermo-structural study
Dispersions of the saturated anionic phospholipid dimyristoyl phosphatidyl glycerol (DMPG) have been extensively studied regarding their peculiar thermo-structural behavior. At low ionic strength, the gel-fluid transition is spread along nearly 17 ºC, displaying several thermal events in the calorimetric profile, quite different from the single sharp peak a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/12/2010
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8. Estudos experimentais e teóricos dos espectros eletrônicos das sondas fluorescentes Prodan e Laurdan em solventes e bicamadas lipídicas / Experimental and theoretical studies of the electronic spectra of Prodan and Laurdan in solvents and lipid bilayers
As moléculas Prodan (6-propionil-2-dimetilamino-naftaleno) e Laurdan (6- dodecanoil-2-dimetilamina-naftaleno) são muito usadas como sondas fluorescentes em bicamadas lipídicas e, mais raramente, em membranas celulares. Esta tese de doutorado teve por objetivo realizar um estudo dessas sondas em diferentes ambientes, para ampliar o entendimento de suas est
Publicado em: 2010
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9. Caracterização estrutural de agregados formados pelo antifúngico anfotericina B e lipídios catiônicos: uma possível formulação farmacológica / Structural characterization of aggregates formed by the antifungal drug amphotericin B and cationic lipids: a possible pharmacological formulation
Amphotericin B (AB) is a natural antibiotic, produced by Streptomyces nodosus, with a very potent antifungal activity. It is a polyene macrolide molecule, isolated in 1953. Since then, it has been extensively used in the treatment of systemic mycotic infections. Considering AB very low solubility in aqueous medium, it has been largely used as an aqueous disp
Publicado em: 2008
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10. Estudos estruturais de histatina-5 e seu análogo, TOAC0-histatina-5: interação com metais e sistemas biomiméticos / Structural studies of Histatin-5 and its analogue, TOAC0-Histatin-5: interaction with metals and biomimetic systems
The mechanism of action of histatin-5 (Hst-5), an antifungal antimicrobial peptide from human saliva is not completely clarified. Circular dichroism (CD), fluorescence, and electron paramagnetic resonance (EPR) were used to examine the conformational behavior of Hst-5 and its analogue containing the paramagnetic amino acid TOAC at the N-terminus (TOAC0-Hst-5
Publicado em: 2008
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11. Studies of the kinetic characteristics of alkaline phosphatase reconstituted in vesicular systems / Estudos das características cinéticas da fosfatase alcalina reconstituída em sistemas vesiculares
Alkaline phosphatase is a multifunctional enzyme, capable of hydrolyzing phosphate monoesters, pyrophosphate, phosphodiesters, as well as catalyzing transphosphorylation reactions, and it is named "alkaline" due to its ability to perform these reactions more efficiently in pH above the neutral (pH 8-11). The aim of this work was to standardize a methodology
Publicado em: 2008
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12. A mathematical model describing the kinetic of cationic liposome production from dried lipid films adsorbed in a multitubular system
Cationic liposomes are an alternative to DNA non-viral carrier in gene therapy, promoting higher efficiency for transport and delivery into the cells. Liposome production large scale is still a challenge. Among many processes, from dried film adsorbed inside multitubular system promising due its operational simplicity. this field, engineering contributions s
Brazilian Journal of Chemical Engineering. Publicado em: 2007-12