Lipid Hydroperoxides
Mostrando 1-12 de 53 artigos, teses e dissertações.
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1. Age-related changes and effects of regular low-intensity exercise on gait, balance, and oxidative biomarkers in the spinal cord of Wistar rats
The present study aimed to analyze age-related changes to motor coordination, balance, spinal cord oxidative biomarkers in 3-, 6-, 18-, 24-, and 30-month-old rats. The effects of low-intensity exercise on these parameters were also analyzed in 6-, 18-, and 24-month-old rats. Body weight, blood glucose, total cholesterol, and high-density lipoprotein (HDL) ch
Braz J Med Biol Res. Publicado em: 15/07/2019
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2. Treatment with ascorbic acid and α-tocopherol modulates oxidative-stress markers in the spinal cord of rats with neuropathic pain
Vitamin E (vit. E) and vitamin C (vit. C) are antioxidants that inhibit nociception. The effect of these vitamins on oxidative-stress markers in the spinal cord of rats with chronic constriction injury (CCI) of the sciatic nerve is unknown. This study investigated the effect of intraperitoneal administration of vit. E (15 mg·kg-1·day-1) and vit. C (30 mg·
Braz J Med Biol Res. Publicado em: 01/03/2018
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3. Effects of N-acetylcysteine on spinal cord oxidative stress biomarkers in rats with neuropathic pain
N-acetylcysteine (NAC) inhibits nociceptive transmission. This effect has been associated partly with its antioxidant properties. However, the effect of NAC on the levels of lipid hydroperoxides (a pro-oxidant marker), content of ascorbic acid (a key antioxidant molecule of nervous tissue) and total antioxidant capacity (TAC) is unknown. Thus, our study asse
Braz J Med Biol Res. Publicado em: 19/10/2017
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4. Phenolic extract of Parkia biglobosa fruit pulp stalls aflatoxin B1 – mediated oxidative rout in the liver of male rats
The effect of phenolic extract of Parkia biglobosa (Jacq.) R. Br. ex G. Don, Fabaceae, pulp on aflatoxin B1 induced oxidative imbalance in rat liver was evaluated. Thirty-five male rats were randomized into seven groups of five animals each. Rats in group A served as control and received vehicle for drug administration (0.5% DMSO) once daily at 24 h interval
Rev. bras. farmacogn.. Publicado em: 2014-12
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5. Bark Extract of Bathysa cuspidata in the Treatment of Liver Injury Induced by Carbon Tetrachloride in Rats
The aim of this study was to investigate the effect of bark extract Bathysa cuspidata (BCE) in the reconstitution of hepatic parenchyma and stroma after dysfunction induced by the CCl4. Liver lesions were induced by intraperitoneal administration of CCl4 (1 mL/kg) every 48 h for 12 days. The animals were treated with B. cuspidata extract (BCE) administered b
Braz. arch. biol. technol.. Publicado em: 2014-08
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6. Diabetes mellitus triggers oxidative stress in the liver of alloxan-treated rats: a mechanism for diabetic chronic liver disease
PURPOSE: To investigate whether Diabetes mellitus chemically induced by alloxan is capable of changing, in the long term, the oxidative balance in the liver tissue of rats. METHODS: Sixty male Wistar rats, weighing 250-280g, were randomly distributed into two experimental groups: NG - 30 non-diabetic control rats; DG - 30 alloxan- induced diabetic rats witho
Acta Cir. Bras.. Publicado em: 2013-07
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7. Caracterização cinética e busca de inibidores de Ohr (Organic Hydroperoxide Resistance protein) de Xylella fastidiosa. / Kinetic characterization and search for inhibitors of Ohr (Organic Hydroperoxide Resistance protein) from Xylella fastidiosa
A Xylella fastidiosa é uma bactéria gram-negativa, colonizadora do xilema e é o agente responsável por doenças em plantas cultivadas. No Brasil, a principal doença causada por esta bactéria é a CVC (Clorose Variegada dos Citros), a qual traz grandes prejuízos à produção de laranja dos estados de São Paulo e Minas Gerais. Apesar do atual controle
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/04/2012
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8. Effects of Urtica dioica on hepatic ischemia-reperfusion injury in rats
OBJECTIVES: To evaluate the effects of Urtica dioica on hepatic ischemia-reperfusion injury. METHODS: Thirty adult male Wistar albino rats were divided into three groups: sham group (group 1), control group (group 2), and Urtica dioica group (group 3). All the rats were exposed to hepatic ischemia for 60 min, followed by 60 min of reperfusion. In group 2, a
Clinics. Publicado em: 2010
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9. TOXICOLOGIA E FARMACOLOGIA IN VITRO DE NOVOS COMPOSTOS ORGÂNICOS DE SELÊNIO E TELÚRIO COM ATIVIDADE TIPO TIOL PEROXIDASE / TOXICOLOGY AND PHARMACOLOGY OF NEW SELENIUM AND TELLURIUM ORGANIC COMPOUNDS IN VITRO WITH THIOL PEROXIDASE ACTIVITY
Glutathione peroxidase (GPx; EC 1.11.1.9) is a well-known selenoenzyme that catalyzes the reduction of hydrogen peroxide and some organic hydroperoxides by glutathione (GSH) and protects lipid membranes and other cellular components against oxidative stress, which is related to many diseases and this enzyme is regarded as one of the most important antioxidan
Publicado em: 2009
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10. Antibodies against electronegative LDL inhibit atherosclerosis in LDLr-/- mice
In order to determine the effect of antibodies against electronegative low-density lipoprotein LDL(-) on atherogenesis, five groups of LDL low receptor-deficient (LDLr-/-) mice (6 per group) were immunized with the following antibodies (100 µg each): mouse anti-LDL(-) monoclonal IgG2b, rabbit anti-LDL(-) polyclonal IgG or its Fab fragments and mouse irrelev
Brazilian Journal of Medical and Biological Research. Publicado em: 2008-12
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11. Liver oxidative stress of the grey mullet Mugil cephalus presents seasonal variations in Ennore estuary
The objective of this study was to determine the liver oxidative stress status of grey mullets living in heavy-metal-rich polluted Ennore estuary compared with unpolluted Kovalam estuary. Fish were collected from both estuaries during the monsoon and summer seasons from October 2004 to September 2006. Fish liver homogenate (N = 20 per group) was prepared for
Brazilian Journal of Medical and Biological Research. Publicado em: 03/10/2008
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12. Superoxide dismutase and lipid hydroperoxides in blood and endometrial tissue of patients with benign, hyperplastic and malignant endometrium
Resultados epidemiológicos e experimentais apontam para o envolvimento dos radicais derivados do oxigênio na patogênese das moléstias ginecológicas, assim como no desenvolvimento do câncer. O objetivo do presente estudo foi o de examinar as alterações nas atividades e níveis de Cu/Zn superóxido dismutase (CuZnSOD) e hidroperóxidos lipídicos (LOOH
Anais da Academia Brasileira de Ciências. Publicado em: 2008-09