Lower Trypanosomatids
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. Nitro-Heterocyclic compounds induce apoptosis-like effects in Leishmania (L). amazonensis promastigotes
Abstract Background: Three drugs - pentavalent antimonials, amphotericin B and pentamidine - are currently used for leishmaniasis treatment. They are administered for long periods, only parenterally, and have high cardiac, renal and hepatic toxicities. Therefore, the investigation of new compounds is required. Nitro-heterocyclic derivatives have been used a
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 11/03/2019
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2. Slow wilt: another form of Marchitez in oil palm associated with trypanosomatids in Peru
Another form of Marchitez manifestation affecting oil palm (Elaeis guineensis) has been observed since 2002 in the Alto Huallaga area from Peru. Externally, the disease appears as chlorosis, drying and breaking of the lower leaves, rot in fruit bunches, accumulation and rot of spears. Internally, the meristem presents brown lesions with a yellowish halo arou
Trop. plant pathol.. Publicado em: 2013-12
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3. Combination of the essential oil constituents citral, eugenol and thymol enhance their inhibitory effect on Crithidia fasciculata and Trypanosoma cruzi growth
We analyzed the effect of the combination of citral, eugenol and thymol, respectively the main constituents of essential oils of Cympobogon citratus (DC) Stapf, Poaceae (lemon grass), Syzygium aromaticum(L.) Merr. & L.M. Perry, Myrtaceae (clove) and Thymus vulgarisL., Lamiaceae (thyme), on the proliferation of the trypanosomatids Crithidia fasciculataand Try
Rev. bras. farmacogn.. Publicado em: 2013-10
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4. Reatividade de "tripanosomatídeos inferiores": B. culicis, C. deanei, C. fasciculata, C. luciliae, H. samuelpessoai, L. seymouri, P. serpens e W. inconstans com anticorpos de hospedeiros humanos e cães infectados com Leishmania sp. e T. cruzi. / Reactivity of "lower trypanosomatids" : B. culicis, C. deanei, C. fasciculata, C. luciliae, H. samuelpessoai, L. seymouri, P. serpens and W. inconstans with anti-Leishmania sp. and anti-T. cruzi antibodies from human and canine hosts.
"Lower trypanosomatids", that infect plant and insect, present biochemical and molecular similarities to Leishmania sp. and Trypanosoma cruzi. Antigenic similarities between those parasites are known for a long time, but only few comparative investigations about immune humoral cross-reaction were described. In the current work we analyze the cross-immunoreac
Publicado em: 2010
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5. Filogeografia, morfometria e distribuição geográfica potencial de populações de Rhodnius neglectus (Hemiptera, Reduviidae) no Brasil
Sylvatic triatomines of the genus Rhodnius commonly fly into houses in Latin America, maintaining the risk of Chagas disease transmission. In this thesis, phylogeographical, morphological and potential geographical distribution analyses of Rhodnius populations in central Brazil were carried out, focusing in R. neglectus, the major species found in palm trees
Publicado em: 2008
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6. The ubiquitous gp63-like metalloprotease from lower trypanosomatids: in the search for a function
Tripanossomatídeos de insetos e de plantas são informalmente denominados de "tripanossomatídeos inferiores". Estes microrganismos são utilizados rotineiramente como modelos para estudos de bioquímica e de biologia molecular porque são facilmente cultivados sob condições axênicas e porque possuem homólogos aos fatores de virulência encontrados nos
Anais da Academia Brasileira de Ciências. Publicado em: 2006-12
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7. FUNÇÃO DO METAL BIVALENTE NA RNA TRIFOSFATASE DE TRYPANOSOMA CRUZI. / The role of the divalente metal in the RNA triphosphatase from Trypanosoma cruzi.
Cap triphosphatases act in the first step of the mRNA capping process, removing the -phosphoryl group from the 5 end of nascent RNA. Enzymes from trypanosomatids and other lower eukaryotes depend on metals for this catalysis. This contrasts with the cysteine-dependent activity of the corresponding enzymes of mammals. This difference points to these enzymes a
Publicado em: 2006
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8. Susceptibility of an Insect Leptomonas and Crithidia fasciculata to Several Established Antitrypanosomatid Agents
Growth inhibition of the lower trypanosomatids Crithidia fasciculata and a Leptomonas from a hemipteron by several established trypanocides and leishmanicides were compared in four complex and one defined media. The Leptomonas was more susceptible than C. fasciculata in all media, especially to phenanthridines (ethidium, prothidium, isometamidium) and diamid
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9. A single-stranded DNA binding protein binds the origin of replication of the duplex kinetoplast DNA.
Replication of the kinetoplast DNA (kDNA) minicircle of trypanosomatids initiates at a conserved 12-nt sequence, 5'-GGGGTTGGTGTA-3', termed the universal minicircle sequence (UMS). A sequence-specific single-stranded DNA-binding protein from Crithidia fasciculata binds the heavy strand of the 12-mer UMS. Whereas this UMS-binding protein (UMSBP) does not bind