Lung Clearance
Mostrando 1-12 de 333 artigos, teses e dissertações.
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1. Mucociliary Clearance of Different Respiratory Conditions: A Clinical Study
Abstract Introduction Mucociliary clearance (MCC) is the first line of defense of the pulmonary system. Mucociliary clearance impairment may lead to increased risk of respiratory infections, lung injury, pulmonary repair problems, chronic dysfunctions and progression of respiratory diseases. Objective To characterize the MCC of active and passive smokers a
Int. Arch. Otorhinolaryngol.. Publicado em: 2021-01
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2. SARS-CoV-2 viremia may predict rapid deterioration of COVID-19 patients
ABSTRACT COVID-19 has raised worldwide concern as spiraling into a pandemic. Reports about comprehensive investigation of COVID-19 viremia are extremely scanty. Herein, we present four COVID-19 patients with positive SARS-CoV-2 nucleic acid test in blood, accounting for 12.12% of 33 detected cases. Rapid deterioration of these cases with septic shock, accomp
Braz J Infect Dis. Publicado em: 2020-12
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3. Insulin-loaded polymeric mucoadhesive nanoparticles: development, characterization and cytotoxicity evaluation
Abstract Mucoadhesive nanoparticles are particularly interesting for delivery through nasal or pulmonary routes, as an approach to overcome the mucociliary clearance. Moreover, these nanoparticles are attractive for peptide and protein delivery, particularly for insulin to treat diabetes, as an alternative to conventional parenteral administration. Thus, chi
Braz. J. Pharm. Sci.. Publicado em: 07/06/2018
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4. MFG-E8, a clearance glycoprotein of apoptotic cells, as a new marker of disease severity in chronic obstructive pulmonary disease
Milk fat globule epidermal growth factor 8 (MFG-E8) is an opsonin involved in the phagocytosis of apoptotic cells. In patients with chronic obstructive pulmonary disease (COPD), apoptotic cell clearance is defective. However, whether aberrant MFG-E8 expression is involved in this defect is unknown. In this study, we examined the expression of MFG-E8 in COPD
Braz J Med Biol Res. Publicado em: 08/09/2015
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5. Estudo da ação do veneno de Tityus serrulatus sobre a expressão de transportadores de sódio e água em epitélio alveolar de rato / Effect of Tityus serrulatus venom on sodium and water trasporters in rat alveolar epithelium
Acidentes escorpiônicos podem evoluir com edema pulmonar de origem cardiogênica e não cardiogênica. O clearance de edema pulmonar está relacionado principalmente ao transporte ativo de sódio do espaço alveolar para o interstício. O objetivo deste trabalho foi avaliar os efeitos do veneno de Tityus serrulatus e da dexametasona sobre a expressão dos t
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/08/2012
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6. The effects on mucociliary clearance of prednisone associated with bronchial section
OBJECTIVE: Infections have been and remain the major cause of morbidity and mortality after lung transplantation. Because mucociliary clearance plays an important role in human defense mechanisms, the influence of drugs on the mucociliary epithelium of patients undergoing lung transplantation must be examined. Prednisone is the most important corticosteroid
Clinics. Publicado em: 2012
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7. Efeitos da N-acetilcisteína na função pulmonar e renal em ratos com sepse sob ventilação mecânica invasiva / Effects of N-acetylcysteine on pulmonary and renal function on septic rats in invasive mechanical ventilation
Introdução: A sepse pode causar alterações renais e pulmonares. Nos casos mais graves, a ventilação mecânica invasiva (VMI) torna-se necessária para melhorar as trocas gasosas e fornecer adequado oxigênio as células. Entretanto, seu uso está associado com piora da função renal. O estresse oxidativo está aumentado na sepse e relaciona-se com o a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/06/2011
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8. Effects of mycophenolate sodium on mucociliary clearance using a bronchial section and anastomosis rodent model
OBJECTIVE: To study the effects of mycophenolate sodium on mucociliary clearance. INTRODUCTION: Mycophenolate is one of the most commonly used immunosuppressive drugs in lung transplantation. Although its pharmacokinetic properties are well defined, its side effects on mucociliary clearance have not yet been studied. METHODS: Sixty rats were subjected to lef
Clinics. Publicado em: 2011
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9. Efeitos imediatos da circulação extracorpórea sobre o sistema mucociliar / Immediate effects of cardiopulmonary bypass on mucociliary system
BACKGROUND: Cardiopulmonary bypass (CPB) is an important etiologic factor for lung injury observed after cardiac surgery. However, the impact of CPB on respiratory mucociliary function is unknown. The objective of this study was to assess the immediate effects of CPB on mucociliary transport system. METHODS: Twenty-two mixed breed of Large White and Landrace
Publicado em: 2011
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10. Avaliação da função pulmonar em lactentes com displasia broncopulmonar através do teste de multiple breath washout
Introdução: Estudos têm demonstrado obstrução das vias aéreas e redução da capacidade de difusão em lactentes com displasia broncopulmonar (DBP). Entretanto, a fisiopatologia desta doença ainda não está bem definida. O objetivo deste estudo é comparar a capacidade residual functional (CRF) e a heterogeneidade da ventilação pulmonary entre lact
Publicado em: 2011
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11. Lung clearance of 99m TC-DTPA in systemic lupus erythematosus
The early demonstration of lung involvement in systemic lupus erythematosus (SLE) patients is a difficult but important task. In the present study we attempted to identify abnormalities in pulmonary clearance of 99mTc-DTPA in SLE, correlating their clearance data with clinical findings and disease activity. Forty-six consecutive SLE patients with and without
Publicado em: 2010
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12. Efeitos da lesão pulmonar induzida pela ventilação mecânica sobre o epitélio das vias aéreas de condução e sua influência no aparelho mucociliar: modelo experimental em coelhos / Effects of ventilator-induced lung injury on airway-ciliated epithelia and the influence on mucociliary transport system
A ventilação mecânica (VM) pode ser causa de lesão pulmonar sendo este fato reconhecido na literatura como Lesão Pulmonar Induzida pela Ventilação Mecânica (LPIV), onde alterações tanto fisiológicas quanto morfológicas são evidenciadas no pulmão. O objetivo desse trabalho foi avaliar a repercussão das forças envolvidas na ventilação mecâni
Publicado em: 2010