Lung Surfactants
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. Efeitos de alguns tensoativos sobre a viabilidade celular de linhagens celulares de câncer de pulmão
O carcinoma de pulmão (CP) representa um grande desafio à saúde mundial, configurando-se como a principal causa mortis por câncer entre homens e mulheres no Brasil. A história natural da doença inclui elevada letalidade e evolução agressiva, quase sempre com o paciente chegando ao médico quando a doença já se encontra em fase avançada. A incidên
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 15/08/2011
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2. Electron magnetic resonance in studies of biologically-relevant systems. / Ressonância magnética eletrônica no estudo de sistemas de interesse biológico
In this work, we made use of the Electron Paramagnetic Resonance (EPR) spectroscopy along with the so-called reporter group technique and extensive spectral simulations by means of the software NLSL to investigate the interaction of nicotine with model membranes. Besides that we also employed Ferromagnetic Resonance (FMR), which is a technique similar in man
Publicado em: 2009
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3. Efeitos da adição de polietilenoglicol ao surfactante exógeno no tratamento da síndrome de aspiração de mecônio em coelhos recém-nascidos / Effects of polyethylene glycol added to exogenous surfactant for meconium aspiration syndrome treatment in newborn rabbits
Meconium is known to be a potent inactivator of pulmonary surfactant, and exogenous surfactant treatment for meconium aspiration syndrome failed to decrease mortality. A number of studies have shown, in vitro, that the addition of polymers such as polyethylene glycol (PEG) to the surfactant maintains good surface activity in the presence of meconium. In the
Publicado em: 2007
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4. Pulmonary surfactant: hydrophobic nature of the mucosal surface of the human amnion.
The contact angle has been measured for a drop of saline placed upon the rinsed mucosal surface of the amnion in eleven human placental membranes obtained from normal births at full term. The contact angle averaged 70 degrees, indicating a hydrophobic surface comparable with graphite (86 degrees), polyethylene (94 degrees) or oxyntic tissue (85 degrees) whic
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5. Water repellency induced by pulmonary surfactants.
1. Pure cotton fabric was partially carboxylated to produce a tough, porous, hydrophilic sub-phase to stimulate the epithelial membrane of the alveolar wall from a permeability standpoint. 2. Two of the predominant pulmonary surfactants, dipalmitoyl lecithin (DPL) and dipalmitoyl phosphatidylethanolamine (DPPE), were found to inhibit wetting of this syntheti
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6. cDNA and deduced amino acid sequence of human pulmonary surfactant-associated proteolipid SPL(Phe).
Hydrophobic surfactant-associated protein of Mr 6000-14,000 was isolated from ether/ethanol or chloroform/methanol extracts of mammalian pulmonary surfactant. Automated Edman degradation in a gas-phase sequencer showed the major N-terminus of the human low molecular weight protein to be Phe-Pro-Ile-Pro-Leu-Pro-Tyr-Cys-Trp-Leu-Cys-Arg-Ala-Leu-. Because of the
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7. Inhaling to mitigate exhaled bioaerosols
Humans commonly exhale aerosols comprised of small droplets of airway-lining fluid during normal breathing. These “exhaled bioaerosols” may carry airborne pathogens and thereby magnify the spread of certain infectious diseases, such as influenza, tuberculosis, and severe acute respiratory syndrome. We hypothesize that, by altering lung airway surface pro
National Academy of Sciences.
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8. Comparison of surface properties and physiological effects of a synthetic and a natural surfactant in preterm rabbits.
AIMS--To compare the physical and physiological properties of a synthetic surfactant (Exosurf, Wellcome Foundation) and a natural surfactant (Curosurf, Chiesi Farmaceutici). METHODS--Surface properties of the surfactant suspensions (10 mg phospholipid/ml) were evaluated using the pulsating bubble surfactometer. Lung-thorax compliance was determined in 47 imm
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9. Mycoplasma hyopneumoniae p65 Surface Lipoprotein Is a Lipolytic Enzyme with a Preference for Shorter-Chain Fatty Acids
Mycoplasma hyopneumoniae is the most significant bacterial pathogen of the respiratory tract of swine. p65 is an immunodominant surface lipoprotein of M. hyopneumoniae that is specifically recognized during disease. Analysis of the translated amino acid sequence of the gene encoding p65 revealed similarity to the GDSL family of lipolytic enzymes. To examine
American Society for Microbiology.