Mechanisms Of Action
Mostrando 1-12 de 1875 artigos, teses e dissertações.
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1. ATIVIDADE ANTIMICROBIANA DE QUITOSANAS E SEUS DERIVADOS: INFLUÊNCIA DAS CARACTERÍSTICAS ESTRUTURAIS
In recent years, there has been an increasing interest in the development of antimicrobial materials for different applications, especially in the biomedical field. In this context, chitosan is one of the most employed materials due to its highly attractive properties, such as biocompatibility, biodegradability, non-toxicity, and antimicrobial activity again
Química Nova. Publicado em: 2022
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2. Reasons to avoid vitamin D deficiency during COVID-19 pandemic
ABSTRACT The effects of vitamin D on the musculoskeletal system are well established. Its deficiency causes osteomalacia, secondary hyperparathyroidism, and an increased risk for fractures and falls. However, clinical and experimental evidence points to extra-skeletal actions of vitamin D, including on immune and respiratory systems. Thus, during this COVID-
Arch. Endocrinol. Metab.. Publicado em: 2020-10
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3. COMPOSTOS QUIMIOTERÁPICOS DE OURO: UMA VISÃO GERAL DOS COMPLEXOS ANTICÂNCER DE Au(I/III) EM RELAÇÃO À ESTRUTURA DO LIGANTE
Gold compounds engage an important place in the field of medicinal chemistry due to their therapeutic properties. Since the last four decades, Au(I) and Au(III) complexes have attracted the attention of researchers due to their anti-tumor proprieties and the different mechanisms of action they display in comparison to conventional anticancer platinum compoun
Quím. Nova. Publicado em: 2020-09
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4. Influence of the salt concentration on action mechanisms of natamycin against microorganisms of importance in food manufacture
Abstract The objective of this study was to evaluate the influence of salt concentration on action of natamycin on important microorganisms in food manufacturing as this preservative has been used in immersion baths in several dairy products in the country. Strains of Candida albicans, Escherichia coli and Staphylococcus aureus were inoculated at different s
Food Sci. Technol. Publicado em: 2020-06
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5. Metabolization of Insecticidal Amides from Leaves of Piper tuberculatum by Heraclydes hectorides and Naupactus bipes
Amides have been recognized as potent insecticidal natural products but, despite their variety of targets and mechanisms of action, their metabolic fate in insects is virtually unknown. The currently accepted hypothesis is that specialist herbivores are capable of biotransforming xenobiotics rendering them more polar and excretable while generalist insects d
J. Braz. Chem. Soc.. Publicado em: 2020-04
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6. Mesenchymal stem cell therapy in acute kidney injury (AKI): review and perspectives
SUMMARY INTRODUCTION: Acute kidney injury (AKI) is highly prevalent today. It has a multifactorial aetiology and affects people of all ages, genders and ethnicities. Its treatment is essentially supportive of renal function substitution, so new treatment alternatives such as mesenchymal stem cell therapy (MSCs) should be investigated. METHODS: This review
Rev. Assoc. Med. Bras.. Publicado em: 13/01/2020
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7. Bioterrorismo: capacitar para responder
RESUMO A utilização de agentes biológicos com a finalidade de aterrorizar inimigos surgiu há muitos séculos. Essa ação foi popularizada como bioterrorismo. Ataques bioterroristas são perigosos devido ao envolvimento de diversos fatores, como a forma silenciosa na qual pode ocorrer, o tipo e a forma de transmissão do agente biológico utilizado, depe
Saúde debate. Publicado em: 13/01/2020
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8. Effect of fasudil on experimental autoimmune neuritis and its mechanisms of action
This study aimed to investigate the therapeutic effect of fasudil on treating experimental autoimmune neuritis (EAN). Twenty-four EAN mice were randomly assigned to fasudil treatment (Fasudil group) or saline treatment (EAN model group) for 28 days. Clinical symptom score was evaluated every other day; inflammatory cell infiltration, demyelination, anti-myel
Braz J Med Biol Res. Publicado em: 2020-01
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9. A review on medicinal plants used for treating ototoxicity and acoustic trauma induced hearing loss
Hearing loss induced by chemotherapy and acoustic trauma is mainly associated with two factors, free radical formation and apoptosis pathway activation. Despite numerous efforts on reducing the effects of these factors, no definite strategy is still determined to interfere with and control these processes. In recent studies, various protective agents, includ
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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10. Icariin stimulates differentiation of bone marrow-derived mesenchymal stem cells (BM-MSCs) through activation of cAMP/PKA/CREB
Icariin, a prenylated flavonol glycoside isolated from Epimedium, has been considered as a potential alternative therapy for osteoporosis. The present study aimed to clarify the detailed molecular mechanisms of action of icariin on osteoblast function, using bone marrow-derived mesenchymal stem cells (BM-MSCs). BM-MSCs were first stimulated by icariin. Then,
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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11. Machines among the crowd: on the political effects of algorithmic production of social currents
Resumo Neste artigo, discuto algumas maneiras pelas quais os mecanismos de ação coletiva são reconfigurados pela atividade de tecnologias digitais de comunicação. Em especial, examino o modo como os algoritmos mobilizados na Web Social coparticipam da regulação da interdependência entre os elementos que compõem as figurações contemporâneas atrav�
Vibrant, Virtual Braz. Anthr.. Publicado em: 28/11/2019
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12. New tools for cell reprogramming and conversion: Possible applications to livestock
Abstract Somatic cell nuclear transfer and iPS are both forms of radical cell reprogramming able to transform a fully differentiated cell type into a totipotent or pluripotent cell. Both processes, however, are hampered by low efficiency and, in the case of iPS, the application to livestock species is uncertain. Epigenetic manipulation has recently emerged a
Anim. Reprod.. Publicado em: 28/11/2019