Mefenamic Acid
Mostrando 1-12 de 17 artigos, teses e dissertações.
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1. Graphite-Polyurethane Composite Electrode Modified with Molecularly Imprinted Polymer for Determination of Diclofenac
A molecularly imprinted polymer (MIP) was prepared using the anti-inflammatory diclofenac (DCF) as a template. A non-imprinted polymer (NIP) was also prepared as a control. These MIP and NIP were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Brunauer-Emmett-Teller (BET), revealing a higher porosity in the fir
Journal of the Brazilian Chemical Society. Publicado em: 2022
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2. In vitro characterization and in vivo performance of mefenamic acid-sodium diethyldithiocarbamate based liposomes
Mefenamic acid (MFA) is a hydrophobic drug with low dissolution rate. This study aimed to develop stable and reproducible aqueous formulations of MFA using liposomes as drug carriers. The drug entrapment, particles size and drug release profiles, and stability and reproducibility of the liposomes were determined. In addition, the maximum tolerated dose (MTD)
Braz. J. Pharm. Sci.. Publicado em: 25/11/2019
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3. Investigation of the Environmental Transport of Human Pharmaceuticals to Surface Water: A Case Study of Persistence of Pharmaceuticals in Effluent of Sewage Treatment Plants and Hospitals in Malaysia
The present work reports the occurrence and monitoring of 11 pharmaceuticals (i.e., caffeine, prazosin, enalapril, carbamazepine, nifedipine, gliclazide, levonorgestrel, simvastatin, hydrochlorothiazide, diclofenac-Na and mefenamic acid) in surface water and in the influent and effluent of sewage treatment plants (STPs) and hospitals (HSPs). A total of 105 w
J. Braz. Chem. Soc.. Publicado em: 2015-06
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4. Remoção do ácido mefenâmico em água utilizando carvão ativado em pó, lama vermelha e oxidação com cloro
The use of activated carbon powder (ACP), red mud and oxidation with chlorine to remove mefenamic acid in water are described, aimed at their application as a complement to sewage treatment processes in Brazil. A study on the behavior of mefenamic acid in water was performed by evaluating its dissolution for different concentrations and times. Subsequently,
Quím. Nova. Publicado em: 2014
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5. Simultaneous determination of non-steroidal anti-inflammatory drugs in pharmaceutical formulations and human serum by reversed phase high performance liquid chromatography
A rapid and sensitive method using high performance liquid chromatography has been developed and validated for the simultaneous determination of non-steroidal anti-inflammatory drugs (NSAIDs) in pharmaceutical formulations and human serum. Six NSAIDs including: naproxen sodium, diclofenac sodium, meloxicam, flurbiprofen, tiaprofenic and mefenamic acid were a
Química Nova. Publicado em: 2012
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6. Molecular interactions of mefenamic acid with lipid bilayers and red blood cells
O ácido mefenâmico é um anti-inflamatório não esteroidal (NSAID), também prescrito no tratamento da dor. No presente trabalho, os efeitos estruturais na membrana de eritrócitos humanos e de modelos moleculares foram investigados. Esta última foi composta em bicamadas construídas de dimiristoilfosfatidilcolina (DMPC) e dimiristoilfosfatidiletanolamin
Journal of the Brazilian Chemical Society. Publicado em: 2011-12
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7. Characterization of carbon nanotubes-gold nanoparticles composite film modified electrode and voltammetric determination of mefenamic acid
Um novo eletrodo modificado com nanotubos de carbono foi fabricado, com base em nanotubos de carbono multi-paredes (MWCNTs) dispersos em colóide de nanopartículas de ouro (AuNPs). Foi observado que MWCNTs foram dispersos no colóide AuNPs homogeneamente. Fosfato ácido de dihexadecil (DHP) foi adicionado à suspensão para preparar um filme mais estável.
Journal of the Brazilian Chemical Society. Publicado em: 2008
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8. Avaliação do desempenho de diferentes tipos de nanotubos de carbono na determinação de íons metálicos e ácido mefenâmico
This work is summarized in the evaluation of the acting of different types of carbon nanotubes (CNTs) in the determination of metallic íons. The appraised electrodes differ amongst themselves for the form of synthesis of the carbon nanotubes, that they take the formation of different types of NTCs with varied diameters. The multi-walled carbon nanotubes (MW
Publicado em: 2008
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9. Variaveis associadas a determinação do limiar basal de resposta da polpa dental ao estimulo eletrico / Variables associated to pulpal threshold determination with electrical stimulus
There are some unclear aspects about electrical pulpal threshold measure. The objective of this study was to determine the ideal conditions for pulpal threshold measure. Two hundred and fifty six healthy volunteers with teeth able to respond to electrical stimulus were selected and divided in 7 studies. Pulpal threshold was evaluated by means of an electric
Publicado em: 2007
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10. Intercalação de fármacos com atividade antiinflamatória (ácido mefenâmico e piroxicam) em hidróxido duplo lamelar / Intercalation of drugs with antiinflammatory activity (mefenamic acid and piroxicam) in layered double hydroxide
A intercalação de espécies de interesse biológico e terapêutico em Hidróxidos Duplos Lamelares (HDLs) vem se mostrando uma estratégia interessante para a obtenção de sistemas de armazenamento ou carregadores de drogas. No presente trabalho foram investigadas rotas sintéticas e parâmetros experimentais para a intercalação dos ânions derivados do
Publicado em: 2007
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11. Partial molar volume of mefenamic acid in alcohol at temperatures between T=293.15 and T=313.15 K
Volume molar aparente (Vfi), volume molar parcial (V), parâmetro de interação soluto-soluto (Sv), expansividade molar parcial (E(0)2) e coeficiente de expansão térmica isobárica (alfa2) do ácido mefenâmico em seis diferentes solventes orgânicos : metanol, etanol, 1-propanol, 2-propanol, 1-butanol e 2-butanol, foram calculados a partir das densidades
Journal of the Brazilian Chemical Society. Publicado em: 2006-10
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12. Spherical agglomeration of mefenamic acid and nabumetone to improve micromeritics and solubility: A technical note
Spherical agglomeration techniques were developed for improving the flow and compressibility characteristics of microcrystalline mefenamic acid and nabumetone. The process involved agglomerating microcrystals using agglomerating solvents. Temperature and speed of agitation were optimized to obtain spherical agglomerates in a desired range, which was found to
Springer-Verlag.