Mesalazine
Mostrando 1-10 de 10 artigos, teses e dissertações.
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1. Therapeutics in Radiation-induced Proctopathy: A Systematic Review
Abstract Malignant neoplasms are increasingly prevalent in the daily clinical practice. Up to 61% of patients with pelvic malignancies undergo pelvic radiotherapy in different doses, which may cause intestinal damage, and the rectum is the segment most frequently affected due to its fixed position in the pelvis. Currently, there are several strategies to min
Journal of Coloproctology (Rio de Janeiro). Publicado em: 2022
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2. Enemas with mesalazine increase the tissue contents of mucins in the colonic mucosa devoid of fecal stream
Abstract Purpose: To evaluate the inflammatory reaction and measure the content of mucins, in the colonic mucosa without fecal stream submit to intervention with mesalazine. Methods: Twenty-four rats were submitted to a left colostomy and a distal mucous fistula and divided into two groups according to euthanasia to be performed two or four weeks. Each gr
Acta Cir. Bras.. Publicado em: 29/04/2019
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3. Bezoar by mesalazine tablets: cause of intestinal obstruction in Crohn's disease
As formas estenosante e fistulizante da doença de Crohn (DC) apresentam resultado variável ao tratamento medicamentoso e boa resposta à terapia cirúrgica. A prevalência da DC estenosante varia de 12 a 54%, mais frequente nos pacientes com maior tempo de doença, sendo o íleo terminal o local mais acometido. Os farmacobenzoares podem se formar em qualqu
J. Coloproctol. (Rio J.). Publicado em: 2012-12
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4. Development of mesalazine pellets coated with methacrylic-derived polymer
A mesalazina (5-ASA) tem se apresentado como fármaco padrão para o tratamento da doença inflamatória intestinal (DII) devido ao seu efeito local na mucosa intestinal e colônica. A terapia efetiva e segura desta doença requer a chegada da substância ativa ao seu local de ação com maior eficiência. Nessa busca, tem se destacado o uso de Sistemas Mult
Brazilian Journal of Pharmaceutical Sciences. Publicado em: 2011-03
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5. TNF-alfa, IL1-beta and IL-8 expressions in ileal mucosa of Crohn s disease patients using mesalazine or azathioprine / Estudo comparativo das expressões de TNF-alfa, IL1-beta e IL-8 na mucosa ileal de portadores da Doença de Crohn em uso de mesalazina ou azatioprina
Crohn s disease is an inflammatory bowel disease that is not currently understood. Much research is being carried out in order to comprehend its mechanisms of lesion and the inflammatory mediators involved in this disease. New advances in molecular biology have opened up new possibilities for further understanding this intricate pathology, yet, some doubts r
Publicado em: 2009
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6. Micropartículas poliméricas à base de xilana e Eudragit S-100 contendo mesalazina visando à liberação cólon-específica
Colon-specific drug delivery systems have attracted increasing attention from the pharmaceutical industry due to their ability of treating intestinal bowel diseases (IBD), which represent a public health problem in several countries. In spite of being considered a quite effective molecule for the treatment of IBD, mesalazine (5-ASA) is rapidly absorbed in th
Publicado em: 2009
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7. Síntese, caracterização e avaliação do perfil de liberação "in vitro" de hidrogéis do álcool polivinílico ph sensitivos processados por métodos físico-químico
In this study hydrogels of poly(vinyl alcohol) (PVA) processed by chemical method and gamma radiation were obtained in order to evaluate the pH responsive behaviour of those systems as well the utilization for the targeted drug delivery in the gastrointestinal tract of Human. The rheological properties of PVA solutions with different hydrolysis degree and we
Publicado em: 2007
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8. Mesalazine as a maintenance treatment in Crohn's disease: is it the long awaited solution?
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9. Distinct Elevation of Levels of Anti-Caenorhabditis elegans Antibody in Sera of Patients with Inflammatory Bowel Disease
Dysregulation of immune responses to intestinal exogenous antigens contributes to the pathogenesis of inflammatory bowel disease, but the specific antigen responsible for the pathogenesis of inflammatory bowel disease is unknown. We measured serum antibody titers against Caenorhabditis elegans antigens. Immunoglobulin G (IgG) and IgG subclass anti-C. elegans
American Society for Microbiology.
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10. Preventive Effects of Escherichia coli Strain Nissle 1917 on Acute and Chronic Intestinal Inflammation in Two Different Murine Models of Colitis
Escherichia coli strain Nissle 1917 (EcN) is as effective in maintaining remission in ulcerative colitis as is treatment with mesalazine. This study aims to evaluate murine models of acute and chronic intestinal inflammation to study the antiinflammatory effect of EcN in vivo. Acute colitis was induced in mice with 2% dextran-sodium sulfate (DSS) in drinking
American Society for Microbiology.